TRIM72 / MG53

tripartite motif containing 72

Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca2+-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles.

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Products

ELISA Kits (4)

Type

Sandwich (4)

Target

TRIM72 / MG53 (4)

Reactivity

Human (1)

Mouse (2)

Rat (1)

Format

96-Well Strip Plate (4)

Publications

No (4)

Sample Type

Cell Lysates (2)

Plasma (4)

Serum (4)

Tissue Homogenates (3)

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Human TRIM72 / MG53 (Sandwich ELISA) ELISA Kit - LS-F52768

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

25 - 1600 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$958

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Mouse TRIM72 / MG53 (Sandwich ELISA) ELISA Kit - LS-F13482

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Rat TRIM72 / MG53 (Sandwich ELISA) ELISA Kit - LS-F54047

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

18.75 - 1200 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$958

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Mouse TRIM72 / MG53 (Sandwich ELISA) ELISA Kit - LS-F34262

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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