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TRAP1 / HSP75

TNF receptor-associated protein 1

Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.

Gene Name: TNF receptor-associated protein 1
Synonyms: TRAP1, HSP 75, HSP75, HSP90L, TNFR-associated protein 1, TRAP-1
Target Sequences: NM_016292 NP_057376.2 Q12931

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Products
Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
TRAP1 / HSP75 (4)
No (4)
GST (1)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
TRAP1 / HSP75 Protein - 12.5% SDS-PAGE of human TRAP1 stained with Coomassie Blue
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Wheat Germ Extract
GST
106.4 kDa
2 µg/$439
TRAP1 / HSP75 Protein - Recombinant Heat Shock Protein 75kDa, Mitochondrial By SDS-PAGE
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E. coli
His-T7
83.8 kDa
10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198
TRAP1 / HSP75 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
79.9 kDa
20 µg/$150
TRAP1 / HSP75 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
79.9 kDa
100 µg/$494
Viewing 1-4 of 4 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).