TRPM2

transient receptor potential cation channel, subfamily M, member 2

Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD+), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has ADP-ribose pyrophosphatase activity.

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Proteins (2)

Type

Over-Expression Lysate (2)

Target

TRPM2 (2)

Publications

No (2)

Tag

Myc-DDK (Flag) (2)

Species

Human (1)

Source

293T Cells (1)

HEK 293 Cells (1)

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TRPM2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117424

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

171.7 kDa

Price:

100 µg/$710

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Human TRPM2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83310

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

171.7 kDa

Price:

20 µg/$215

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