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TOR2A
Torsin family 2, member A
TOR2A is a member of the AAA family of adenosine triphosphatases with similarity to Clp proteases and heat shock proteins. Alternative splicing at this locus results in the translation of multiple isoforms of the encoded protein, some of which contain salusin peptides in the C-terminal region. These peptides may play roles in hypotension, myocardial growth and the induction of mitogenesis, and may also be involved in the pathogenesis of atherosclerosis. The antimicrobial peptide salusin-beta has antibacterial activity.
| Gene Name: | Torsin family 2, member A |
| Synonyms: | TOR2A, Prosalusin, Torsin-related protein 1, Torsin family 2, member A, TORP1, Torsin family 2 member A, Torsin-2A |
| Target Sequences: | NM_001085347 NP_001078816.1 Q5JU69 |
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