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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Treacle / TCOF1

Treacher Collins-Franceschetti syndrome 1

TCOF1 protein is required during embryonic development for proper nucleolar-cytoplasmic trafficking in branchial arches-derived tissues. Loss of function mutations in the TCOF1 or Treacle gene lead to the Treacher Collins Syndrome, an autosomal dominant disease characterized by malformations of the mandibulofacial region. Affected patients suffer from cranofacial deformity such as cleft palate and hearing loss. The mouse gene is widely expressed.

Gene Name: Treacher Collins-Franceschetti syndrome 1
Synonyms: TCOF1, Treacle, MFD1, TCS1, Treacle protein
Target Sequences: NM_000356 NP_000347.2 Q13428

Filtered by: None
Target
Treacle / TCOF1 (10)
Reactivity
Human (10)
Mouse (5)
Application
IHC (8)
IHC-P (3)
WB (9)
ELISA (5)
ICC (1)
IF (5)
Peptide-ELISA (1)
Host
rabbit (9)
mouse (1)
Isotype
IgG (6)
IgG1,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (9)
Clone
8H3 (1)
Format
Unconjugated (10)
Epitope
10-90 aa, N-terminal (1)
Gln55 (1)
N-Terminus (1)
aa1189-1488 (1)
aa41-90 (1)
Publications
No (10)
Showing 1-10 of 10 results

IHC-plus™ Treacle / TCOF1 Antibody (N-Terminus) LS-B15639
Rabbit Polyclonal to Human Treacle / TCOF1
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50µl 1mg/ml  $425.00
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 5 ug/ml.
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 5 ug/ml.

Treacle / TCOF1 Antibody (clone 8H3) LS-C198318
Mouse Monoclonal [clone 8H3] (IgG1,k) to Human Treacle / TCOF1
Human
ELISA, IF, WB
Unconjugated
100µg  $365.00
Immunofluorescence of monoclonal antibody to TCOF1 on HeLa cell . [antibody concentration 10 ug/ml]
Western Blot analysis of TCOF1 expression in transfected 293T cell line by TCOF1 monoclonal antibody (M02), clone 8H3.Lane 1: TCOF1 transfected lysate(152.104 KDa).Lane 2: Non-transfected lysate.

IHC-plus™ Treacle / TCOF1 Antibody (aa41-90) LS-B8409
Rabbit Polyclonal (IgG) to Human Treacle / TCOF1
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-Treacle / TCOF1 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
Western blot analysis of lysates from Jurkat, 293, HeLa cells, using TCOF1 Antibody. The lane on the right is blocked with the synthesized peptide.

Treacle / TCOF1 Antibody LS-C804539
Rabbit Polyclonal (IgG) to Human Treacle / TCOF1
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Immunofluorescence Image

Treacle / TCOF1 Antibody LS-C660944
Rabbit Polyclonal (IgG) to Human Treacle / TCOF1
Human
ELISA, IF, IHC, WB
Unconjugated
100µg  $465.00

Treacle / TCOF1 Antibody (10-90 aa, N-terminal) LS-C386495
Rabbit Polyclonal (IgG) to Human Treacle / TCOF1
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00

Treacle / TCOF1 Antibody (aa1189-1488) LS-C377467
Rabbit Polyclonal (IgG) to Human Treacle / TCOF1
Human
ELISA, IHC, IHC-P
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human tonsil using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human thymus using antibody at 1:100 dilution.

Treacle / TCOF1 Antibody (Gln55) LS-C191973
Rabbit Polyclonal to Human Treacle / TCOF1
Mouse, Human
IHC, WB
Unconjugated
100µl  $345.00

Treacle / TCOF1 Antibody LS-C341328
Rabbit Polyclonal to Human Treacle / TCOF1
Human
IHC, WB
Unconjugated
100µl 1mg/ml  $385.00

Treacle / TCOF1 Antibody LS-C749077
Rabbit Polyclonal (IgG) to Human Treacle / TCOF1
Mouse, Human
WB
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00
Showing 1-10 of 10 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).