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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TOR1A / Torsin A

torsin family 1, member A (torsin A)

Protein with chaperone functions important for the control of protein folding, processing, stability and localization as well as for the reduction of misfolded protein aggregates. Involved in the regulation of synaptic vesicle recycling, controls STON2 protein stability in collaboration with the COP9 signalosome complex (CSN). In the nucleus, may link the cytoskeleton with the nuclear envelope, this mechanism seems to be crucial for the control of nuclear polarity, cell movement and, specifically in neurons, nuclear envelope integrity. Participates in the cellular trafficking and may regulate the subcellular location of multipass membrane proteins such as the dopamine transporter SLC6A3, leading to the modulation of dopamine neurotransmission. In the endoplasmic reticulum, plays a role in the quality control of protein folding by increasing clearance of misfolded proteins such as SGCE variants or holding them in an intermediate state for proper refolding. May have a redundant function with TOR1B in non-neural tissues.

Gene Name: torsin family 1, member A (torsin A)
Synonyms: TOR1A, DYT1, Torsin A, DQ2, Dystonia 1 protein, Torsin family 1 member A, Torsin-1A
Target Sequences: NM_000113 NP_000104.1 O14656

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Products
Antibodies (41)
Primary (41)
TOR1A / Torsin A (41)
Human (33)
Mouse (18)
Rat (5)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Monkey (4)
Pig (4)
Rabbit (4)
IHC (6)
IHC-P (1)
WB (37)
ELISA (13)
ICC (1)
IF (1)
IP (1)
rabbit (38)
mouse (3)
IgG (16)
IgG1 (2)
monoclonal mc (2)
polyclonal pc (39)
AP Conjugated (1)
APC (2)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (5)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (3)
Unconjugated (15)
aa267-295 (8)
aa33-321 (8)
aa41-333 (8)
aa201-250 (4)
No (41)
TOR1A / Torsin A Antibody - Immunohistochemistry of paraffin-embedded human colon cancer using TOR1A Antibody at dilution of 1:100
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TOR1A / Torsin A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$285; 100 µg/$385
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TOR1A / Torsin A Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
ICC, IP, WB
Unconjugated
100 µl/$695
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TOR1A / Torsin A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$435
TOR1A / Torsin A Antibody - 1:100 staining mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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TOR1A / Torsin A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µl/$325; 200 µl/$375
TOR1A / Torsin A Antibody - Immunohistochemical analysis of TorsinA staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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TOR1A / Torsin A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$255; 100 µl/$295; 200 µl/$375
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TOR1A / Torsin A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$235; 120 µl/$295; 200 µl/$395
TOR1A / Torsin A Antibody - Western blot of extracts of MCF-7 cell lines, using TOR1A antibody.
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TOR1A / Torsin A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µl/$385
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TOR1A / Torsin A Rabbit anti-Human Polyclonal (aa267-295) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$590
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TOR1A / Torsin A Rabbit anti-Human Polyclonal (aa267-295) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$740
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TOR1A / Torsin A Rabbit anti-Human Polyclonal (aa267-295) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$740
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TOR1A / Torsin A Rabbit anti-Human Polyclonal (aa267-295) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$740
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TOR1A / Torsin A Rabbit anti-Human Polyclonal (aa267-295) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$740
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TOR1A / Torsin A Rabbit anti-Human Polyclonal (aa267-295) (AP) Antibody
Human
ELISA, WB
AP Conjugated
200 µl/$740
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TOR1A / Torsin A Rabbit anti-Human Polyclonal (aa267-295) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$740
TOR1A / Torsin A Antibody - Western blot of TOR1A / Torsin A antibody.
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TOR1A / Torsin A Rabbit anti-Mouse Polyclonal (aa41-333) Antibody
Mouse
WB
Unconjugated
100 µl/$265; 200 µl/$305; 500 µl/$445; 1 ml/$545
TOR1A / Torsin A Antibody - Western blot of TOR1A / Torsin A antibody.
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TOR1A / Torsin A Rabbit anti-Mouse Polyclonal (aa41-333) (FITC) Antibody
Mouse
WB
FITC Conjugated
200 µl/$365; 500 µl/$605; 1 ml/$755
TOR1A / Torsin A Antibody - Western blot of TOR1A / Torsin A antibody.
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TOR1A / Torsin A Rabbit anti-Mouse Polyclonal (aa41-333) (APC) Antibody
Mouse
WB
APC Conjugated
200 µl/$445; 500 µl/$860; 1 ml/$1,080
TOR1A / Torsin A Antibody - Western blot of TOR1A / Torsin A antibody.
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TOR1A / Torsin A Rabbit anti-Mouse Polyclonal (aa41-333) (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
1 ml/$1,620
TOR1A / Torsin A Antibody - Western blot of TOR1A / Torsin A antibody.
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TOR1A / Torsin A Rabbit anti-Mouse Polyclonal (aa41-333) (PE) Antibody
Mouse
WB
PE Conjugated
200 µl/$445; 500 µl/$860; 1 ml/$1,080
TOR1A / Torsin A Antibody - Western blot of TOR1A / Torsin A antibody.
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TOR1A / Torsin A Rabbit anti-Mouse Polyclonal (aa41-333) (Cy3) Antibody
Mouse
WB
Cy3 Conjugated
200 µl/$445; 500 µl/$860; 1 ml/$1,080
TOR1A / Torsin A Antibody - DYT1 Antibody western blot of ZR-75-1 cell line lysates (35 ug/lane). The DYT1 antibody detected the DYT1 protein (arrow).
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TOR1A / Torsin A Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
0.1 ml/$325
TOR1A / Torsin A Antibody - TOR1A / Torsin A antibody Western blot of Fetal Brain lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TOR1A / Torsin A Rabbit anti-Human Polyclonal (aa201-250) Antibody
Rabbit, Mouse, Dog, Pig, Human, Monkey
WB
Unconjugated
100 µl/$365
TOR1A / Torsin A Antibody - TOR1A Antibody western blot of MCF-7 cell line lysates (35 ug/lane). The TOR1A antibody detected the TOR1A protein (arrow).
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TOR1A / Torsin A Rabbit anti-Human Polyclonal (aa267-295) Antibody
Human
WB
Unconjugated
400 µl/$325
TOR1A / Torsin A Antibody - Western blot analysis of extracts of various cell lines, using TOR1A antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 15s.
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TOR1A / Torsin A Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$215; 50 µl/$235; 100 µl/$295; 200 µl/$385
TOR1A / Torsin A Antibody - Western blot of TOR1A / Torsin A antibody.
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TOR1A / Torsin A Rabbit anti-Human Polyclonal (aa33-321) Antibody
Human
WB
Unconjugated
100 µl/$255; 200 µl/$305; 500 µl/$445; 1 ml/$530
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).