TP63 / p63

tumor protein p63

Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.

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Products

ELISA Kits (16)

Type

Cell-Based (1)

Cell-Based Phosphorylation (2)

Custom (1)

DNA Binding (1)

Sandwich (10)

Sandwich CLIA (1)

Target

TP63 / p63 (16)

Reactivity

Human (10)

Mouse (4)

Rat (2)

Chicken (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Sheep (1)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (5)

96-Well Strip Plate (9)

Publications

No (16)

Sample Type

Adherent Cell Cultures (3)

Cell Lysates (2)

Nuclear Lysates (1)

Plasma (4)

Serum (4)

Tissue Homogenates (3)

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Human TP63 / p63 (Sandwich ELISA) ELISA Kit - LS-F35099

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human TP63 / p63 (CLIA) ELISA Kit - LS-F30312

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Mouse/Human/Rat TP63 / p63 (Cell-Based ELISA) ELISA Kit - LS-F2214

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

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Human TP63 / p63 (Sandwich ELISA) ELISA Kit - LS-F21241

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Human TP63 / p63 (Sandwich ELISA) ELISA Kit - LS-F27288

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

250 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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Chicken TP63 / p63 (Sandwich ELISA) ELISA Kit - LS-F48874

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Monkey TP63 / p63 (Sandwich ELISA) ELISA Kit - LS-F48876

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Rabbit TP63 / p63 (Sandwich ELISA) ELISA Kit - LS-F48878

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Porcine TP63 / p63 (Sandwich ELISA) ELISA Kit - LS-F48877

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Sheep TP63 / p63 (Sandwich ELISA) ELISA Kit - LS-F48879

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$760

Select

Human TP63 / p63 (Custom ELISA) ELISA Kit - LS-F50678

Type:

Custom

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$672

Select

Human TP63 / p63 (Sandwich ELISA) ELISA Kit - LS-F6596

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$834

Select

Mouse TP63 / p63 (Sandwich ELISA) ELISA Kit - LS-F8900

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$854

Select

Mouse/Human/Rat Phospho-TP63 / p63 (Ser395) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1752

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

Select

Human Phospho-TP63 / p63 (Ser455) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1268

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

Select

Mouse/Human TP63 / p63 (DNA-Binding ELISA) ELISA Kit - LS-F902

Type:

DNA Binding

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Nuclear Lysates

Price:

1 Plate/$694

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