Toxoplasma gondii

Toxoplasma gondii is an obligate, intracellular, parasitic protozoan that causes the toxoplasmosis. T. gondii is capable of infecting virtually all warm-blooded animals, although felids such as domestic cats are the only known hosts in which the parasite can undergo sexual reproduction. There are three stages of infection: the tachyzoite stage of rapid division, the bradyzoite stage of slow division within tissue cysts, and the oocyst environmental stage. When an oocyst or tissue cyst is ingested by a human, the resilient cyst wall is dissolved by proteolytic enzymes in the stomach and small intestine, freeing sporozoites from within the oocyst. The parasites first invade cells in and surrounding the intestinal epithelium, and inside these cells, the parasites differentiate into tachyzoites, the motile and quickly multiplying cellular stage of T. gondii. Tissue cysts in tissues such as brain and muscle tissue form approximately 7–10 days after initial infection.

Toxoplasma gondii Target Details

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