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TPH2

tryptophan hydroxylase 2

TPH2 encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.

Gene Name: tryptophan hydroxylase 2
Synonyms: TPH2, ADHD7, NTPH, Tryptophan hydroxylase 2, Tryptophan 5-hydroxylase 2, Tryptophan 5-monooxygenase 2
Target Sequences: NM_173353 NP_775489.2 Q8IWU9

Publications (1)

1
Activation of glucagon-like peptide-1 receptors reduces the acquisition of aggression-like behaviors in male mice. Jesper Vestlund, Qian Zhang, Olesya T Shevchouk, Daniel Hovey, Lundström Sebastian, Lars Westberg, Elisabet Jerlhag. Translational psychiatry. 2022 October;12:445. [Full Text Article] [PubMed:36229445] [PMC:PMC9561171] Related Antibodies: LS-C346253.

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ELISA Kits (9)
Cell-Based (1)
Custom (2)
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TPH2 (9)
Human (4)
Mouse (3)
Rat (4)
96-Well Microplate (1)
96-Well Strip Plate (8)
No (9)
Adherent Cell Cultures (1)
Cell Lysates (2)
Plasma (4)
Serum (4)
Tissue Homogenates (5)
TPH2 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$854
TPH2 ELISA Kit
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Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
TPH2 ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
TPH2 ELISA Kit
Select
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
TPH2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
TPH2 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$958
TPH2 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$834
TPH2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$893
TPH2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).