TP63 / p63

tumor protein p63

Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.

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Products

Proteins (8)

Type

Over-Expression Lysate (5)

Recombinant (3)

Target

TP63 / p63 (8)

Application

SDS-PAGE (1)

Publications

No (8)

Tag

His-GST (1)

His-GST, N-terminus (1)

Myc-DDK (Flag) (6)

Species

Human (8)

Source

293T Cells (5)

Baculovirus (2)

HEK 293 Cells (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (2)

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Human TP63 / p63 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69398

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

76.6 kDa

Price:

20 µg/$1,107

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Human TP63 / p63 Protein (Recombinant His-GST, N-terminus) (Met1-Glu680) - LS-G50783

Source:

Baculovirus

Tag:

His-GST, N-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human TP63/GST chimera consists of 917 amino acids and has a calculated molecular mass of 105 kDa. It migrates as an approximately 125 kDa band in SDS-PAGE under reducing conditions.

Price:

100 µg/$480

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Human TP63 / p63 Protein (Recombinant His-GST) (Met1-Glu680) - LS-G97977

Source:

Baculovirus

Tag:

His-GST

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

105 kDa

Price:

100 µg/$843

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Human TP63 / p63 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84523

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

65.6 kDa

Price:

20 µg/$150

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Human TP63 / p63 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84524

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

62.3 kDa

Price:

20 µg/$150

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Human TP63 / p63 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84525

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55.5 kDa

Price:

20 µg/$150

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Human TP63 / p63 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84526

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.5 kDa

Price:

20 µg/$150

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Human TP63 / p63 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84527

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

76.6 kDa

Price:

20 µg/$150

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