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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TRAF6

TNF receptor-associated factor 6, E3 ubiquitin protein ligase

TRAF6 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain. Two alternatively spliced transcript variants, encoding an identical protein, have been reported.

Gene Name: TNF receptor-associated factor 6, E3 ubiquitin protein ligase
Synonyms: TRAF6, RING finger protein 85, MGC:3310, RNF85
Target Sequences: NM_004620 NP_004611.1 Q9Y4K3

Filtered by: None
Target
TRAF6 (60)
Reactivity
Human (50)
Mouse (36)
Rat (24)
Bat (9)
Bovine (7)
Chimpanzee (6)
Dog (5)
Gibbon (6)
Hamster (1)
Horse (5)
Monkey (4)
Pig (6)
Rabbit (9)
Application
IHC (15)
IHC-Fr (1)
IHC-P (7)
WB (60)
ELISA (18)
ICC (4)
IF (6)
IP (7)
Peptide-ELISA (1)
RNAi (1)
Host
rabbit (58)
mouse (1)
hamster (1)
Isotype
IgG (26)
IgG2b,k (1)
Clonality
monoclonal mc (2)
polyclonal pc (58)
Clone
1B2 (1)
1F8 (1)
Format
AP Conjugated (2)
APC (2)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (6)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (4)
Unconjugated (29)
Epitope
C-Terminus (10)
aa153-423 (8)
aa254-475 (8)
aa314-343 (8)
Internal (2)
His154 (1)
aa105-154 (1)
aa436-449 (1)
aa451-469 (1)
aa471-520 (1)
aa472-522 (1)
Publications
No (60)
Showing 1-25 of 60 results

IHC-plus™ TRAF6 Antibody (C-Terminus) LS-B190
Rabbit Polyclonal (IgG) to Human TRAF6
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
50µg 0.25mg/ml  $485.00
Anti-TRAF6 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ TRAF6 Antibody LS-B4867
Rabbit Polyclonal to Human TRAF6
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100µl 0.3mg/ml  $485.00
Anti-TRAF6 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Immunofluorescence of methanol-fixed HeLa, using TRAF6 antibody at 1:200 dilution.

IHC-plus™ TRAF6 Antibody LS-B207
Rabbit Polyclonal (IgG) to Human TRAF6
Mouse, Rat, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
50µg 1mg/ml  $545.00
Anti-TRAF6 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Immunofluorescence of TRAF6 in K562 cells with TRAF6 antibody at 20 ug/ml.

TRAF6 Antibody (aa451-469) LS-C148303
Rabbit Polyclonal to Human TRAF6
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human
IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
50µl  $335.00
Formalin-fixed, paraffin- embedded tissue sections stained for TRAF6 using Polyclonal Antibody to TRAF6 at 1:2000. Hematoxylin-Eosin counterstain. A, mouse lymph node. B, mouse bone marrow.
Formalin-fixed, paraffin- embedded tissue sections stained for TRAF6 using Polyclonal Antibody to TRAF6 at 1:2000. Hematoxylin-Eos in counterstain. A, mouse spleen. B, mouse thymus.

TRAF6 Antibody LS-C331172
Rabbit Polyclonal (IgG) to Human TRAF6
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunofluorescence analysis of HeLa cells using TRAF6 antibody. Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using TRAF6 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking.

TRAF6 Antibody (clone 1B2) LS-C198368
Mouse Monoclonal [clone 1B2] (IgG2b,k) to Human TRAF6
Human
ELISA, RNAi, WB
Unconjugated
50µg  $365.00
Western Blot analysis of TRAF6 expression in transfected 293T cell line by TRAF6 monoclonal antibody (M02), clone 1B2.Lane 1: TRAF6 transfected lysate(59.6 KDa).Lane 2: Non-transfected lysate.
Detection limit for recombinant GST tagged TRAF6 is approximately 1 ng/ml as a capture antibody.

IHC-plus™ TRAF6 Antibody LS-B11779
Rabbit Polyclonal (IgG) to Mouse TRAF6
Mouse
IHC, IHC-P, IP, WB
Unconjugated
50µg 1mg/ml  $425.00
Mouse Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Mouse Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)

TRAF6 Antibody LS-C801460
Rabbit Polyclonal (IgG) to Human TRAF6
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Western blot Image

TRAF6 Antibody (aa153-423) LS-C296689
Rabbit Polyclonal to Human TRAF6
Human
ICC, IP, WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $530.00
Western blot of recombinant TRAF6.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot; Sample:Human A431 Cells.

TRAF6 Antibody (aa153-423, PE) LS-C727775
Rabbit Polyclonal to Human TRAF6
Human
WB
PE Conjugated
100µl 0.1mg/ml  $245.00; 200µl 0.1mg/ml  $285.00; 1ml 0.1mg/ml  $475.00
Western blot of recombinant TRAF6.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot; Sample:Human A431 Cells.

TRAF6 Antibody LS-C661213
Rabbit Polyclonal (IgG) to Human TRAF6
Human
ELISA, IF, IHC, WB
Unconjugated
100µg  $435.00

TRAF6 Antibody (Internal) LS-C386496
Rabbit Polyclonal (IgG) to Human TRAF6
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00
Western blot of TRAF6 antibody

TRAF6 Antibody LS-C358730
Rabbit Polyclonal to Human TRAF6
Mouse, Bovine, Rat, Human
IHC, IP, WB
Unconjugated
50µl  $325.00

TRAF6 Antibody (Internal) LS-C413175
Rabbit Polyclonal to Human TRAF6
Mouse, Bovine, Rat, Pig, Human
IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $275.00
Immunohistochemical analysis of TRAF6 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Western blot analysis of TRAF6 expression in HeLa (A); K562 (B); Rat kidney (C); Rat heart (D); mouse kidney (E) whole cell lysates.

TRAF6 Antibody (His154) LS-C177724
Rabbit Polyclonal to Human TRAF6
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100µl  $345.00
IHC of TRAF6 (H154) pAb in paraffin-embedded human testis tissue.
Western blot of TRAF6 (H154) pAb in extracts from HeLa cells.

TRAF6 Antibody (aa105-154) LS-C291750
Rabbit Polyclonal (IgG) to Human TRAF6
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunohistochemistry analysis of TRAF6 antibody in paraffin-embedded human testis tissue.
Western blot analysis of lysate from HeLa cells, using TRAF6 antibody.

TRAF6 Antibody LS-C771358
Rabbit Polyclonal (IgG) to Human TRAF6
Mouse, Rat, Human
IF, WB
Unconjugated
60µl 1mg/ml  $235.00; 120µl 1mg/ml  $295.00; 200µl 1mg/ml  $395.00

TRAF6 Antibody LS-C417195
Rabbit Polyclonal to Human TRAF6
Mouse, Rat, Human
IHC, WB
Unconjugated
100µg  $305.00

TRAF6 Antibody LS-C192297
Rabbit Polyclonal to Human TRAF6
Mouse, Rat, Human
IHC, WB
Unconjugated
100µl  $385.00
Western blot of TRAF6 pAb in extracts from K562, 293T, COS7 cells and mouse brain, liver tissues.

TRAF6 Antibody (C-Terminus) LS-C10911
Rabbit Polyclonal (IgG) to Human TRAF6
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µg  $495.00

TRAF6 Antibody (HRP) LS-C550156
Rabbit Polyclonal (IgG) to Human TRAF6
Mouse, Rat, Human
ELISA, WB
HRP Conjugated
100µl  $680.00

TRAF6 Antibody (FITC) LS-C539990
Rabbit Polyclonal (IgG) to Human TRAF6
Mouse, Rat, Human
ELISA, WB
FITC Conjugated
100µl  $680.00

TRAF6 Antibody (AP) LS-C511965
Rabbit Polyclonal (IgG) to Human TRAF6
Mouse, Rat, Human
ELISA, WB
AP Conjugated
100µl  $680.00

TRAF6 Antibody (aa314-343) LS-C325915
Rabbit Polyclonal (IgG) to Human TRAF6
Human
ELISA, WB
Unconjugated
200µl  $590.00

TRAF6 Antibody (clone 1F8) LS-C179819
Hamster Monoclonal [clone 1F8] (IgG) to Mouse TRAF6
Mouse
IP, WB
Unconjugated
100µg 1mg/ml  $350.00
Immunoprecipitation Image
Showing 1-25 of 60 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).