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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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We could not find product '(ID:15554)'. Here are some alternate products to this target that might be of interest to you.



TRAIL-R3 / DCR1

tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL. Two decoy receptors for TRAIL have been identified and designated DcR1/TRID/TRAIL-R3/LIT and DcR2/TRAIL-R4/TRUNDD. DcR1 has extracellular TRAIL-binding domain but lacks intracellular signaling domain. It is a glycophospholipid-anchored cell surface protein. DcR1 transcripts were expressed in many normal human tissues but not in most cancer cell lines. Overexpression of DcR1 did not induce apoptosis, but attenuated TRAIL-induced apoptosis.

Gene Name: tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
Family/Subfamily: TNF Receptor , not assigned-TNF Receptor
Synonyms: TNFRSF10C, CD263 antigen, CD263, Cytotoxic TRAIL receptor-3, Decoy receptor 1, DCR1, DCR1-TNFR, LIT, Lymphocyte inhibitor of TRAIL, TRAIL-R3, TRAILR3, TRAIL receptor 3, TRID
Target Sequences: NM_003841 NP_003832.2 O14798

Publications (1)

1
Expression of the multidrug transporter P-glycoprotein is inversely related to that of apoptosis-associated endogenous TRAIL. Souza PS, Madigan JP, Gillet JP, Kapoor K, Ambudkar SV, Maia RC, Gottesman MM, Fung KL. Experimental cell research. 2015 August;336:318-28. (Human) [Full Text Article] [PubMed:26101157] [PMC:PMC4522412]

Viewing 1-25 of 59 items
TRAIL-R3 / DCR1 Antibody - Immunohistochemistry detection of endogenous TRAIL-R3 in paraffin-embedded human carcinoma tissues (colon, tonsil) using mAb to TRAIL-R3 (TR3.06) .
Select
Mouse Monoclonal [clone TR3.06] (IgG1) to Human TRAIL-R3 / DCR1
Human
Flo, IHC, IHC-P, WB
Unconjugated
100µg   1mg/ml   $415.00
Select
Mouse Monoclonal [clone TRAIL-R3-02] (IgG1) to Human TRAIL-R3 / DCR1
Human
Flo
Unconjugated
100µg   1mg/ml   $385.00
TRAIL-R3 / DCR1 Antibody - Flow cytometric analysis of Human TNFRSF10C(CD263) expression on human whole blood granulocytes. Cells were stained with purified anti-Human TNFRSF10C(CD263), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes.
Select
Rabbit Monoclonal [clone 003] (IgG) to Human TRAIL-R3 / DCR1
Human
Flo
Unconjugated, Preservative Free
50µl   $245.00; 100µl   $305.00
TRAIL-R3 / DCR1 Antibody - Surface staining of human DcR1 transfected cells with anti-human DcR1 (DJR3) PE. Appropriate isotype controls were used (open histogram). Total viable cells were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone DJR3] (IgG1,k) to Human TRAIL-R3 / DCR1
Human
Flo
PE Conjugated
100tst   $375.00
TRAIL-R3 / DCR1 Antibody - Western blot of TRAIL-R3 / DCR1 antibody.
Select
Rabbit Polyclonal to Human TRAIL-R3 / DCR1
Human
WB
Unconjugated
20µl   0.5mg/ml   $195.00; 100µl   0.5mg/ml   $245.00; 200µl   0.5mg/ml   $285.00; 1ml   0.5mg/ml   $475.00
Select
Goat Polyclonal to Human TRAIL-R3 / DCR1
Human
ELISA, Flo, ICC, IHC, WB
Unconjugated
200µg   $475.00
TRAIL-R3 / DCR1 Antibody - Immunocytochemistry of DcR1 in HeLa cells with DcR1 antibody at 10 µg/ml.
Select
Rabbit Polyclonal (IgG) to Human TRAIL-R3 / DCR1
Mouse, Rat, Human
ELISA, ICC, IF, WB
Unconjugated
0.1mg   $365.00
TRAIL-R3 / DCR1 Antibody - Flow cytometric analysis of Human TNFRSF10C(CD263) expression on human whole blood granulocytes. Cells were stained with APC-conjugated anti-Human TNFRSF10C(CD263). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes.
Select
Rabbit Monoclonal [clone 003] (IgG) to Human TRAIL-R3 / DCR1
Human
Flo
APC Conjugated
25tst   0.1mg/ml   $225.00; 100tst   0.1mg/ml   $345.00
TRAIL-R3 / DCR1 Antibody - Flow cytometric analysis of Human TNFRSF10C(CD263) expression on human whole blood granulocytes. Cells were stained with FITC-conjugated anti-Human TNFRSF10C(CD263). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes.
Select
Rabbit Monoclonal [clone 003] (IgG) to Human TRAIL-R3 / DCR1
Human
Flo
FITC Conjugated
25tst   0.1mg/ml   $225.00; 100tst   0.1mg/ml   $345.00
TRAIL-R3 / DCR1 Antibody - Flow cytometric analysis of Human TNFRSF10C(CD263) expression on human whole blood granulocytes. Cells were stained with PE-conjugated anti-Human TNFRSF10C(CD263). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes.
Select
Rabbit Monoclonal [clone 003] (IgG) to Human TRAIL-R3 / DCR1
Human
Flo
PE Conjugated
25tst   0.1mg/ml   $225.00; 100tst   0.1mg/ml   $345.00
Select
Rat Monoclonal (IgG2a) to Mouse TRAIL-R3 / DCR1
Mouse
ELISA, IHC, IHC-Fr, WB
Unconjugated
100µg   $650.00
Select
Mouse Monoclonal (IgG1) to Human TRAIL-R3 / DCR1
Human
Flo, ICC, WB
Unconjugated
100µg   $665.00
TRAIL-R3 / DCR1 Antibody
Select
Rabbit Polyclonal (IgG) to Human TRAIL-R3 / DCR1
Rat, Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
TRAIL-R3 / DCR1 Antibody - ICC/IF analysis of TNFRSF10C in HeLa cells. The cell was stained with TNFRSF10C antibody (1:100).The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).
Select
Mouse Monoclonal [clone AT1E12] (IgG1,k) to Human TRAIL-R3 / DCR1
Human
ELISA, ICC, WB
Unconjugated
50µl   1mg/ml   $275.00; 100µl   1mg/ml   $345.00
TRAIL-R3 / DCR1 Antibody - Immunofluorescence of DcR1 in Rat Liver cells with DcR1 antibody at 20 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human TRAIL-R3 / DCR1
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
0.1mg   $365.00
Select
Mouse Monoclonal [clone HS301] (IgG1) to Human TRAIL-R3 / DCR1
Human
Flo, ICC
Unconjugated
100µg   $415.00
TRAIL-R3 / DCR1 Antibody - Immunofluorescent analysis of A549 cells using TNFRSF10C Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Select
Rabbit Polyclonal (IgG) to Human TRAIL-R3 / DCR1
Human
ELISA, IF
Unconjugated
50µg   $285.00; 100µg   $385.00
Select
Rat Monoclonal (IgG2a) to Human TRAIL-R3 / DCR1
Human
Flo, WB
Unconjugated
100µg   $620.00
Select
Rat Monoclonal (IgG2a) to Human TRAIL-R3 / DCR1
Human
Flo, WB
Unconjugated
100µg   $385.00
TRAIL-R3 / DCR1 Antibody - Western blot of TNFRSF10C pAb in extracts from human spleen tissue.
Select
Rabbit Polyclonal to Human TRAIL-R3 / DCR1
Human
IHC, WB
Unconjugated
100µl   $385.00
Select
Rabbit Polyclonal (IgG) to Human TRAIL-R3 / DCR1
Rat, Human
Flo, WB
Unconjugated
100µg   $425.00
TRAIL-R3 / DCR1 Antibody - Western blot analysis of human spleen cell lysate.
Select
Rabbit Polyclonal (IgG) to Human TRAIL-R3 / DCR1
Mouse, Rat, Human
IHC, WB
Unconjugated
50µl   $235.00; 100µl   $315.00; 200µl   $425.00
Select
Rabbit Polyclonal (IgG) to Human TRAIL-R3 / DCR1
Human
ELISA, WB
Unconjugated
100µg   100µl   1mg/ml   $275.00
Select
Rabbit Polyclonal to Human TRAIL-R3 / DCR1
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µl   $530.00
Select
Rabbit Polyclonal (IgG) to Human TRAIL-R3 / DCR1
Human
ELISA, WB
Unconjugated
50µg   $345.00; 100µg   $435.00

Viewing 1-25 of 59 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).