TRAF3IP2 / ACT1

TRAF3 interacting protein 2

Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kB associates with IkB proteins in the cell cytoplasm, which inhibit NF-kB activity. IkB is phosphorylated by IkB kinase (IKK) complex that contains IKKa, IKKb, and IKKg. A novel molecule that associates with and activates IKK was recently identified and designated CIKS (for connection to IKK and SAPK/JNK) and Act1 (for NF-kB activator 1). CIKS directly interacts with IKKg. CIKS/Act1 also activates activating transcription factor (ATF) and activator protein 1 (AP-1) through Jun kinase (JNK). These results indicate that CIKS/Act1 is involved in the inflammation and stress responses. CIKS/Act1 is ubiquitously expressed in human tissues.

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

TRAF3IP2 / ACT1 (4)

Publications

No (4)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human TRAF3IP2 / ACT1 Protein (Recombinant GST, N-terminus) (aa451-565) - LS-G61634

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human TRAF3IP2 / ACT1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87386

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

63.4 kDa

Price:

20 µg/$150

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Human TRAF3IP2 / ACT1 Protein (Recombinant GST) (Full Length) - LS-G32325

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

90 kDa

Price:

2 µg/$439

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TRAF3IP2 / ACT1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G106518

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

63.4 kDa

Price:

100 µg/$494

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