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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TRAIL-R4 / DCR2

tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL, and DcR1/TRID is a decoy receptor. Another member of the TRAIL receptor family was more recently identified and designated DcR2, TRAIL-R4, or TRUNDD. DcR2 has an extracellular TRAIL-binding domain but lacks intracellular death domain and does not induce apoptosis. Like DR4 and DR5, DcR2 transcript is widely expressed in normal human tissues. Overexpression of DcR2 attenuated TRAIL-induced apoptosis.

Gene Name: tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
Family/Subfamily: TNF Receptor , not assigned-TNF Receptor
Synonyms: TNFRSF10D, CD264, Decoy receptors 2, DCR2, TRAILR4, TRAIL-R4, TRUNDD, CD264 antigen, Decoy receptor 2, TRAIL receptor 4
Target Sequences: NM_003840 NP_003831.2 Q9UBN6

Filtered By: None
Target
TRAIL-R4 / DCR2 (59)
Reactivity
Human (57)
Mouse (2)
Rat (2)
Cynomolgus (1)
Rhesus monkey (1)
Application
IHC (19)
IHC-Fr (1)
IHC-P (10)
WB (42)
Flo (14)
ELISA (34)
ICC (2)
IF (1)
IP (2)
Peptide-ELISA (1)
Host
rabbit (51)
mouse (8)
Isotype
IgG (39)
IgG1 (8)
Clonality
monoclonal mc (8)
polyclonal pc (51)
Clone
6G7G1 (1)
7G7H9 (1)
HS402 (1)
TRAIL-R4-01 (4)
Format
AP Conjugated (3)
APC Conjugated (4)
Biotin Conjugated (4)
FITC Conjugated (5)
HRP Conjugated (4)
PE Conjugated (4)
Unconjugated (35)
Epitope
aa252-278 (8)
aa254-283 (8)
aa257-386 (2)
90-170 aa, Internal (1)
Extracellular Domain (1)
Internal (1)
N-Terminus (1)
aa1-210 (1)
aa105-154 (1)
aa249-263 (1)
Publications
No (59)
Showing 1-25 of 59 results

TRAIL-R4 / DCR2 Antibody (aa105-154) IHC-plus™ LS-B14709
Rabbit Polyclonal (IgG) to Human TRAIL-R4 / DCR2
Human
IHC IHC-P Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $425.00
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot analysis of the lysates from K562 cells using TNFRSF10D antibody.
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot analysis of the lysates from K562 cells using TNFRSF10D antibody.

TRAIL-R4 / DCR2 Antibody (aa249-263) LS-C287
Rabbit Polyclonal (IgG) to Human TRAIL-R4 / DCR2
Mouse, Rat, Human
ICC IF IHC WB
Unconjugated
100µg 1mg/ml  $365.00
Immunohistochemistry of DcR2 in mouse kidney node tissue with DcR2 antibody at 2.5 µg/ml.
Immunocytochemical staining of HeLa cells using DcR2 antibody at 10 ug/ml.
Immunohistochemistry of DcR2 in mouse kidney node tissue with DcR2 antibody at 2.5 µg/ml.
Immunocytochemical staining of HeLa cells using DcR2 antibody at 10 ug/ml.

TRAIL-R4 / DCR2 Antibody (clone TRAIL-R4-01, FITC) LS-C112508
Mouse Monoclonal [clone TRAIL-R4-01] (IgG1) to Human TRAIL-R4 / DCR2
Human
Flo
FITC Conjugated
100µg 1mg/ml  $350.00

TRAIL-R4 / DCR2 Antibody (clone TRAIL-R4-01, PE) LS-C112538
Mouse Monoclonal [clone TRAIL-R4-01] (IgG1) to Human TRAIL-R4 / DCR2
Human
Flo
PE Conjugated
100µg 1mg/ml  $395.00

TRAIL-R4 / DCR2 Antibody (aa1-210, clone TRAIL-R4-01) LS-C355221
Mouse Monoclonal [clone TRAIL-R4-01] (IgG1) to Human TRAIL-R4 / DCR2
Human
Flo
Unconjugated
100µg 1mg/ml  $385.00

TRAIL-R4 / DCR2 Antibody (clone HS402) LS-C344769
Mouse Monoclonal [clone HS402] (IgG1) to Human TRAIL-R4 / DCR2
Human
Flo ICC IHC IHC-Fr IP
Unconjugated
100µg  $415.00

TRAIL-R4 / DCR2 Antibody (aa257-386) LS-C380052
Rabbit Polyclonal (IgG) to Human TRAIL-R4 / DCR2
Human
ELISA IHC IHC-P WB
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human tonsil using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human tonsil using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.

TRAIL-R4 / DCR2 Antibody LS-C489586
Rabbit Polyclonal to Human TRAIL-R4 / DCR2
Human
ELISA IHC IHC-P IP WB
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00

TRAIL-R4 / DCR2 Antibody LS-C318902
Rabbit Polyclonal (IgG) to Human TRAIL-R4 / DCR2
Human
ELISA IHC IHC-P WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human kidney using TNFRSF10D / TRAIL-R4 / DCR2 antibody at dilution of 1:100.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunohistochemistry of paraffin-embedded human kidney using TNFRSF10D / TRAIL-R4 / DCR2 antibody at dilution of 1:100.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TRAIL-R4 / DCR2 Antibody (HRP) LS-C317469
Rabbit Polyclonal (IgG) to Human TRAIL-R4 / DCR2
Human
ELISA IHC IHC-P WB
HRP Conjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human kidney using TNFRSF10D / TRAIL-R4 / DCR2 antibody at dilution of 1:100.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunohistochemistry of paraffin-embedded human kidney using TNFRSF10D / TRAIL-R4 / DCR2 antibody at dilution of 1:100.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TRAIL-R4 / DCR2 Antibody (Biotin) LS-C317467
Rabbit Polyclonal (IgG) to Human TRAIL-R4 / DCR2
Human
ELISA IHC IHC-P WB
Biotin Conjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human kidney using TNFRSF10D / TRAIL-R4 / DCR2 antibody at dilution of 1:100.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunohistochemistry of paraffin-embedded human kidney using TNFRSF10D / TRAIL-R4 / DCR2 antibody at dilution of 1:100.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TRAIL-R4 / DCR2 Antibody (FITC) LS-C317468
Rabbit Polyclonal (IgG) to Human TRAIL-R4 / DCR2
Human
ELISA IHC IHC-P WB
FITC Conjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human kidney using TNFRSF10D / TRAIL-R4 / DCR2 antibody at dilution of 1:100.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunohistochemistry of paraffin-embedded human kidney using TNFRSF10D / TRAIL-R4 / DCR2 antibody at dilution of 1:100.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TRAIL-R4 / DCR2 Antibody LS-C665010
Rabbit Polyclonal (IgG) to Human TRAIL-R4 / DCR2
Human
ELISA IHC WB
Unconjugated
100µg  $375.00

TRAIL-R4 / DCR2 Antibody (aa252-278) LS-C325831
Rabbit Polyclonal (IgG) to Human TRAIL-R4 / DCR2
Human
ELISA Flo WB
Unconjugated
200µl  $530.00

TRAIL-R4 / DCR2 Antibody (aa252-278, Biotin) LS-C520495
Rabbit Polyclonal (IgG) to Human TRAIL-R4 / DCR2
Human
ELISA Flo WB
Biotin Conjugated
200µl  $680.00

TRAIL-R4 / DCR2 Antibody (aa252-278, APC) LS-C271864
Rabbit Polyclonal (IgG) to Human TRAIL-R4 / DCR2
Human
ELISA Flo WB
APC Conjugated
200µl  $680.00

TRAIL-R4 / DCR2 Antibody (aa252-278, PE) LS-C271865
Rabbit Polyclonal (IgG) to Human TRAIL-R4 / DCR2
Human
ELISA Flo WB
PE Conjugated
200µl 0.45mg/ml  $635.00

TRAIL-R4 / DCR2 Antibody (aa252-278, AP) LS-C271863
Rabbit Polyclonal (IgG) to Human TRAIL-R4 / DCR2
Human
ELISA Flo WB
AP Conjugated
200µl  $680.00

TRAIL-R4 / DCR2 Antibody LS-C403032
Rabbit Polyclonal (IgG) to Human TRAIL-R4 / DCR2
Human
ELISA IHC WB
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human thyroid cancer using CCR6 Polyclonal Antibody at dilution of 1:50.
Western blot analysis of A431, HepG2, Raji and K562 cell, using CCR6 Polyclonal Antibody at dilution of 1:966.
Immunohistochemistry of Human thyroid cancer using CCR6 Polyclonal Antibody at dilution of 1:50.
Western blot analysis of A431, HepG2, Raji and K562 cell, using CCR6 Polyclonal Antibody at dilution of 1:966.

TRAIL-R4 / DCR2 Antibody (aa257-386) LS-C380058
Rabbit Polyclonal (IgG) to Human TRAIL-R4 / DCR2
Human
ELISA IHC IHC-P
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human tonsil using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human tonsil using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.

TRAIL-R4 / DCR2 Antibody LS-C489587
Rabbit Polyclonal to Cynomolgus TRAIL-R4 / DCR2
Cynomolgus
ELISA IHC IHC-P
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00

TRAIL-R4 / DCR2 Antibody LS-C342267
Rabbit Polyclonal to Human TRAIL-R4 / DCR2
Human
IHC WB
Unconjugated
100µl 1mg/ml  $385.00

TRAIL-R4 / DCR2 Antibody LS-C334520
Rabbit Polyclonal (IgG) to Human TRAIL-R4 / DCR2
Human
IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded human stomach cancer using TNFRSF10D antibody at dilution of 1:200 (400x lens).
Immunohistochemistry of paraffin-embedded human stomach cancer using TNFRSF10D antibody at dilution of 1:200 (400x lens).

TRAIL-R4 / DCR2 Antibody LS-C401586
Rabbit Polyclonal (IgG) to Human TRAIL-R4 / DCR2
Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human thyroid cancer using TNFRSF10D Polyclonal Antibody at dilution of 1:60.
Immunohistochemistry of Human thyroid cancer using TNFRSF10D Polyclonal Antibody at dilution of 1:60.
Immunohistochemistry of Human thyroid cancer using TNFRSF10D Polyclonal Antibody at dilution of 1:60.
Immunohistochemistry of Human thyroid cancer using TNFRSF10D Polyclonal Antibody at dilution of 1:60.

TRAIL-R4 / DCR2 Antibody LS-C406271
Rabbit Polyclonal (IgG) to Human TRAIL-R4 / DCR2
Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human thyroid cancer using CCR6 Polyclonal Antibody at dilution of 1:50.
Immunohistochemistry of Human thyroid cancer using CCR6 Polyclonal Antibody at dilution of 1:50.
Immunohistochemistry of Human thyroid cancer using CCR6 Polyclonal Antibody at dilution of 1:50.
Immunohistochemistry of Human thyroid cancer using CCR6 Polyclonal Antibody at dilution of 1:50.
Showing 1-25 of 59 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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