TPMT

thiopurine S-methyltransferase

TPMT is the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.

☰ Filters

Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

TPMT (6)

Publications

No (6)

Tag

GST (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (1)

Select

Human TPMT Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67104

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28 kDa

Price:

20 µg/$1,107

Select

Human TPMT Protein (Recombinant His-T7) (aa26-227) - LS-G25118

Source:

E. coli

Tag:

His-T7

Molecular Weight:

26.9 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

Select

Human TPMT Protein (Recombinant GST) (Full Length) - LS-G30762

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

52.69 kDa

Price:

10 µg/$479; 25 µg/$670

Select

Human TPMT Protein (Recombinant) - LS-G3580

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

100 µg/$411; 500 µg/$985; 20 µg/$276

Select

Human TPMT Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79136

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28 kDa

Price:

20 µg/$150

Select

TPMT Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99016

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28 kDa

Price:

100 µg/$494

Viewing 1-6 of 6 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.