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TRPC7

transient receptor potential cation channel, subfamily C, member 7

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) By similarity. May also be activated by intracellular calcium store depletion.

Gene Name: transient receptor potential cation channel, subfamily C, member 7
Family/Subfamily: Ion Channel , Calcium channel - TRP
Synonyms: TRPC7, KNP3, Trrp8, Transient receptor protein 7, TRP-7, TRP7, HTRP7
Target Sequences: NM_020389 NP_065122.1 Q9HCX4

Publications (1)

1
A key role of TRPC channels in the regulation of electromechanical activity of the developing heart. Sabourin J, Robin E, Raddatz E. Cardiovascular research. 2011 92:226-36. [PubMed:21672930] Related Antibodies: LS-C108107.

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).