TPSG1 / Tryptase Gamma 1

tryptase gamma 1

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. There is uncertainty regarding the number of genes in this cluster. Currently four functional genes - alpha I, beta I, beta II and gamma I - have been identified. And beta I has an allelic variant named alpha II, beta II has an allelic variant beta III, also gamma I has an allelic variant gamma II. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha-tryptases predominant. This gene differs from other members of the tryptase gene family in that it has C-terminal hydrophobic domain, which may serve as a membrane anchor. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.

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Products

ELISA Kits (3)

Type

Custom (1)

Sandwich (2)

Target

TPSG1 / Tryptase Gamma 1 (3)

Reactivity

Human (2)

Mouse (1)

Format

96-Well Strip Plate (3)

Publications

No (3)

Sample Type

Plasma (2)

Serum (2)

Tissue Homogenates (1)

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Mouse TPSG1 / Tryptase Gamma 1 (Custom ELISA) ELISA Kit - LS-F15787

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Human TPSG1 / Tryptase Gamma 1 (Sandwich ELISA) ELISA Kit - LS-F12866

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human TPSG1 / Tryptase Gamma 1 (Sandwich ELISA) ELISA Kit - LS-F35972

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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