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TPP1 / CLN2

tripeptidyl peptidase I

TPP1 / CLN2 is a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.

Gene Name: tripeptidyl peptidase I
Family/Subfamily: Protease , Serine S53
Synonyms: TPP1, CLN2, GIG1, LPIC, LINCL, TPP-I, Tripeptidyl aminopeptidase, Tripeptidyl peptidase I, Tripeptidyl-peptidase 1, Tripeptidyl-peptidase I, TPP-1, Growth-inhibiting protein 1
Target Sequences: NM_000391 NP_000382.3 O14773

☰ Filters
Products
Proteins (9)
Over-Expression Lysate (2)
Recombinant (7)
TPP1 / CLN2 (9)
No (9)
6His, C-terminus (1)
GST (1)
GST, N-terminus (1)
His (1)
His,C-terminus (1)
His-S (1)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (7)
Mouse (1)
293T Cells (1)
Baculovirus (1)
E. coli (2)
HEK 293 Cells (1)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (2)
Purified (1)
Low endotoxin level (3)
TPP1 / CLN2 Protein - Recombinant Tripeptidyl Peptidase I By SDS-PAGE
Select
E. coli
His-S
38.2 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
TPP1 / CLN2 Protein - Recombinant  Tripeptidyl Peptidase I By SDS-PAGE
Select
E. coli
His-T7
43.2 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
TPP1 / CLN2 Protein - 12.5% SDS-PAGE of human TPP1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
87.6 kDa
2 µg/$439
TPP1 / CLN2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
TPP1 / CLN2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
61.25 kDa
20 µg/$150
TPP1 / CLN2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
61.25 kDa
100 µg/$494
Select
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
60.35 kDa
10 µg/$344; 50 µg/$584
Select
Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
60.7 kDa
50 µg/$854
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
60.35kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
Viewing 1-9 of 9 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).