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TRDMT1 / DNMT2

tRNA aspartic acid methyltransferase 1

TRDMT1 / DNMT2 is a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa.

Gene Name:	tRNA aspartic acid methyltransferase 1
Family/Subfamily:	C5-methyltransferase
Synonyms:	TRDMT1, DMNT2, DNA MTase homolog HsaIIP, DNMT2, M.HsaIIP, MHSAIIP, RNMT1, DNA methyltransferase-2, PUMET
Target Sequences:	NM_004412 NP_004403.1 O14717

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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