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TREM2 / TREM-2

triggering receptor expressed on myeloid cells 2

TREM2 / TREM-2 is a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Name: triggering receptor expressed on myeloid cells 2
Synonyms: TREM2, Trem2b, TREM-2, Trem2a, Trem2c
Target Sequences: NM_018965 NP_061838.1 Q9NZC2

Publications (3)

1
Dark microglia: A new phenotype predominantly associated with pathological states. Bisht K, Sharma KP, Lecours C, Sánchez MG, El Hajj H, Milior G, Olmos-Alonso A, Gómez-Nicola D, Luheshi G, Vallières L, Branchi I, Maggi L, Limatola C, Butovsky O, Tremblay MÈ. Glia. 2016 64:826-39. (IHC; Mouse) [Full Text Article] [PubMed:26847266] [PMC:PMC4949554]
2
TREM2 governs Kupffer cell activation and explains belr1 genetic resistance to malaria liver stage infection. Gonçalves LA, Rodrigues-Duarte L, Rodo J, Vieira de Moraes L, Marques I, Penha-Gonçalves C. Proceedings of the National Academy of Sciences of the United States of America. 2013 110:19531-6. (WB; Mouse) [Full Text Article] [PubMed:24218563] Related Antibodies: LS-C272143.
3
microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration. Bhattacharjee S, Zhao Y, Dua P, Rogaev EI, Lukiw WJ. PloS one. 2016 March;11:e0150211. [Full Text Article] [PubMed:26949937] [PMC:PMC4780721]

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ELISA Kits (10)
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TREM2 / TREM-2 (10)
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Cell Culture Supernatants (3)
Cell Lysates (3)
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Serum (10)
Tissue Homogenates (6)
TREM2 / TREM-2 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
TREM2 / TREM-2 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$818
TREM2 / TREM-2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$834
TREM2 / TREM-2 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$854
TREM2 / TREM-2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
TREM2 / TREM-2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
TREM2 / TREM-2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$958
TREM2 / TREM-2 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, EDTA Plasma, Heparin Plasma, Serum
1 Plate/$795
TREM2 / TREM-2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
TREM2 / TREM-2 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
28 - 7000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$672
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).