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TRIAP1
TP53 Regulated Inhibitor Of Apoptosis 1
Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis.
| Gene Name: | TP53 Regulated Inhibitor Of Apoptosis 1 |
| Synonyms: | TRIAP1, 15E1.1, HSPC132, MDM35, WF-1, p53CSV, Protein 15E1.1 |
| Target Sequences: | NM_016399 NP_057483.1 |
Publications (1)
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