LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us

TPM3

Tropomyosin 3

TPM3 is a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants.

Gene Name: Tropomyosin 3
Synonyms: TPM3, CFTD, Cytoskeletal tropomyosin TM30, Gamma-tropomyosin, NEM1, Hscp30, TM30nm, Tropomyosin alpha-3 chain, TM-5, TM5, TPMsk3, Tropomyosin 3, Tropomyosin-5, TM3, TM30, TRK, Tropomyosin-3, HTM5, OK/SW-cl.5, Tropomyosin gamma
Target Sequences: NM_152263 NP_689476.2 P06753

Filtered By: None
Target
TPM3 (37)
Reactivity
Human (27)
Mouse (19)
Rat (6)
Bat (4)
Bovine (4)
Chicken (4)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (4)
Horse (4)
Monkey (4)
Orangutan (3)
Pig (4)
Rabbit (4)
Sheep (4)
Xenopus (4)
Zebrafish (4)
Application
IHC (24)
IHC-P (3)
WB (33)
ELISA (8)
ICC (5)
IF (3)
Peptide-ELISA (1)
Host
rabbit (35)
mouse (2)
Isotype
IgG (32)
IgG1,k (1)
IgG2a,k (1)
Clonality
monoclonal mc (2)
polyclonal pc (35)
Clone
1649CT306.29.13 (1)
2E4 (1)
Format
APC (2)
APC Conjugated (2)
Biotin Conjugated (6)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (6)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (13)
Epitope
aa1-285 (10)
aa6-248 (10)
aa143-192 (4)
aa245-276 (1)
Publications
No (37)
Showing 1-25 of 37 results

TPM3 Antibody (clone 2E4) IHC-plus™ LS-B8022
Mouse Monoclonal [clone 2E4] (IgG2a,k) to Human TPM3
Human
ELISA IHC IHC-P WB
Unconjugated
50µg 0.5mg/ml  $485.00
Anti-TPM3 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 20 ug/ml.
Detection limit for recombinant GST tagged TPM3 is 0.1 ng/ml as a capture antibody.
Anti-TPM3 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 20 ug/ml.
Detection limit for recombinant GST tagged TPM3 is 0.1 ng/ml as a capture antibody.

TPM3 Antibody IHC-plus™ LS-B11912
Rabbit Polyclonal (IgG) to Human TPM3
Mouse, Human
IF IHC IHC-P WB
Unconjugated
50µl  $425.00
Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunofluorescence analysis of HeLa cells using TPM3 antibody. Blue: DAPI for nuclear staining.
Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunofluorescence analysis of HeLa cells using TPM3 antibody. Blue: DAPI for nuclear staining.

TPM3 Antibody LS-C482272
Rabbit Polyclonal to Human TPM3
Mouse, Rat, Human
ICC IF IHC IHC-P WB
Unconjugated
50µl 1mg/ml  $255.00; 100µl 1mg/ml  $295.00; 200µl 1mg/ml  $375.00
Immunohistochemical analysis of Tropomyosin 3 staining in mouse heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of Tropomyosin 3 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
Immunohistochemical analysis of Tropomyosin 3 staining in mouse heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of Tropomyosin 3 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.

TPM3 Antibody (aa143-192) LS-C101891
Rabbit Polyclonal (IgG) to Human TPM3
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey
WB
Unconjugated
50µg  $365.00
TPM3 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
TPM3 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

TPM3 Antibody LS-C499976
Rabbit Polyclonal (IgG) to Human TPM3
Human
ELISA IF IHC
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human liver cancer using TPM3 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using TPM3 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human liver cancer using TPM3 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using TPM3 Antibody at dilution of 1:100

TPM3 Antibody LS-C661188
Rabbit Polyclonal (IgG) to Human TPM3
Human
ELISA IHC WB
Unconjugated
100µg  $435.00

TPM3 Antibody LS-C661189
Rabbit Polyclonal (IgG) to Human TPM3
Human
ELISA IHC WB
Unconjugated
100µg  $465.00

TPM3 Antibody (aa6-248) LS-C374749
Rabbit Polyclonal (IgG) to Mouse TPM3
Mouse
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $265.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $545.00; 10ml 0.5mg/ml  $2,160.00
Western blot of TPM3 antibody.
Western blot of TPM3 antibody.

TPM3 Antibody (aa6-248, HRP) LS-C712504
Rabbit Polyclonal (IgG) to Mouse TPM3
Mouse
IHC WB
HRP Conjugated
20µl  $215.00; 100µl  $295.00; 200µl  $345.00; 1ml  $695.00; 10ml  $2,805.00
Western blot of TPM3 antibody.
Western blot of TPM3 antibody.

TPM3 Antibody (aa6-248, Biotin) LS-C423171
Rabbit Polyclonal (IgG) to Mouse TPM3
Mouse
ICC WB
Biotin Conjugated
100µl 0.5mg/ml  $375.00

TPM3 Antibody (aa6-248, Biotin) LS-C687886
Rabbit Polyclonal (IgG) to Mouse TPM3
Mouse
IHC WB
Biotin Conjugated
20µl  $205.00; 100µl  $275.00; 200µl  $315.00; 1ml  $590.00; 10ml  $2,370.00
Western blot of TPM3 antibody.
Western blot of TPM3 antibody.

TPM3 Antibody (aa6-248, FITC) LS-C423173
Rabbit Polyclonal (IgG) to Mouse TPM3
Mouse
ICC WB
FITC Conjugated
100µl 0.5mg/ml  $395.00

TPM3 Antibody (aa6-248, FITC) LS-C694786
Rabbit Polyclonal (IgG) to Mouse TPM3
Mouse
IHC WB
FITC Conjugated
20µl  $215.00; 100µl  $285.00; 200µl  $335.00; 1ml  $650.00; 10ml  $2,580.00
Western blot of TPM3 antibody.
Western blot of TPM3 antibody.

TPM3 Antibody (aa6-248, Cy3) LS-C703484
Rabbit Polyclonal (IgG) to Mouse TPM3
Mouse
IHC WB
Cy3 Conjugated
20µl  $245.00; 100µl  $365.00; 200µl  $445.00; 1ml  $1,080.00; 10ml  $4,320.00
Western blot of TPM3 antibody.
Western blot of TPM3 antibody.

TPM3 Antibody (aa6-248, APC) LS-C718318
Rabbit Polyclonal (IgG) to Mouse TPM3
Mouse
IHC WB
APC Conjugated
20µl  $225.00; 100µl  $315.00; 200µl  $375.00; 1ml  $815.00; 10ml  $5,010.00
Western blot of TPM3 antibody.
Western blot of TPM3 antibody.

TPM3 Antibody (aa6-248, PE) LS-C726568
Rabbit Polyclonal (IgG) to Mouse TPM3
Mouse
IHC WB
PE Conjugated
20µl  $215.00; 100µl  $285.00; 200µl  $335.00; 1ml  $650.00; 10ml  $2,580.00
Western blot of TPM3 antibody.
Western blot of TPM3 antibody.

TPM3 Antibody (aa6-248, APC, Cy7) LS-C735495
Rabbit Polyclonal (IgG) to Mouse TPM3
Mouse
IHC WB
APC, Cy7 Conjugated
20µl  $285.00; 100µl  $465.00; 200µl  $650.00; 1ml  $1,620.00; 10ml  $6,480.00
Western blot of TPM3 antibody.
Western blot of TPM3 antibody.

TPM3 Antibody LS-C192467
Rabbit Polyclonal to Human TPM3
Mouse, Rat, Human
IHC WB
Unconjugated
100µl  $385.00
Western blot of TPM3 pAb in extracts from 293T and A431 cells.
Western blot of TPM3 pAb in extracts from 293T and A431 cells.

TPM3 Antibody (aa1-285) LS-C373144
Rabbit Polyclonal (IgG) to Human TPM3
Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $530.00; 10ml 0.5mg/ml  $2,100.00
Western blot of TPM3 antibody.
Western blot of TPM3 antibody.

TPM3 Antibody (aa1-285, Biotin) LS-C423169
Rabbit Polyclonal (IgG) to Human TPM3
Human
ICC WB
Biotin Conjugated
100µl 0.5mg/ml  $375.00

TPM3 Antibody (aa1-285, Biotin) LS-C687878
Rabbit Polyclonal (IgG) to Human TPM3
Human
IHC WB
Biotin Conjugated
20µl  $205.00; 100µl  $265.00; 200µl  $315.00; 1ml  $575.00; 10ml  $2,310.00
Western blot of TPM3 antibody.
Western blot of TPM3 antibody.

TPM3 Antibody (aa1-285, FITC) LS-C423172
Rabbit Polyclonal (IgG) to Human TPM3
Human
ICC WB
FITC Conjugated
100µl 0.5mg/ml  $395.00

TPM3 Antibody (aa1-285, Cy3) LS-C703483
Rabbit Polyclonal (IgG) to Human TPM3
Human
IHC WB
Cy3 Conjugated
20µl  $245.00; 100µl  $355.00; 200µl  $445.00; 1ml  $1,050.00; 10ml  $4,200.00
Western blot of TPM3 antibody.
Western blot of TPM3 antibody.

TPM3 Antibody LS-C748600
Rabbit Polyclonal (IgG) to Human TPM3
Mouse, Human
IHC WB
Unconjugated
50µl  $235.00
Immunohistochemistry of paraffin-embedded mouse heart using TPM3 antibody at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using TPM3 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking.
Immunohistochemistry of paraffin-embedded mouse heart using TPM3 antibody at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using TPM3 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking.

TPM3 Antibody (clone 1649CT306.29.13) LS-C757641
Mouse Monoclonal [clone 1649CT306.29.13] (IgG1,k) to Human TPM3
Mouse, Human
ELISA WB
Unconjugated
50µl  $215.00; 200µl  $325.00
All lanes: Anti-TPM3 Antibody at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: NIH/3T3 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 33 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
All lanes: Anti-TPM3 Antibody at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: NIH/3T3 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 33 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Showing 1-25 of 37 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

Get Social With Us!
Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy