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TPI1 / TPI

triosephosphate isomerase 1

TPI1 / TPI encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants.

Gene Name:	triosephosphate isomerase 1
Synonyms:	TPI1, Triose-phosphate isomerase, Triosephosphate isomerase, TPI, Triosephosphate isomerase 1, TIM
Target Sequences:	NM_000365 NP_000356.1 P60174

Publications (4)

Identification of differentially regulated proteins in a patient with Leber's Congenital Amaurosis--a proteomic study. Vorum H, stergaard M, Rice GE, Honor B, Bek T. Proteome science. 2007 5:5. [PubMed:17326818] [PMC:PMC1821315] Related Antibodies: LS-B2611.

Identification of differentially expressed proteins in spontaneous thymic lymphomas from knockout mice with deletion of p53. Honor B, Buus S, Classon MH. Proteome science. 2008 6:18. (WB; Mouse) [PubMed:18544163] [PMC:PMC2491604] Related Antibodies: LS-B2611.

Different Polar Metabolites and Protein Profiles between High- and Low-Quality Japanese Ginjo Sake. Takahashi K, Kohno H. PloS one. 2016 11:e0150524. (IHC; Yeast) [Full Text Article] [PubMed:26939054] [PMC:PMC4777507] Related Antibodies: LS-C147663.

Context-dependent deposition and regulation of mRNAs in P-bodies. Wang C, Schmich F, Srivatsa S, Weidner J, Beerenwinkel N, Spang A. eLife. 2018 7: (ID; Yeast) [Full Text Article] [PubMed:29297464] Related Antibodies: LS-C147665.

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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