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TRIP / LRRFIP1

leucine rich repeat (in FLII) interacting protein 1

Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.

Gene Name:	leucine rich repeat (in FLII) interacting protein 1
Synonyms:	LRRFIP1, FLAP-1, FLAP1, FLIIAP1, GCF2, LRR FLII-interacting protein 1, HUFI-1, Tcf9, Tcf-9, TRIP, NEDD8-conjugating enzyme, TAR RNA-interacting protein, Transcription factor 9, GC-binding factor 2, GCF-2
Target Sequences:	NM_004735 NP_004726.2 Q32MZ4

Human TRIP / LRRFIP1 (Sandwich ELISA) ELISA Kit - LS-F8790

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$834

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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