TRIB2

tribbles pseudokinase 2

TRIB2 is one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

TRIB2 (6)

Publications

No (6)

Tag

GST (1)

GST, N-terminus (1)

His, N-terminus + GST, C-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

HEK 293 Cells (2)

Insect Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (1)

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Human TRIB2 Protein (Recombinant His, N-terminus + GST, C-terminus) (Met1-Asn343) - LS-G137941

Source:

Insect Cells

Tag:

His, N-terminus + GST, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

66 kDa

Price:

50 µg/$561

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Human TRIB2 Protein (Recombinant GST, N-terminus) (aa254-343) - LS-G62287

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human TRIB2 Protein (Recombinant GST) (Full Length) - LS-G33355

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

63.47 kDa

Price:

10 µg/$479; 25 µg/$670

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Human TRIB2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76312

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.6 kDa

Price:

20 µg/$150

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Human TRIB2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65798

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.6 kDa

Price:

20 µg/$1,107

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TRIB2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101756

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.6 kDa

Price:

100 µg/$494

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