TRPA1

transient receptor potential cation channel, subfamily A, member 1

Receptor-activated non-selective cation channel involved in detection of pain and possibly also in cold perception and inner ear function. Has a central role in the pain response to endogenous inflammatory mediators and to a diverse array of volatile irritants, such as mustard oil, garlic and acrolein, an irritant from tears gas and vehicule exhaust fumes. Acts also as a ionotropic cannabinoid receptor by being activated by delta(9)-tetrahydrocannabinol (THC), the psychoactive component of marijuana. Not involved in menthol sensation. May be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds. Probably operated by a phosphatidylinositol second messenger system.

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Proteins (3)

Type

Recombinant (3)

Target

TRPA1 (3)

Product Group

Alzheimer's Disease (3)

Publications

No (3)

Tag

6His-SUMO, N-terminus (1)

GST, N-terminus (1)

His-T7 (1)

Species

Human (3)

Source

E. coli (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human TRPA1 Protein (Recombinant His-T7) (aa63-370) - LS-G25652

Source:

E. coli

Tag:

His-T7

Molecular Weight:

37.6 kDa

Price:

10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164

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Human TRPA1 Protein (Recombinant GST, N-terminus) (aa1033-1117) - LS-G60945

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human TRPA1 Protein (Recombinant 6His-SUMO, N-terminus) (aa957-1119) - LS-G56603

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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