TRF1 / TERF1

telomeric repeat binding factor (NIMA-interacting) 1

Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.

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Products

ELISA Kits (4)

Type

Cell-Based Phosphorylation (1)

DNA Binding Phosphorylation (1)

Sandwich (2)

Target

TRF1 / TERF1 (4)

Reactivity

Human (4)

Mouse (2)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (2)

96-Well Strip Plate (1)

Publications

No (4)

Sample Type

Adherent Cell Cultures (1)

Cell Lysates (2)

Nuclear Lysates (1)

Plasma (1)

Serum (1)

Tissue Homogenates (1)

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Human TRF1 / TERF1 (Sandwich ELISA) ELISA Kit - LS-F8761

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$834

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Human TRF1 / TERF1 (Sandwich ELISA) ELISA Kit - LS-F21204

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Mouse/Human Phospho-TRF1 / TERF1 (DNA-Binding Phosphorylation ELISA) ELISA Kit - LS-F935

Type:

DNA Binding Phosphorylation

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Nuclear Lysates

Price:

1 Plate/$694

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Mouse/Human Phospho-TRF1 / TERF1 (Ser219) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1440

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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