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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TRB3 / TRIB3

tribbles pseudokinase 3

Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity. Inhibits the transcriptional activity of DDIT3/CHOP and is involved in DDIT3/CHOP-dependent cell death during ER stress. Can inhibit APOBEC3A editing of nuclear DNA.

Gene Name: tribbles pseudokinase 3
Synonyms: TRIB3, C20orf97, NIPK, SINK, TRB-3, TRB3, DJ1103G7.3, SKIP3, Tribbles homolog 3
Target Sequences: NM_021158 NP_066981.2 Q96RU7

Filtered by: None
Target
TRB3 / TRIB3 (84)
Reactivity
Human (76)
Mouse (22)
Rat (4)
Bovine (4)
Chimpanzee (3)
Gibbon (3)
Guinea pig (4)
Orangutan (3)
Pig (4)
Rabbit (4)
Application
IHC (42)
IHC-P (21)
WB (61)
ELISA (34)
IF (1)
IP (1)
Peptide-ELISA (1)
Host
rabbit (72)
mouse (12)
Isotype
IgG (37)
IgG1 (12)
Clonality
monoclonal mc (12)
polyclonal pc (72)
Clone
OTI1F6 (2)
OTI2D11 (2)
OTI3C6 (2)
OTI3F3 (2)
OTI3F6 (2)
OTI3G4 (2)
Format
AP Conjugated (5)
APC Conjugated (5)
Azide-free (5)
Biotin Conjugated (9)
Carrier-free (6)
FITC Conjugated (9)
HRP Conjugated (9)
PE Conjugated (5)
Unconjugated (42)
Epitope
N-Terminus (18)
aa1-200 (12)
aa15-45 (8)
aa301-331 (8)
aa305-334 (8)
C-Terminus (7)
aa71-120 (4)
aa315-332 (2)
aa112-125 (1)
aa305-354 (1)
aa314-349 (1)
Publications
No (84)
Showing 1-25 of 84 results

IHC-plus™ TRB3 / TRIB3 Antibody (C-Terminus) LS-A3372
Rabbit Polyclonal to Human TRB3 / TRIB3
Human
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-TRIB3 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRB3 / TRIB3 Antibody (C-Terminus, Biotin) LS-A103891
Rabbit Polyclonal to Human TRB3 / TRIB3
Human
IHC, IHC-P
Biotin Conjugated
100µl  $650.00
Anti-TRIB3 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRB3 / TRIB3 Antibody (C-Terminus, FITC) LS-A103892
Rabbit Polyclonal to Human TRB3 / TRIB3
Human
IHC, IHC-P
FITC Conjugated
100µl  $650.00
Anti-TRIB3 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRB3 / TRIB3 Antibody (C-Terminus, APC) LS-A103890
Rabbit Polyclonal to Human TRB3 / TRIB3
Human
IHC, IHC-P
APC Conjugated
100µl  $650.00
Anti-TRIB3 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRB3 / TRIB3 Antibody (C-Terminus, Azide-free, HRP) LS-A103893
Rabbit Polyclonal to Human TRB3 / TRIB3
Human
IHC, IHC-P
HRP Conjugated, Azide-free
100µl  $650.00
Anti-TRIB3 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRB3 / TRIB3 Antibody (C-Terminus, PE) LS-A103894
Rabbit Polyclonal to Human TRB3 / TRIB3
Human
IHC, IHC-P
PE Conjugated
100µl  $650.00
Anti-TRIB3 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRB3 / TRIB3 Antibody LS-B12111
Rabbit Polyclonal (IgG) to Human TRB3 / TRIB3
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05mg 1mg/ml  $425.00
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

TRB3 / TRIB3 Antibody (N-Terminus) LS-C153584
Rabbit Polyclonal to Human TRB3 / TRIB3
Human
ELISA, IHC, WB
Unconjugated
100µg 100µl 1mg/ml  $345.00

TRB3 / TRIB3 Antibody (aa305-334) LS-C164592
Rabbit Polyclonal to Mouse TRB3 / TRIB3
Mouse
WB
Unconjugated
400µl  $325.00

IHC-plus™ TRB3 / TRIB3 Antibody (N-Terminus) LS-A2976
Rabbit Polyclonal to Human TRB3 / TRIB3
Human
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-TRIB3 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRB3 / TRIB3 Antibody (N-Terminus, Biotin) LS-A103477
Rabbit Polyclonal to Human TRB3 / TRIB3
Human
IHC, IHC-P
Biotin Conjugated
100µl  $650.00
Anti-TRIB3 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRB3 / TRIB3 Antibody (N-Terminus, APC) LS-A103476
Rabbit Polyclonal to Human TRB3 / TRIB3
Human
IHC, IHC-P
APC Conjugated
100µl  $650.00
Anti-TRIB3 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ TRB3 / TRIB3 Antibody (N-Terminus, AP) LS-A103475
Rabbit Polyclonal to Human TRB3 / TRIB3
Human
IHC, IHC-P
AP Conjugated
100µl  $650.00
Anti-TRIB3 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

TRB3 / TRIB3 Antibody (aa1-200, clone OTI3G4) LS-C340343
Mouse Monoclonal [clone OTI3G4] (IgG1) to Human TRB3 / TRIB3
Human
IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $345.00
IHC of paraffin-embedded Human Kidney tissue using anti-TRIB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TRIB3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TRIB3.

TRB3 / TRIB3 Antibody (aa1-200, clone OTI3C6) LS-C340290
Mouse Monoclonal [clone OTI3C6] (IgG1) to Human TRB3 / TRIB3
Human
IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $345.00
IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-TRIB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
IHC of paraffin-embedded Human Kidney tissue using anti-TRIB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

TRB3 / TRIB3 Antibody (aa1-200, clone OTI3C6, Carrier-free) LS-C791264
Mouse Monoclonal [clone OTI3C6] (IgG1) to Human TRB3 / TRIB3
Human
IHC, WB
Unconjugated, Carrier-free
100µg  $395.00
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-TRIB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-TRIB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,

TRB3 / TRIB3 Antibody (aa112-125) LS-C345005
Rabbit Polyclonal to Human TRB3 / TRIB3
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100µg  $325.00
Immunohistochemical staining of human tissue using anti-TRB3 (human), pAb at 1:2000 dilution. . 1: Immunoperoxidase staining (cytoplasmic) of formalin-fixed, paraffin-embedded human salivary glands (200x, brown color).
Western blot analysis of human tissue lysate using anti-TRB3 (human), pAb at 1:2,000 dilution. 1. Human spleen tissue lysate (10 ug). 2. Human liver tissue lysate (10 ug). 3. Human colon tissue lysate (10 ug). 4. Human Thpok (His-tagged) (negative control).

TRB3 / TRIB3 Antibody (aa1-200, clone OTI3F3) LS-C340346
Mouse Monoclonal [clone OTI3F3] (IgG1) to Human TRB3 / TRIB3
Human
IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $345.00
IHC of paraffin-embedded Human pancreas tissue using anti-TRIB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-TRIB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

TRB3 / TRIB3 Antibody (aa1-200, clone OTI3F3, Carrier-free) LS-C791324
Mouse Monoclonal [clone OTI3F3] (IgG1) to Human TRB3 / TRIB3
Human
IHC, WB
Unconjugated, Carrier-free
100µg  $395.00
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-TRIB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-TRIB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,

TRB3 / TRIB3 Antibody (aa1-200, clone OTI3F6) LS-C794059
Mouse Monoclonal [clone OTI3F6] (IgG1) to Human TRB3 / TRIB3
Human
IHC, WB
Unconjugated
100µl 1mg/ml  $345.00
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-TRIB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-TRIB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,

TRB3 / TRIB3 Antibody (aa1-200, clone OTI3F6, Carrier-free) LS-C791266
Mouse Monoclonal [clone OTI3F6] (IgG1) to Human TRB3 / TRIB3
Human
IHC, WB
Unconjugated, Carrier-free
100µg  $395.00
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-TRIB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
Western blot analysis of extracts. (35ug) from 9 different cell lines by using anti-TRIB3 monoclonal antibody. (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine;rat; MCF7: human). (1:200)

TRB3 / TRIB3 Antibody (aa1-200, clone OTI1F6) LS-C340288
Mouse Monoclonal [clone OTI1F6] (IgG1) to Human TRB3 / TRIB3
Human
IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $345.00
IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-TRIB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
IHC of paraffin-embedded Human lymph node tissue using anti-TRIB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

TRB3 / TRIB3 Antibody (aa1-200, clone OTI1F6, Carrier-free) LS-C791267
Mouse Monoclonal [clone OTI1F6] (IgG1) to Human TRB3 / TRIB3
Human
IHC, WB
Unconjugated, Carrier-free
100µg  $395.00
Immunohistochemical staining of paraffin-embedded Human lymph node tissue within the normal limits using anti-TRIB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-TRIB3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,

TRB3 / TRIB3 Antibody (aa15-45) LS-C100924
Rabbit Polyclonal to Human TRB3 / TRIB3
Human
IHC, IHC-P, WB
Unconjugated
400µl  $325.00
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Western blot of NPK(arrow) using rabbit polyclonal NPK Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the TRIB3 gene (Lane 2) (Origene Technologies).

TRB3 / TRIB3 Antibody (aa15-45) LS-C330712
Rabbit Polyclonal (IgG) to Human TRB3 / TRIB3
Human
ELISA, IHC, WB
Unconjugated
200µl  $590.00
Showing 1-25 of 84 results

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).