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Unfortunately, the antibody (ID:92287) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



TP53BP1 / 53BP1

tumor protein p53 binding protein 1

Tumor protein p53 binding protein 1 binds to the central domain of p53 required for site-specific DNA binding thus inhibiting the ability of p53 to bind DNA. TP53BP1 also functions as a checkpoint protein with properties of a DNA double-strand break sensor. It is a putative substrate of ATM kinase and is phosphorylated in response to DNA damage and localizes to sites of double-strand breaks.

Gene Name: tumor protein p53 binding protein 1
Synonyms: TP53BP1, 53BP1, p202, p53-binding protein 1, p53-binding protein 53bp1, p53BP1
Target Sequences: NM_005657 NP_005648.1 Q12888

Publications (102)

1
Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint. Silverman J, Takai H, Buonomo SB, Eisenhaber F, de Lange T. Genes & development. 2004 18:2108-19. [PubMed:15342490] [PMC:PMC515289]
2
Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres. Hockemeyer D, Daniels JP, Takai H, de Lange T. Cell. 2006 126:63-77. [PubMed:16839877]
3
Leukocyte DNA damage after multi-detector row CT: a quantitative biomarker of low-level radiation exposure. Rothkamm K, Balroop S, Shekhdar J, Fernie P, Goh V. Radiology. 2007 242:244-51. [PubMed:17185671]
4
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1. Denchi EL, de Lange T. Nature. 2007 448:1068-71. [PubMed:17687332]
5
Regulation of phosphoglucose isomerase/autocrine motility factor activities by the poly(ADP-ribose) polymerase family-14. Yanagawa T, Funasaka T, Tsutsumi S, Hu H, Watanabe H, Raz A. Cancer research. 2007 67:8682-9. [PubMed:17875708]
6
Global chromatin compaction limits the strength of the DNA damage response. Murga M, Jaco I, Fan Y, Soria R, Martinez-Pastor B, Cuadrado M, Yang SM, Blasco MA, Skoultchi AI, Fernandez-Capetillo O. The Journal of cell biology. 2007 178:1101-8. [PubMed:17893239] [PMC:PMC2064646]
7
ATR signaling can drive cells into senescence in the absence of DNA breaks. Toledo LI, Murga M, Gutierrez-Martinez P, Soria R, Fernandez-Capetillo O. Genes & development. 2008 22:297-302. [PubMed:18245444] [PMC:PMC2216689]
8
Role of ATM in the telomere response to the G-quadruplex ligand 360A. Pennarun G, Granotier C, Hoffschir F, Mandine E, Biard D, Gauthier LR, Boussin FD. Nucleic acids research. 2008 36:1741-54. [PubMed:18263609] [PMC:PMC2275132]
9
Cell cycle control of telomere protection and NHEJ revealed by a ts mutation in the DNA-binding domain of TRF2. Konishi A, de Lange T. Genes & development. 2008 22:1221-30. [PubMed:18451109] [PMC:PMC2335317]
10
Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication. Ibarra A, Schwob E, Mndez J. Proceedings of the National Academy of Sciences of the United States of America. 2008 105:8956-61. [PubMed:18579778] [PMC:PMC2449346]
11
Transcription-coupled DNA double-strand breaks are mediated via the nucleotide excision repair and the Mre11-Rad50-Nbs1 complex. Guirouilh-Barbat J, Redon C, Pommier Y. Molecular biology of the cell. 2008 19:3969-81. [PubMed:18632984] [PMC:PMC2526702]
12
A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse. Schotta G, Sengupta R, Kubicek S, Malin S, Kauer M, Calln E, Celeste A, Pagani M, Opravil S, De La Rosa-Velazquez IA, Espejo A, Bedford MT, Nussenzweig A, Busslinger M, Jenuwein T. Genes & development. 2008 22:2048-61. [PubMed:18676810] [PMC:PMC2492754]
13
ATM acts downstream of ATR in the DNA damage response signaling of bystander cells. Burdak-Rothkamm S, Rothkamm K, Prise KM. Cancer research. 2008 68:7059-65. [PubMed:18757420] [PMC:PMC2528059]
14
Impaired DNA double-strand break repair contributes to chemoresistance in HIF-1 alpha-deficient mouse embryonic fibroblasts. Wirthner R, Wrann S, Balamurugan K, Wenger RH, Stiehl DP. Carcinogenesis. 2008 29:2306-16. (WB; Mouse) [PubMed:18842680]
15
Functional dissection of human and mouse POT1 proteins. Palm W, Hockemeyer D, Kibe T, de Lange T. Molecular and cellular biology. 2009 29:471-82. [PubMed:18955498] [PMC:PMC2612509]
16
Death receptor-induced activation of the Chk2- and histone H2AX-associated DNA damage response pathways. Solier S, Sordet O, Kohn KW, Pommier Y. Molecular and cellular biology. 2009 29:68-82. [PubMed:18955500] [PMC:PMC2612481]
17
Rad50 is dispensable for the maintenance and viability of postmitotic tissues. Adelman CA, De S, Petrini JH. Molecular and cellular biology. 2009 29:483-92. [PubMed:19001091] [PMC:PMC2612516]
18
HPV-16 E7 reveals a link between DNA replication stress, fanconi anemia D2 protein, and alternative lengthening of telomere-associated promyelocytic leukemia bodies. Spardy N, Duensing A, Hoskins EE, Wells SI, Duensing S. Cancer research. 2008 68:9954-63. [PubMed:19047177] [PMC:PMC2597390]
19
Sister telomeres rendered dysfunctional by persistent cohesion are fused by NHEJ. Hsiao SJ, Smith S. The Journal of cell biology. 2009 184:515-26. [PubMed:19221198] [PMC:PMC2654126]
20
Heat-induced perturbations of DNA damage signaling pathways are modulated by molecular chaperones. Laszlo A, Fleischer I. Cancer research. 2009 69:2042-9. [PubMed:19244134]
21
MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks. Shao G, Patterson-Fortin J, Messick TE, Feng D, Shanbhag N, Wang Y, Greenberg RA. Genes & development. 2009 23:740-54. [PubMed:19261746] [PMC:PMC2661612]
22
A mouse PRMT1 null allele defines an essential role for arginine methylation in genome maintenance and cell proliferation. Yu Z, Chen T, Hbert J, Li E, Richard S. Molecular and cellular biology. 2009 29:2982-96. [PubMed:19289494] [PMC:PMC2681996]
23
Induction of glutathione-dependent DNA double-strand breaks by the novel anticancer drug brostallicin. Guirouilh-Barbat J, Zhang YW, Pommier Y. Molecular cancer therapeutics. 2009 8:1985-94. [PubMed:19584235] [PMC:PMC2760303]
24
Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway. Rizzo A, Salvati E, Porru M, D'Angelo C, Stevens MF, D'Incalci M, Leonetti C, Gilson E, Zupi G, Biroccio A. Nucleic acids research. 2009 37:5353-64. [PubMed:19596811] [PMC:PMC2760797]
25
Loss of histone deacetylase 4 causes segregation defects during mitosis of p53-deficient human tumor cells. Cadot B, Brunetti M, Coppari S, Fedeli S, de Rinaldis E, Dello Russo C, Gallinari P, De Francesco R, Steinkhler C, Filocamo G. Cancer research. 2009 69:6074-82. [PubMed:19622775]
26
Intercellular communication of cellular stress monitored by gamma-H2AX induction. Dickey JS, Baird BJ, Redon CE, Sokolov MV, Sedelnikova OA, Bonner WM. Carcinogenesis. 2009 30:1686-95. [PubMed:19651821] [PMC:PMC2757548]
27
Cell cycle-dependent role of MRN at dysfunctional telomeres: ATM signaling-dependent induction of nonhomologous end joining (NHEJ) in G1 and resection-mediated inhibition of NHEJ in G2. Dimitrova N, de Lange T. Molecular and cellular biology. 2009 29:5552-63. [PubMed:19667071] [PMC:PMC2756883]
28
The mre11 complex and the response to dysfunctional telomeres. Attwooll CL, Akpinar M, Petrini JH. Molecular and cellular biology. 2009 29:5540-51. [PubMed:19667076] [PMC:PMC2756889]
29
Human papillomavirus 16 E7 oncoprotein attenuates DNA damage checkpoint control by increasing the proteolytic turnover of claspin. Spardy N, Covella K, Cha E, Hoskins EE, Wells SI, Duensing A, Duensing S. Cancer research. 2009 69:7022-9. [PubMed:19706760] [PMC:PMC2737077]
30
Telomeric DNA mediates de novo PML body formation. Brouwer AK, Schimmel J, Wiegant JC, Vertegaal AC, Tanke HJ, Dirks RW. Molecular biology of the cell. 2009 20:4804-15. [PubMed:19793919] [PMC:PMC2777109]
31
Mammalian Rif1 contributes to replication stress survival and homology-directed repair. Buonomo SB, Wu Y, Ferguson D, de Lange T. The Journal of cell biology. 2009 187:385-98. [PubMed:19948482] [PMC:PMC2779251]
32
Telomere protection by TPP1 is mediated by POT1a and POT1b. Kibe T, Osawa GA, Keegan CE, de Lange T. Molecular and cellular biology. 2010 30:1059-66. [PubMed:19995905] [PMC:PMC2815557]
33
The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination. Ramachandran S, Chahwan R, Nepal RM, Frieder D, Panier S, Roa S, Zaheen A, Durocher D, Scharff MD, Martin A. Proceedings of the National Academy of Sciences of the United States of America. 2010 107:809-14. (ICC, WB; Mouse) [PubMed:20080757] [PMC:PMC2818930]
34
Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair. Moon SH, Lin L, Zhang X, Nguyen TA, Darlington Y, Waldman AS, Lu X, Donehower LA. The Journal of biological chemistry. 2010 285:12935-47. [PubMed:20118229] [PMC:PMC2857113]
35
Selective targeting of radiation-resistant tumor-initiating cells. Zhang M, Atkinson RL, Rosen JM. Proceedings of the National Academy of Sciences of the United States of America. 2010 107:3522-7. (ICC, Flo; Mouse) [PubMed:20133717] [PMC:PMC2840501]
36
Differential requirement for H2AX and 53BP1 in organismal development and genome maintenance in the absence of poly(ADP)ribosyl polymerase 1. Orsburn B, Escudero B, Prakash M, Gesheva S, Liu G, Huso DL, Franco S. Molecular and cellular biology. 2010 30:2341-52. [PubMed:20231360] [PMC:PMC2863712]
37
Ionizing radiation-induced long-term expression of senescence markers in mice is independent of p53 and immune status. Le ON, Rodier F, Fontaine F, Coppe JP, Campisi J, DeGregori J, Laverdire C, Kokta V, Haddad E, Beausjour CM. Aging cell. 2010 9:398-409. [PubMed:20331441] [PMC:PMC2894262]
38
LIM-domain proteins TRIP6 and LPP associate with shelterin to mediate telomere protection. Sheppard SA, Loayza D. Aging. 2010 2:432-44. [PubMed:20634563] [PMC:PMC2933890]
39
Substance P inhibits natural killer cell cytotoxicity through the neurokinin-1 receptor. Monaco-Shawver L, Schwartz L, Tuluc F, Guo CJ, Lai JP, Gunnam SM, Kilpatrick LE, Banerjee PP, Douglas SD, Orange JS. Journal of leukocyte biology. 2011 89:113-25. [PubMed:20940324] [PMC:PMC3004520]
40
The p53/p21(WAF/CIP) pathway mediates oxidative stress and senescence in dyskeratosis congenita cells with telomerase insufficiency. Westin ER, Aykin-Burns N, Buckingham EM, Spitz DR, Goldman FD, Klingelhutz AJ. Antioxidants & redox signaling. 2011 14:985-97. (ICC; Human) [PubMed:21087144] [PMC:PMC3043957]
41
DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion. Rodier F, Muoz DP, Teachenor R, Chu V, Le O, Bhaumik D, Copp JP, Campeau E, Beausjour CM, Kim SH, Davalos AR, Campisi J. Journal of cell science. 2011 124:68-81. [PubMed:21118958] [PMC:PMC3001408]
42
Poly(ADP-ribose) polymerase and XPF-ERCC1 participate in distinct pathways for the repair of topoisomerase I-induced DNA damage in mammalian cells. Zhang YW, Regairaz M, Seiler JA, Agama KK, Doroshow JH, Pommier Y. Nucleic acids research. 2011 39:3607-20. [PubMed:21227924] [PMC:PMC3089458]
43
Astrocyte dysfunction associated with cerebellar attrition in a Nijmegen breakage syndrome animal model. Galron R, Gruber R, Lifshitz V, Lu H, Kirshner M, Ziv N, Wang ZQ, Shiloh Y, Barzilai A, Frenkel D. Journal of molecular neuroscience : MN. 2011 45:202-11. (ICC, IHC, IHC-P; Mouse) [PubMed:21279473]
44
The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection. Coleman KA, Greenberg RA. The Journal of biological chemistry. 2011 286:13669-80. [PubMed:21335604] [PMC:PMC3075711]
45
The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance. Mortensen M, Soilleux EJ, Djordjevic G, Tripp R, Lutteropp M, Sadighi-Akha E, Stranks AJ, Glanville J, Knight S, Jacobsen SE, Kranc KR, Simon AK. The Journal of experimental medicine. 2011 208:455-67. [PubMed:21339326] [PMC:PMC3058574]
46
Replication stress induces 53BP1-containing OPT domains in G1 cells. Harrigan JA, Belotserkovskaya R, Coates J, Dimitrova DS, Polo SE, Bradshaw CR, Fraser P, Jackson SP. The Journal of cell biology. 2011 193:97-108. [PubMed:21444690] [PMC:PMC3082192]
47
HP1alpha recruitment to DNA damage by p150CAF-1 promotes homologous recombination repair. Baldeyron C, Soria G, Roche D, Cook AJ, Almouzni G. The Journal of cell biology. 2011 193:81-95. (ICC, WB; Mouse, Human) [PubMed:21464229] [PMC:PMC3082177]
48
Matrix metalloproteinases and their inhibitors and inducer in gestational trophoblastic diseases and normal placenta. Singh M, Kindelberger D, Nagymanyoki Z, Ng SW, Quick CM, Elias KM, Yamamoto H, Fichorova R, Fulop V, Berkowitz RS. Gynecologic oncology. 2011 122:178-82. (IHC-P; Human) [PubMed:21514631]
49
Microsatellite instability in pediatric high grade glioma is associated with genomic profile and differential target gene inactivation. Viana-Pereira M, Lee A, Popov S, Bax DA, Al-Sarraj S, Bridges LR, Stvale JN, Hargrave D, Jones C, Reis RM. PloS one. 2011 6:e20588. (ICC; Human) [PubMed:21637783] [PMC:PMC3102740]
50
Survivin inhibition and DNA double-strand break repair: a molecular mechanism to overcome radioresistance in glioblastoma. Reichert S, Rdel C, Mirsch J, Harter PN, Tomicic MT, Mittelbronn M, Kaina B, Rdel F. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2011 101:51-8. (ICC, WB; Human) [PubMed:21852011]
51
DNA-damage response and repair activities at uncapped telomeres depend on RNF8. Peuscher MH, Jacobs JJ. Nature cell biology. 2011 13:1139-45. [PubMed:21857671]
52
A stress response pathway regulates DNA damage through 2-adrenoreceptors and -arrestin-1. Hara MR, Kovacs JJ, Whalen EJ, Rajagopal S, Strachan RT, Grant W, Towers AJ, Williams B, Lam CM, Xiao K, Shenoy SK, Gregory SG, Ahn S, Duckett DR, Lefkowitz RJ. Nature. 2011 477:349-53. [PubMed:21857681]
53
Oncogenic YAP promotes radioresistance and genomic instability in medulloblastoma through IGF2-mediated Akt activation. Fernandez-L A, Squatrito M, Northcott P, Awan A, Holland EC, Taylor MD, Nahl Z, Kenney AM. Oncogene. 2012 31:1923-37. [PubMed:21874045] [PMC:PMC3583298]
54
DNA damage response is suppressed by the high cyclin-dependent kinase 1 activity in mitotic mammalian cells. Zhang W, Peng G, Lin SY, Zhang P. The Journal of biological chemistry. 2011 286:35899-905. [PubMed:21878640] [PMC:PMC3195557]
55
53BP1 contributes to a robust genomic stability in human fibroblasts. Fink LS, Roell M, Caiazza E, Lerner C, Stamato T, Hrelia S, Lorenzini A, Sell C. Aging. 2011 3:836-45. [PubMed:21931182] [PMC:PMC3227449]
56
Pteridium aquilinum and its ptaquiloside toxin induce DNA damage response in gastric epithelial cells, a link with gastric carcinogenesis. Gomes J, Magalhes A, Michel V, Amado IF, Aranha P, Ovesen RG, Hansen HC, Grtner F, Reis CA, Touati E. Toxicological sciences : an official journal of the Society of Toxicology. 2012 126:60-71. [PubMed:22143989]
57
WRN helicase regulates the ATR-CHK1-induced S-phase checkpoint pathway in response to topoisomerase-I-DNA covalent complexes. Patro BS, Frhlich R, Bohr VA, Stevnsner T. Journal of cell science. 2011 124:3967-79. [PubMed:22159421] [PMC:PMC3244981]
58
IL-7R deficiency in p53null mice exacerbates thymocyte telomere erosion and lymphomagenesis. Kibe R, Zhang S, Guo D, Marrero L, Tsien F, Rodriguez P, Khan S, Zieske A, Huang J, Li W, Durum SK, Iwakuma T, Cui Y. Cell death and differentiation. 2012 19:1139-51. (ICC; Mouse) [PubMed:22281704] [PMC:PMC3374079]
59
Radiation-inducible immunotherapy for cancer: senescent tumor cells as a cancer vaccine. Meng Y, Efimova EV, Hamzeh KW, Darga TE, Mauceri HJ, Fu YX, Kron SJ, Weichselbaum RR. Molecular therapy : the journal of the American Society of Gene Therapy. 2012 20:1046-55. [PubMed:22334019] [PMC:PMC3345982]
60
RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites. Mallette FA, Mattiroli F, Cui G, Young LC, Hendzel MJ, Mer G, Sixma TK, Richard S. The EMBO journal. 2012 31:1865-78. [PubMed:22373579] [PMC:PMC3343333]
61
Shelterin dysfunction and p16(INK4a)-mediated growth inhibition in HIV-1-specific CD8 T cells. Lichterfeld M, Cung T, Seiss K, Rosenberg ES, Pereyra F, Yu XG. Journal of virology. 2012 86:5533-40. (ICC; Human) [PubMed:22398292] [PMC:PMC3347267]
62
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation. Fumagalli M, Rossiello F, Clerici M, Barozzi S, Cittaro D, Kaplunov JM, Bucci G, Dobreva M, Matti V, Beausejour CM, Herbig U, Longhese MP, d'Adda di Fagagna F. Nature cell biology. 2012 14:355-65. (ICC; Human) [PubMed:22426077]
63
Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence. Hewitt G, Jurk D, Marques FD, Correia-Melo C, Hardy T, Gackowska A, Anderson R, Taschuk M, Mann J, Passos JF. Nature communications. 2012 3:708. (ICC; Human) [PubMed:22426229] [PMC:PMC3292717]
64
Chk1 suppresses bypass of mitosis and tetraploidization in p53-deficient cancer cells. Wilsker D, Chung JH, Bunz F. Cell cycle (Georgetown, Tex.). 2012 11:1564-72. (ICC, WB; Human) [PubMed:22433954] [PMC:PMC3341228]
65
The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombination. Chahwan R, van Oers JM, Avdievich E, Zhao C, Edelmann W, Scharff MD, Roa S. The Journal of experimental medicine. 2012 209:671-8. (WB; Mouse) [PubMed:22451719] [PMC:PMC3328365]
66
The activation of DNA damage detection and repair responses in cleavage-stage rat embryos by a damaged paternal genome. Grenier L, Robaire B, Hales BF. Toxicological sciences : an official journal of the Society of Toxicology. 2012 127:555-66. (ICC; Rat) [PubMed:22454429] [PMC:PMC3355317]
67
A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure. Luijsterburg MS, Acs K, Ackermann L, Wiegant WW, Bekker-Jensen S, Larsen DH, Khanna KK, van Attikum H, Mailand N, Dantuma NP. The EMBO journal. 2012 31:2511-27. (ICC; Mouse) [PubMed:22531782] [PMC:PMC3365417]
68
Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions. Suram A, Kaplunov J, Patel PL, Ruan H, Cerutti A, Boccardi V, Fumagalli M, Di Micco R, Mirani N, Gurung RL, Hande MP, d'Adda di Fagagna F, Herbig U. The EMBO journal. 2012 31:2839-51. (ICC, IHC; Human) [PubMed:22569128] [PMC:PMC3395091]
69
Metabolism of Cr(VI) by ascorbate but not glutathione is a low oxidant-generating process. Wong V, Armknecht S, Zhitkovich A. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). 2012 26:192-6. (ICC; Human) [PubMed:22572042] [PMC:PMC3380165]
70
Cisplatin resistance induced in germ cell tumour cells is due to reduced susceptibility towards cell death but not to altered DNA damage induction or repair. Fenske AE, Glaesener S, Bokemeyer C, Thomale J, Dahm-Daphi J, Honecker F, Dartsch DC. Cancer letters. 2012 324:171-8. (ICC; Human) [PubMed:22613583]
71
mRNA decay factor AUF1 maintains normal aging, telomere maintenance, and suppression of senescence by activation of telomerase transcription. Pont AR, Sadri N, Hsiao SJ, Smith S, Schneider RJ. Molecular cell. 2012 47:15-May. (ICC; Mouse) [PubMed:22633954]
72
Molecular basis of Lys-63-linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin-conjugating enzyme UBC13. Sato Y, Yamagata A, Goto-Ito S, Kubota K, Miyamoto R, Nakada S, Fukai S. The Journal of biological chemistry. 2012 287:25860-8. (ICC; Human) [PubMed:22679021] [PMC:PMC3406671]
73
Autocrine regulation of -irradiation-induced DNA damage response via extracellular nucleotides-mediated activation of P2Y6 and P2Y12 receptors. Nishimaki N, Tsukimoto M, Kitami A, Kojima S. DNA repair. 2012 11:657-65. (ICC; Human) [PubMed:22682873]
74
Telomere-driven tetraploidization occurs in human cells undergoing crisis and promotes transformation of mouse cells. Davoli T, de Lange T. Cancer cell. 2012 21:765-76. (ICC; Human) [PubMed:22698402] [PMC:PMC3376354]
75
Targeting radiation-resistant hypoxic tumour cells through ATR inhibition. Pires IM, Olcina MM, Anbalagan S, Pollard JR, Reaper PM, Charlton PA, McKenna WG, Hammond EM. British journal of cancer. 2012 107:291-9. (ICC; Human) [PubMed:22713662] [PMC:PMC3394988]
76
Kruppel-associated Box (KRAB)-associated co-repressor (KAP-1) Ser-473 phosphorylation regulates heterochromatin protein 1 (HP1-) mobilization and DNA repair in heterochromatin. Bolderson E, Savage KI, Mahen R, Pisupati V, Graham ME, Richard DJ, Robinson PJ, Venkitaraman AR, Khanna KK. The Journal of biological chemistry. 2012 287:28122-31. (ICC; Human) [PubMed:22715096] [PMC:PMC3431694]
77
Site-specific DICER and DROSHA RNA products control the DNA-damage response. Francia S, Michelini F, Saxena A, Tang D, de Hoon M, Anelli V, Mione M, Carninci P, d'Adda di Fagagna F. Nature. 2012 488:231-5. (ICC; Mouse, Human) [PubMed:22722852] [PMC:PMC3442236]
78
Radiobiological effectiveness of laser accelerated electrons in comparison to electron beams from a conventional linear accelerator. Laschinsky L, Baumann M, Beyreuther E, Enghardt W, Kaluza M, Karsch L, Lessmann E, Naumburger D, Nicolai M, Richter C, Sauerbrey R, Schlenvoigt HP, Pawelke J. Journal of radiation research. 2012 53:395-403. (ICC; Human) [PubMed:22739009]
79
Enhanced radiosensitivity of head and neck squamous cell carcinoma cells by 1 integrin inhibition. Eke I, Dickreuter E, Cordes N. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2012 104:235-42. (ICC; Human) [PubMed:22748391]
80
A TRF1-controlled common fragile site containing interstitial telomeric sequences. Bosco N, de Lange T. Chromosoma. 2012 121:465-74. (ICC; Human) [PubMed:22790221] [PMC:PMC3590843]
81
Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway. Lovejoy CA, Li W, Reisenweber S, Thongthip S, Bruno J, de Lange T, De S, Petrini JH, Sung PA, Jasin M, Rosenbluh J, Zwang Y, Weir BA, Hatton C, Ivanova E, Macconaill L, Hanna M, Hahn WC, Lue NF, Reddel RR, Jiao Y, Kinzler K, Vogelstein B, Papadopoulos N,. PLoS genetics. 2012 8:e1002772. (ICC; Human) [PubMed:22829774] [PMC:PMC3400581]
82
Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response. Jurk D, Wang C, Miwa S, Maddick M, Korolchuk V, Tsolou A, Gonos ES, Thrasivoulou C, Saffrey MJ, Cameron K, von Zglinicki T. Aging cell. 2012 11:996-1004. (ICC, IHC-Fr; Mouse) [PubMed:22882466] [PMC:PMC3533793]
83
Three-dimensional invasion of human glioblastoma cells remains unchanged by X-ray and carbon ion irradiation in vitro. Eke I, Storch K, Kstner I, Vehlow A, Faethe C, Mueller-Klieser W, Taucher-Scholz G, Temme A, Schackert G, Cordes N. International journal of radiation oncology, biology, physics. 2012 84:e515-23. (ICC; Human) [PubMed:22901381]
84
DNA damage responses following exposure to modulated radiation fields. Trainor C, Butterworth KT, McGarry CK, McMahon SJ, O'Sullivan JM, Hounsell AR, Prise KM. PloS one. 2012 7:e43326. (ICC; Human) [PubMed:22912853] [PMC:PMC3422245]
85
53BP1 is a haploinsufficient tumor suppressor and protects cells from radiation response in glioma. Squatrito M, Vanoli F, Schultz N, Jasin M, Holland EC. Cancer research. 2012 72:5250-60. (IHC; Mouse) [PubMed:22915756]
86
The autophagy-senescence connection in chemotherapy: must tumor cells (self) eat before they sleep?. Goehe RW, Di X, Sharma K, Bristol ML, Henderson SC, Valerie K, Rodier F, Davalos AR, Gewirtz DA. The Journal of pharmacology and experimental therapeutics. 2012 343:763-78. (ICC; Human) [PubMed:22927544] [PMC:PMC3500537]
87
Ploidy and large-scale genomic instability consistently identify basal-like breast carcinomas with BRCA1/2 inactivation. Popova T, Mani E, Rieunier G, Caux-Moncoutier V, Tirapo C, Dubois T, Delattre O, Sigal-Zafrani B, Bollet M, Longy M, Houdayer C, Sastre-Garau X, Vincent-Salomon A, Stoppa-Lyonnet D, Stern MH. Cancer research. 2012 72:5454-62. (ICC; Human) [PubMed:22933060]
88
Necrosis-like death can engage multiple pro-apoptotic Bcl-2 protein family members. Tischner D, Manzl C, Soratroi C, Villunger A, Krumschnabel G. Apoptosis : an international journal on programmed cell death. 2012 17:1197-209. (ICC; Mouse) [PubMed:22971741]
89
From single-strand breaks to double-strand breaks during S-phase: a new mode of action of the Escherichia coli Cytolethal Distending Toxin. Fedor Y, Vignard J, Nicolau-Travers ML, Boutet-Robinet E, Watrin C, Salles B, Mirey G. Cellular microbiology. 2013 15:15-Jan. (ICC; Human) [PubMed:22978660]
90
SPOC1 modulates DNA repair by regulating key determinants of chromatin compaction and DNA damage response. Mund A, Schubert T, Staege H, Kinkley S, Reumann K, Kriegs M, Fritsch L, Battisti V, Ait-Si-Ali S, Hoffbeck AS, Soutoglou E, Will H. Nucleic acids research. 2012 40:11363-79. (ICC; Human) [PubMed:23034801] [PMC:PMC3526275]
91
Inhibition of ATM blocks the etoposide-induced DNA damage response and apoptosis of resting human T cells. Korwek Z, Sewastianik T, Bielak-Zmijewska A, Mosieniak G, Alster O, Moreno-Villaneuva M, Burkle A, Sikora E. DNA repair. 2012 11:864-73. (ICC; Human) [PubMed:23058634]
92
Alteration/deficiency in activation-3 (Ada3) plays a critical role in maintaining genomic stability. Mirza S, Katafiasz BJ, Kumar R, Wang J, Mohibi S, Jain S, Gurumurthy CB, Pandita TK, Dave BJ, Band H, Band V. Cell cycle (Georgetown, Tex.). 2012 11:4266-74. (WB; Mouse) [PubMed:23095635] [PMC:PMC3524221]
93
RECQ1 is required for cellular resistance to replication stress and catalyzes strand exchange on stalled replication fork structures. Popuri V, Croteau DL, Brosh RM, Bohr VA. Cell cycle (Georgetown, Tex.). 2012 11:4252-65. (ICC; Human) [PubMed:23095637] [PMC:PMC3524220]
94
The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity. Nandakumar J, Bell CF, Weidenfeld I, Zaug AJ, Leinwand LA, Cech TR. Nature. 2012 492:285-9. (ICC; Human) [PubMed:23103865] [PMC:PMC3521872]
95
Primary microcephaly, impaired DNA replication, and genomic instability caused by compound heterozygous ATR mutations. Mokrani-Benhelli H, Gaillard L, Biasutto P, Le Guen T, Touzot F, Vasquez N, Komatsu J, Conseiller E, Pcard C, Gluckman E, Francannet C, Fischer A, Durandy A, Soulier J, de Villartay JP, Cavazzana-Calvo M, Revy P. Human mutation. 2013 34:374-84. (ICC; Human) [PubMed:23111928]
96
Endoglin (CD105) contributes to platinum resistance and is a target for tumor-specific therapy in epithelial ovarian cancer. Ziebarth AJ, Nowsheen S, Steg AD, Shah MM, Katre AA, Dobbin ZC, Han HD, Lopez-Berestein G, Sood AK, Conner M, Yang ES, Landen CN. Clinical cancer research : an official journal of the American Association for Cancer Research. 2013 19:170-82. (ICC, IHC; Mouse) [PubMed:23147994] [PMC:PMC3537868]
97
Impact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaks. Hartlerode AJ, Guan Y, Rajendran A, Ura K, Schotta G, Xie A, Shah JV, Scully R. PloS one. 2012 7:e49211. (ICC; Mouse) [PubMed:23209566] [PMC:PMC3509127]
98
Loss of PIDD limits NF-B activation and cytokine production but not cell survival or transformation after DNA damage. Bock FJ, Krumschnabel G, Manzl C, Peintner L, Tanzer MC, Hermann-Kleiter N, Baier G, Llacuna L, Yelamos J, Villunger A. Cell death and differentiation. 2013 20:546-57. (ICC; Mouse) [PubMed:23238565] [PMC:PMC3595480]
99
The histone methyltransferase MMSET regulates class switch recombination. Pei H, Wu X, Liu T, Yu K, Jelinek DF, Lou Z. Journal of immunology (Baltimore, Md. : 1950). 2013 190:756-63. (WB; Mouse) [PubMed:23241889]
100
The chromatin remodeler p400 ATPase facilitates Rad51-mediated repair of DNA double-strand breaks. Courilleau C, Chailleux C, Jauneau A, Grimal F, Briois S, Boutet-Robinet E, Boudsocq F, Trouche D, Canitrot Y. The Journal of cell biology. 2012 199:1067-81. (ICC; Human) [PubMed:23266955] [PMC:PMC3529529]
101
BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny. Sotiropoulou PA, Karambelas AE, Debaugnies M, Candi A, Bouwman P, Moers V, Revenco T, Rocha AS, Sekiguchi K, Jonkers J, Blanpain C. Genes & development. 2013 27:39-51. (ICC, IHC; Mouse) [PubMed:23271346] [PMC:PMC3553282]
102
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Target Reactivity Applications Host Isotype Clonality Clone Format Epitope Publications Type
TP53BP1 / 53BP1 Rabbit Polyclonal Unconjugated,Biotin Conjugated,DY550 Conjugated,DY488 Conjugated,DY650 Conjugated Human, Mouse IHC-P, ICC, WB,IHC, IHC-P, ICC, WB,IHC, IHC-P, ICC, WB,IHC, IHC-P, ICC, WB,IHC, IHC-P, ICC, WB
5
TP53BP1 / 53BP1 Rabbit Polyclonal Unconjugated Human, Mouse IHC-P, ICC, WB No Primary
Anti-TP53BP1 / 53BP1 Antibody IHC-plus™ LS-B315
Immunohistochemistry Image
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human, Mouse
IHC - Paraffin, ICC, Western blot
Unconjugated
TP53BP1 / 53BP1 Rabbit Polyclonal Biotin Conjugated Human, Mouse IHC, IHC-P, ICC, WB No Primary
Anti-TP53BP1 / 53BP1 Antibody (Biotin) LS-C142822
Immunohistochemistry Image
Immunocytochemistry Image
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human, Mouse
IHC, IHC - Paraffin, ICC, Western blot
Biotin Conjugated
TP53BP1 / 53BP1 Rabbit Polyclonal DY550 Conjugated Human, Mouse IHC, IHC-P, ICC, WB No Primary
Anti-TP53BP1 / 53BP1 Antibody (DY550) LS-C142826
Immunohistochemistry Image
Immunocytochemistry Image
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human, Mouse
IHC, IHC - Paraffin, ICC, Western blot
DY550 Conjugated
TP53BP1 / 53BP1 Rabbit Polyclonal DY488 Conjugated Human, Mouse IHC, IHC-P, ICC, WB No Primary
Anti-TP53BP1 / 53BP1 Antibody (DY488) LS-C142824
Immunohistochemistry Image
Immunocytochemistry Image
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human, Mouse
IHC, IHC - Paraffin, ICC, Western blot
DY488 Conjugated
TP53BP1 / 53BP1 Rabbit Polyclonal DY650 Conjugated Human, Mouse IHC, IHC-P, ICC, WB No Primary
Anti-TP53BP1 / 53BP1 Antibody (DY650) LS-C142823
Immunohistochemistry Image
Immunocytochemistry Image
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human, Mouse
IHC, IHC - Paraffin, ICC, Western blot
DY650 Conjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human IHC-P, WB C-Terminus
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human IHC-P, WB C-Terminus No Primary
Anti-TP53BP1 / 53BP1 Antibody (C-Terminus) IHC-plus™ LS-B1714
Immunohistochemistry Image
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human
IHC - Paraffin, Western blot
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated,Biotin Conjugated,DY550 Conjugated,DY488 Conjugated,DY650 Conjugated Human, Mouse, Rat, Goat, Fish, Primate IHC-P,IHC-P, ICC, IF, WB, Flo,IHC-P, ICC, IF, WB, Flo,IHC-P, ICC, IF, WB, Flo,IHC-P, ICC, IF, WB, Flo aa350-400
5
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat, Goat, Fish, Primate IHC-P aa350-400 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa350-400) IHC-plus™ LS-B6175
Immunohistochemistry Image
Immunofluorescence Image
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human, Mouse, Rat, Goat, Fish, Primate
IHC - Paraffin
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Biotin Conjugated Human, Mouse, Rat, Goat, Fish, Primate IHC-P, ICC, IF, WB, Flo aa350-400 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa350-400, Biotin) LS-C141093
Immunohistochemistry Image
Immunofluorescence Image
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human, Mouse, Rat, Goat, Fish, Primate
IHC - Paraffin, ICC, Immunofluorescence, Western blot, Flow Cytometry
Biotin Conjugated
TP53BP1 / 53BP1 Rabbit Polyclonal DY550 Conjugated Human, Mouse IHC-P, ICC, IF, WB, Flo aa350-400 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa350-400, DY550) LS-C141097
Immunohistochemistry Image
Immunofluorescence Image
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human, Mouse
IHC - Paraffin, ICC, Immunofluorescence, Western blot, Flow Cytometry
DY550 Conjugated
TP53BP1 / 53BP1 Rabbit Polyclonal DY488 Conjugated Human, Mouse IHC-P, ICC, IF, WB, Flo aa350-400 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa350-400, DY488) LS-C141095
Immunohistochemistry Image
Immunofluorescence Image
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human, Mouse
IHC - Paraffin, ICC, Immunofluorescence, Western blot, Flow Cytometry
DY488 Conjugated
TP53BP1 / 53BP1 Rabbit Polyclonal DY650 Conjugated Human, Mouse IHC-P, ICC, IF, WB, Flo aa350-400 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa350-400, DY650) LS-C141094
Immunohistochemistry Image
Immunofluorescence Image
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human, Mouse
IHC - Paraffin, ICC, Immunofluorescence, Western blot, Flow Cytometry
DY650 Conjugated
TP53BP1 / 53BP1 Rabbit Polyclonal Unconjugated Human, Mouse, Rat IHC-P, ICC, IF, WB N-Terminus
1
TP53BP1 / 53BP1 Rabbit Polyclonal Unconjugated Human, Mouse, Rat IHC-P, ICC, IF, WB N-Terminus No Primary
Anti-TP53BP1 / 53BP1 Antibody (N-Terminus) LS-C354111
Immunohistochemistry Image
Immunofluorescence Image
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human, Mouse, Rat
IHC - Paraffin, ICC, Immunofluorescence, Western blot
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit IHC-P, IF, WB, IP, Flo, PLA pSer25
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit IHC-P, IF, WB, IP, Flo, PLA pSer25 No Primary
Anti-TP53BP1 / 53BP1 Antibody (phospho-Ser25) LS-C287523
Immunohistochemistry Image
Flow Cytometry Image
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human, Mouse, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry, Proximity Ligation Assay
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, IF, ELISA pSer25
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, IF, ELISA pSer25 No Primary
Anti-TP53BP1 / 53BP1 Antibody (phospho-Ser25) LS-C291166
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human, Mouse, Rat
IHC, Immunofluorescence, ELISA
Unconjugated
TP53BP1 / 53BP1 Goat IgG Polyclonal Unconjugated Human IHC-P, IF, IP, PLA aa350-400
1
TP53BP1 / 53BP1 Goat IgG Polyclonal Unconjugated Human IHC-P, IF, IP, PLA aa350-400 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa350-400) LS-C290555
Immunohistochemistry Image
Goat Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human
IHC - Paraffin, Immunofluorescence, Immunoprecipitation, Proximity Ligation Assay
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse IHC-P, IF aa350-400
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse IHC-P, IF aa350-400 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa350-400) IHC-plus™ LS-B13416
Immunohistochemistry Image
Immunohistochemistry - Paraffin Image
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human, Mouse
IHC - Paraffin, Immunofluorescence
Unconjugated
TP53BP1 / 53BP1 Mouse IgG1 Monoclonal 6B3E10 Unconjugated Human IHC-P, WB, Flo, ELISA aa574-773
1
TP53BP1 / 53BP1 Mouse IgG1 Monoclonal 6B3E10 Unconjugated Human IHC-P, WB, Flo, ELISA aa574-773 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa574-773, clone 6B3E10) LS-C191834
Immunohistochemistry Image
Immunohistochemistry Image
Mouse Monoclonal [clone 6B3E10] (IgG1) to Human TP53BP1 / 53BP1
Human
IHC - Paraffin, Western blot, Flow Cytometry, ELISA
Unconjugated
TP53BP1 / 53BP1 Mouse IgG1 Monoclonal 6B3E10 Unconjugated Human IHC-P, WB, Flo, ELISA aa574-773
1
TP53BP1 / 53BP1 Mouse IgG1 Monoclonal 6B3E10 Unconjugated Human IHC-P, WB, Flo, ELISA aa574-773 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa574-773, clone 6B3E10) LS-C191833
Immunohistochemistry Image
Immunohistochemistry Image
Mouse Monoclonal [clone 6B3E10] (IgG1) to Human TP53BP1 / 53BP1
Human
IHC - Paraffin, Western blot, Flow Cytometry, ELISA
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Monkey IHC, ICC, IF, WB Internal
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Monkey IHC, ICC, IF, WB Internal No Primary
Anti-TP53BP1 / 53BP1 Antibody (Internal) LS-C124328
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human, Monkey
IHC, ICC, Immunofluorescence, Western blot
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Monkey ICC, IF, WB, Flo pSer1778
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Monkey ICC, IF, WB, Flo pSer1778 No Primary
Anti-TP53BP1 / 53BP1 Antibody (phospho-Ser1778) LS-C131179
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human, Monkey
ICC, Immunofluorescence, Western blot, Flow Cytometry
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, IF, WB, ELISA aa1-80
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, IF, WB, ELISA aa1-80 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa1-80) LS-C381819
Western blot Image
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human, Mouse, Rat
IHC, Immunofluorescence, Western blot, ELISA
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, IF, WB
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, IF, WB No Primary
Anti-TP53BP1 / 53BP1 Antibody LS-C334269
Immunohistochemistry Image
Immunohistochemistry Image
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human, Mouse, Rat
IHC, Immunofluorescence, Western blot
Unconjugated
TP53BP1 / 53BP1 Rabbit Polyclonal Unconjugated Human, Mouse IHC-P, ICC, IF, WB
1
TP53BP1 / 53BP1 Rabbit Polyclonal Unconjugated Human, Mouse IHC-P, ICC, IF, WB No Primary
Anti-TP53BP1 / 53BP1 Antibody LS-C91067
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human, Mouse
IHC - Paraffin, ICC, Immunofluorescence, Western blot
Unconjugated
TP53BP1 / 53BP1 Mouse IgG1 Monoclonal 6B3E10 Unconjugated Human IHC-P, WB, Flo aa500-800
1
TP53BP1 / 53BP1 Mouse IgG1 Monoclonal 6B3E10 Unconjugated Human IHC-P, WB, Flo aa500-800 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa500-800, clone 6B3E10) LS-C359362
Immunohistochemistry Image
Immunohistochemistry Image
Mouse Monoclonal [clone 6B3E10] (IgG1) to Human TP53BP1 / 53BP1
Human
IHC - Paraffin, Western blot, Flow Cytometry
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Monkey, Mouse, Bovine, Horse, Rabbit, Sheep IHC-P, ICC, WB aa1955-1972
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Monkey, Mouse, Bovine, Horse, Rabbit, Sheep IHC-P, ICC, WB aa1955-1972 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa1955-1972) LS-C313109
Immunohistochemistry Image
Immunohistochemistry Image
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human, Monkey, Mouse, Bovine, Horse, Rabbit, Sheep
IHC - Paraffin, ICC, Western blot
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, IF, ELISA pSer25
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, IF, ELISA pSer25 No Primary
Anti-TP53BP1 / 53BP1 Antibody (phospho-Ser25) LS-C381724
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human, Mouse, Rat
IHC, Immunofluorescence, ELISA
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, IF, WB
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, IF, WB No Primary
Anti-TP53BP1 / 53BP1 Antibody LS-C335073
Western blot Image
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human, Mouse, Rat
IHC, Immunofluorescence, Western blot
Unconjugated
TP53BP1 / 53BP1 Rabbit Polyclonal Unconjugated Human, Mouse, Rat IHC, IF, WB Asp2
1
TP53BP1 / 53BP1 Rabbit Polyclonal Unconjugated Human, Mouse, Rat IHC, IF, WB Asp2 No Primary
Anti-TP53BP1 / 53BP1 Antibody (Asp2) LS-C176577
Western blot Image
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human, Mouse, Rat
IHC, Immunofluorescence, Western blot
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, WB, ELISA pSer6
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, WB, ELISA pSer6 No Primary
Anti-TP53BP1 / 53BP1 Antibody (phospho-Ser6) LS-C291157
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human, Mouse, Rat
IHC, Western blot, ELISA
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, WB, ELISA pSer6
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, WB, ELISA pSer6 No Primary
Anti-TP53BP1 / 53BP1 Antibody (phospho-Ser6) LS-C291538
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human, Mouse, Rat
IHC, Western blot, ELISA
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Monkey, Mouse, Rat IHC, WB, ELISA pSer6
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Monkey, Mouse, Rat IHC, WB, ELISA pSer6 No Primary
Anti-TP53BP1 / 53BP1 Antibody (phospho-Ser6) LS-C381306
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human, Monkey, Mouse, Rat
IHC, Western blot, ELISA
Unconjugated
TP53BP1 / 53BP1 Rabbit Polyclonal Unconjugated,Biotin Conjugated,DY550 Conjugated,DY650 Conjugated,DY488 Conjugated Human, Mouse, Rat IHC-P, ICC, WB,IHC-P, ICC, WB,IHC-P, ICC, WB,IHC-P, ICC, WB,IHC-P, ICC, WB C-Terminus
5
TP53BP1 / 53BP1 Rabbit Polyclonal Unconjugated Human, Mouse, Rat IHC-P, ICC, WB C-Terminus No Primary
Anti-TP53BP1 / 53BP1 Antibody (C-Terminus) LS-C49071
Immunohistochemistry Image
Immunocytochemistry Image
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human, Mouse, Rat
IHC - Paraffin, ICC, Western blot
Unconjugated
TP53BP1 / 53BP1 Rabbit Polyclonal Biotin Conjugated Human, Mouse, Rat IHC-P, ICC, WB C-Terminus No Primary
Anti-TP53BP1 / 53BP1 Antibody (C-Terminus, Biotin) LS-C141098
Immunohistochemistry Image
Immunocytochemistry Image
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human, Mouse, Rat
IHC - Paraffin, ICC, Western blot
Biotin Conjugated
TP53BP1 / 53BP1 Rabbit Polyclonal DY550 Conjugated Human, Mouse IHC-P, ICC, WB C-Terminus No Primary
Anti-TP53BP1 / 53BP1 Antibody (C-Terminus, DY550) LS-C141102
Immunohistochemistry Image
Immunocytochemistry Image
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human, Mouse
IHC - Paraffin, ICC, Western blot
DY550 Conjugated
TP53BP1 / 53BP1 Rabbit Polyclonal DY650 Conjugated Human, Mouse IHC-P, ICC, WB C-Terminus No Primary
Anti-TP53BP1 / 53BP1 Antibody (C-Terminus, DY650) LS-C141099
Immunohistochemistry Image
Immunocytochemistry Image
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human, Mouse
IHC - Paraffin, ICC, Western blot
DY650 Conjugated
TP53BP1 / 53BP1 Rabbit Polyclonal DY488 Conjugated Human, Mouse IHC-P, ICC, WB C-Terminus No Primary
Anti-TP53BP1 / 53BP1 Antibody (C-Terminus, DY488) LS-C141100
Immunohistochemistry Image
Immunocytochemistry Image
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human, Mouse
IHC - Paraffin, ICC, Western blot
DY488 Conjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IF, WB, ELISA aa1-50
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IF, WB, ELISA aa1-50 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa1-50) LS-C117787
Immunofluorescence Image
Western blot Image
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human, Mouse, Rat
Immunofluorescence, Western blot, ELISA
Unconjugated
TP53BP1 / 53BP1 Mouse IgG1 Monoclonal Unconjugated,HRP Conjugated,Biotin Conjugated,FITC Conjugated,PE Conjugated,AP Conjugated,APC Conjugated Human ICC, WB, IP,ICC, WB, IP,ICC, WB, IP,ICC, WB, IP,ICC, WB, IP,ICC, WB, IP,ICC, WB, IP aa1-337
7
TP53BP1 / 53BP1 Mouse IgG1 Monoclonal Unconjugated Human ICC, WB, IP aa1-337 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa1-337) LS-C25829
Mouse Monoclonal (IgG1) to Human TP53BP1 / 53BP1
Human
ICC, Western blot, Immunoprecipitation
Unconjugated
TP53BP1 / 53BP1 Mouse IgG1 Monoclonal HRP Conjugated Human ICC, WB, IP No Primary
Anti-TP53BP1 / 53BP1 Antibody (HRP) LS-C548521
Mouse Monoclonal (IgG1) to Human TP53BP1 / 53BP1
Human
ICC, Western blot, Immunoprecipitation
HRP Conjugated
TP53BP1 / 53BP1 Mouse IgG1 Monoclonal Biotin Conjugated Human ICC, WB, IP No Primary
Anti-TP53BP1 / 53BP1 Antibody (Biotin) LS-C528426
Mouse Monoclonal (IgG1) to Human TP53BP1 / 53BP1
Human
ICC, Western blot, Immunoprecipitation
Biotin Conjugated
TP53BP1 / 53BP1 Mouse IgG1 Monoclonal FITC Conjugated Human ICC, WB, IP No Primary
Anti-TP53BP1 / 53BP1 Antibody (FITC) LS-C538381
Mouse Monoclonal (IgG1) to Human TP53BP1 / 53BP1
Human
ICC, Western blot, Immunoprecipitation
FITC Conjugated
TP53BP1 / 53BP1 Mouse IgG1 Monoclonal PE Conjugated Human ICC, WB, IP No Primary
Anti-TP53BP1 / 53BP1 Antibody (PE) LS-C656545
Mouse Monoclonal (IgG1) to Human TP53BP1 / 53BP1
Human
ICC, Western blot, Immunoprecipitation
PE Conjugated
TP53BP1 / 53BP1 Mouse IgG1 Monoclonal AP Conjugated Human ICC, WB, IP No Primary
Anti-TP53BP1 / 53BP1 Antibody (AP) LS-C510383
Mouse Monoclonal (IgG1) to Human TP53BP1 / 53BP1
Human
ICC, Western blot, Immunoprecipitation
AP Conjugated
TP53BP1 / 53BP1 Mouse IgG1 Monoclonal APC Conjugated Human ICC, WB, IP No Primary
Anti-TP53BP1 / 53BP1 Antibody (APC) LS-C518522
Mouse Monoclonal (IgG1) to Human TP53BP1 / 53BP1
Human
ICC, Western blot, Immunoprecipitation
APC Conjugated
TP53BP1 / 53BP1 Mouse IgG1 Monoclonal 2H6 Unconjugated Human IHC-P, WB aa1-300
1
TP53BP1 / 53BP1 Mouse IgG1 Monoclonal 2H6 Unconjugated Human IHC-P, WB aa1-300 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa1-300, clone 2H6) LS-C340168
Immunohistochemistry Image
Immunohistochemistry Image
Mouse Monoclonal [clone 2H6] (IgG1) to Human TP53BP1 / 53BP1
Human
IHC - Paraffin, Western blot
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human IHC, ELISA aa1720-1800
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human IHC, ELISA aa1720-1800 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa1720-1800) LS-C381820
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human
IHC, ELISA
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Biotin Conjugated Human ICC, WB, ELISA aa1724-1964
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Biotin Conjugated Human ICC, WB, ELISA aa1724-1964 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa1724-1964, Biotin) LS-C424370
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human
ICC, Western blot, ELISA
Biotin Conjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal FITC Conjugated Human ICC, WB, ELISA aa1724-1964
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal FITC Conjugated Human ICC, WB, ELISA aa1724-1964 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa1724-1964, FITC) LS-C424371
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human
ICC, Western blot, ELISA
FITC Conjugated
TP53BP1 / 53BP1 Rabbit Polyclonal Unconjugated Human, Mouse ICC, WB
1
TP53BP1 / 53BP1 Rabbit Polyclonal Unconjugated Human, Mouse ICC, WB No Primary
Anti-TP53BP1 / 53BP1 Antibody LS-C91068
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human, Mouse
ICC, Western blot
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse WB, ELISA aa10-90
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse WB, ELISA aa10-90 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa10-90) LS-C381822
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human, Mouse
Western blot, ELISA
Unconjugated
TP53BP1 / 53BP1 Rabbit Polyclonal Unconjugated Human, Mouse, Rat IHC-P, IF pSer25
1
TP53BP1 / 53BP1 Rabbit Polyclonal Unconjugated Human, Mouse, Rat IHC-P, IF pSer25 No Primary
Anti-TP53BP1 / 53BP1 Antibody (phospho-Ser25) LS-C357177
Immunohistochemistry Image
Immunofluorescence Image
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human, Mouse, Rat
IHC - Paraffin, Immunofluorescence
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit IHC-P, IF pSer25
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit IHC-P, IF pSer25 No Primary
Anti-TP53BP1 / 53BP1 Antibody (phospho-Ser25) LS-C286328
Immunohistochemistry Image
Immunohistochemistry Image
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human, Mouse, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit
IHC - Paraffin, Immunofluorescence
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse WB, ELISA aa14-63
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse WB, ELISA aa14-63 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa14-63) LS-C291242
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human, Mouse
Western blot, ELISA
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human WB, ELISA aa1724-1964
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human WB, ELISA aa1724-1964 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa1724-1964) LS-C373555
Western blot Image
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human
Western blot, ELISA
Unconjugated
TP53BP1 / 53BP1 Mouse IgM Monoclonal Unconjugated Human, Mouse WB, IP aa1-337
1
TP53BP1 / 53BP1 Mouse IgM Monoclonal Unconjugated Human, Mouse WB, IP aa1-337 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa1-337) LS-C25828
Mouse Monoclonal (IgM) to Human TP53BP1 / 53BP1
Human, Mouse
Western blot, Immunoprecipitation
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human IHC-P, ELISA aa1744-1793
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human IHC-P, ELISA aa1744-1793 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa1744-1793) LS-C118382
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human
IHC - Paraffin, ELISA
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Bovine, Dog, Horse, Rabbit WB, PLA C-Terminus
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Bovine, Dog, Horse, Rabbit WB, PLA C-Terminus No Primary
Anti-TP53BP1 / 53BP1 Antibody (C-Terminus) LS-C287176
Western blot Image
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human, Mouse, Bovine, Dog, Horse, Rabbit
Western blot, Proximity Ligation Assay
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human IHC-P, ELISA aa1758-1972
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human IHC-P, ELISA aa1758-1972 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa1758-1972) LS-C377316
Immunohistochemistry Image
Immunohistochemistry Image
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human
IHC - Paraffin, ELISA
Unconjugated
TP53BP1 / 53BP1 Rabbit Polyclonal Unconjugated Human IHC Asp2
1
TP53BP1 / 53BP1 Rabbit Polyclonal Unconjugated Human IHC Asp2 No Primary
Anti-TP53BP1 / 53BP1 Antibody (Asp2) LS-C191892
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human
IHC
Unconjugated
TP53BP1 / 53BP1 Mouse IgG1,k Monoclonal 1B9 Unconjugated Human ELISA
1
TP53BP1 / 53BP1 Mouse IgG1,k Monoclonal 1B9 Unconjugated Human ELISA No Primary
Anti-TP53BP1 / 53BP1 Antibody (clone 1B9) LS-C198358
Enzyme-Linked Immunosorbent Assay Image
Mouse Monoclonal [clone 1B9] (IgG1,k) to Human TP53BP1 / 53BP1
Human
ELISA
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Monkey WB Ser25/Ser29
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Monkey WB Ser25/Ser29 No Primary
Anti-TP53BP1 / 53BP1 Antibody (Ser25/Ser29) LS-C131177
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human, Monkey
Western blot
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Monkey WB
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human, Monkey WB No Primary
Anti-TP53BP1 / 53BP1 Antibody LS-C131178
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human, Monkey
Western blot
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human WB N-Terminus
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human WB N-Terminus No Primary
Anti-TP53BP1 / 53BP1 Antibody (N-Terminus) LS-C20110
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human
Western blot
Unconjugated
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human WB
1
TP53BP1 / 53BP1 Rabbit IgG Polyclonal Unconjugated Human WB No Primary
Anti-TP53BP1 / 53BP1 Antibody LS-C25916
Rabbit Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human
Western blot
Unconjugated
TP53BP1 / 53BP1 Rabbit Polyclonal Unconjugated Human, Mouse WB
1
TP53BP1 / 53BP1 Rabbit Polyclonal Unconjugated Human, Mouse WB No Primary
Anti-TP53BP1 / 53BP1 Antibody LS-C417270
Western blot Image
Rabbit Polyclonal to Human TP53BP1 / 53BP1
Human, Mouse
Western blot
Unconjugated
TP53BP1 / 53BP1 Goat IgG Polyclonal Unconjugated Human WB aa1614-1972
1
TP53BP1 / 53BP1 Goat IgG Polyclonal Unconjugated Human WB aa1614-1972 No Primary
Anti-TP53BP1 / 53BP1 Antibody (aa1614-1972) LS-C126099
Goat Polyclonal (IgG) to Human TP53BP1 / 53BP1
Human
Western blot
Unconjugated
Type Target Reactivity Sample Type
Cell-Based Phosphorylation TP53BP1 / 53BP1 Mouse, Human, Rat Adherent Cell Cultures
1
Mouse/Human/Rat Phospho-TP53BP1 / 53BP1 (Ser6) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1284
 Image
 Image
Cell-Based Phosphorylation ELISA
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
Cell-Based TP53BP1 / 53BP1 Mouse, Human, Rat Adherent Cell Cultures
1
Mouse/Human/Rat TP53BP1 / 53BP1 ELISA Kit (Cell-Based ELISA) - LS-F1771
 Image
 Image
Cell-Based ELISA
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
Sandwich TP53BP1 / 53BP1 Human Tissue Homogenates
1
Human TP53BP1 / 53BP1 ELISA Kit (Sandwich ELISA) - LS-F9012
 Image
 Image
Sandwich ELISA
96-Well Strip Plate
Human
0.313-20 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
Type Target Tag Species Source Purified Biological Activity Known Endotoxin Level Animal-Free
Recombinant TP53BP1 / 53BP1 His + S Human E. coli
1
Human TP53BP1 / 53BP1 Protein (Recombinant His + S) - LS-G25829
E. coli Expression System
His + S
Lyophilized
30.8 kDa

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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