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TPI1 / TPI

triosephosphate isomerase 1

TPI1 / TPI encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants.

Gene Name: triosephosphate isomerase 1
Synonyms: TPI1, Triose-phosphate isomerase, Triosephosphate isomerase, TPI, Triosephosphate isomerase 1, TIM
Target Sequences: NM_000365 NP_000356.1 P60174

Publications (4)

1
Identification of differentially regulated proteins in a patient with Leber's Congenital Amaurosis--a proteomic study. Vorum H, stergaard M, Rice GE, Honor B, Bek T. Proteome science. 2007 5:5. [PubMed:17326818] [PMC:PMC1821315] Related Antibodies: LS-B2611.
2
Identification of differentially expressed proteins in spontaneous thymic lymphomas from knockout mice with deletion of p53. Honor B, Buus S, Classon MH. Proteome science. 2008 6:18. (WB; Mouse) [PubMed:18544163] [PMC:PMC2491604] Related Antibodies: LS-B2611.
3
Different Polar Metabolites and Protein Profiles between High- and Low-Quality Japanese Ginjo Sake. Takahashi K, Kohno H. PloS one. 2016 11:e0150524. (IHC; Yeast) [Full Text Article] [PubMed:26939054] [PMC:PMC4777507] Related Antibodies: LS-C147663.
4
Context-dependent deposition and regulation of mRNAs in P-bodies. Wang C, Schmich F, Srivatsa S, Weidner J, Beerenwinkel N, Spang A. eLife. 2018 7: (ID; Yeast) [Full Text Article] [PubMed:29297464] Related Antibodies: LS-C147665.
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Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
TPI1 / TPI (8)
No (8)
6His, N-terminus (2)
GST (1)
His (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (7)
293T Cells (1)
E. coli (4)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (2)
Low endotoxin level (2)
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E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
28.8kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
TPI1 / TPI Protein - Purified recombinant protein TPI1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
26.5 kDa
20 µg/$1,107
TPI1 / TPI Protein - 12.5% SDS-PAGE of human TPI1 stained with Coomassie Blue
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Wheat Germ Extract
GST
53.13 kDa
10 µg/$479; 25 µg/$670
TPI1 / TPI Protein - Recombinant  Triosephosphate Isomerase 1 By SDS-PAGE
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E. coli
His-T7
34.5 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
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E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
28.8 kDa
10 µg/$344; 50 µg/$584
TPI1 / TPI Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
26.5 kDa
100 µg/$494
TPI1 / TPI Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
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293T Cells
Myc-DDK (Flag)
26.5 kDa
20 µg/$150
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).