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TP / Thymidine Phosphorylase

thymidine phosphorylase

TP / Thymidine Phosphorylase is an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified.

Gene Name:	thymidine phosphorylase
Synonyms:	TYMP, ECGF1, HPD-ECGF, MEDPS1, MNGIE, MTDPS1, PD-ECGF, Thymidine phosphorylase, PDECGF, ECGF, Gliostatin, TdRPase, TP
Target Sequences:	NM_001953 NP_001944.1 P19971

Publications (1)

Expression of thymidine phosphorylase in lymph nodes involved with mycosis fungoides and szary syndrome. Nie X, Bhat R, Al-Saleem ED, Vonderheid EC, Hou JS. Advances in hematology. 2011 2011:875135. [PubMed:22162690] [PMC:PMC3226296]

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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