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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TOR1A / Torsin A

torsin family 1, member A (torsin A)

Protein with chaperone functions important for the control of protein folding, processing, stability and localization as well as for the reduction of misfolded protein aggregates. Involved in the regulation of synaptic vesicle recycling, controls STON2 protein stability in collaboration with the COP9 signalosome complex (CSN). In the nucleus, may link the cytoskeleton with the nuclear envelope, this mechanism seems to be crucial for the control of nuclear polarity, cell movement and, specifically in neurons, nuclear envelope integrity. Participates in the cellular trafficking and may regulate the subcellular location of multipass membrane proteins such as the dopamine transporter SLC6A3, leading to the modulation of dopamine neurotransmission. In the endoplasmic reticulum, plays a role in the quality control of protein folding by increasing clearance of misfolded proteins such as SGCE variants or holding them in an intermediate state for proper refolding. May have a redundant function with TOR1B in non-neural tissues.

Gene Name: torsin family 1, member A (torsin A)
Synonyms: TOR1A, DYT1, Torsin A, DQ2, Dystonia 1 protein, Torsin family 1 member A, Torsin-1A
Target Sequences: NM_000113 NP_000104.1 O14656

Filtered by: None
Target
TOR1A / Torsin A (42)
Reactivity
Human (33)
Mouse (18)
Rat (5)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Monkey (4)
Pig (4)
Rabbit (4)
Application
IHC (7)
IHC-P (2)
WB (38)
ELISA (13)
ICC (1)
IF (1)
IP (1)
Host
rabbit (39)
mouse (3)
Isotype
IgG (17)
IgG1 (2)
Clonality
monoclonal mc (2)
polyclonal pc (40)
Format
AP Conjugated (1)
APC (2)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (5)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (3)
Unconjugated (16)
Epitope
aa267-295 (8)
aa33-321 (8)
aa41-333 (8)
aa201-250 (4)
Publications
No (42)
Showing 1-25 of 42 results

IHC-plus™ TOR1A / Torsin A Antibody LS-B14131
Rabbit Polyclonal (IgG) to Human TOR1A / Torsin A
IHC, IHC-P, WB
Unconjugated
40µg 80µl 0.5mg/ml  $425.00
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)

TOR1A / Torsin A Antibody LS-C39761
Mouse Monoclonal (IgG1) to Human TOR1A / Torsin A
Mouse, Rat, Human
ICC, IP, WB
Unconjugated
100µl  $695.00

TOR1A / Torsin A Antibody LS-C499959
Rabbit Polyclonal (IgG) to Human TOR1A / Torsin A
Human
ELISA, IF, IHC
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human colon cancer using TOR1A Antibody at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using TOR1A Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

TOR1A / Torsin A Antibody LS-C661180
Rabbit Polyclonal (IgG) to Human TOR1A / Torsin A
Human
ELISA, IHC, WB
Unconjugated
100µg  $435.00

TOR1A / Torsin A Antibody LS-C806335
Rabbit Polyclonal (IgG) to Human TOR1A / Torsin A
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Western blot Image

TOR1A / Torsin A Antibody LS-C482347
Rabbit Polyclonal to Human TOR1A / Torsin A
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50µl 1mg/ml  $255.00; 100µl 1mg/ml  $295.00; 200µl 1mg/ml  $375.00
Immunohistochemical analysis of TorsinA staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Western blot analysis of TorsinA expression in MCF7 (A); SW480 (B); mouse liver (C) whole cell lysates.

TOR1A / Torsin A Antibody LS-C772884
Rabbit Polyclonal (IgG) to Human TOR1A / Torsin A
Mouse, Rat, Human
IHC, WB
Unconjugated
60µl 1mg/ml  $235.00; 120µl 1mg/ml  $295.00; 200µl 1mg/ml  $395.00

TOR1A / Torsin A Antibody LS-C192759
Rabbit Polyclonal to Human TOR1A / Torsin A
Mouse, Rat, Human
IHC, WB
Unconjugated
100µl  $385.00
Western blot of extracts of MCF-7 cell lines, using TOR1A antibody.

TOR1A / Torsin A Antibody (aa267-295) LS-C325869
Rabbit Polyclonal (IgG) to Human TOR1A / Torsin A
Human
ELISA, WB
Unconjugated
200µl  $590.00

TOR1A / Torsin A Antibody (aa267-295, Biotin) LS-C271972
Rabbit Polyclonal (IgG) to Human TOR1A / Torsin A
Human
ELISA, WB
Biotin Conjugated
200µl  $740.00

TOR1A / Torsin A Antibody (aa267-295, FITC) LS-C271973
Rabbit Polyclonal (IgG) to Human TOR1A / Torsin A
Human
ELISA, WB
FITC Conjugated
200µl  $740.00

TOR1A / Torsin A Antibody (aa267-295, AP) LS-C271970
Rabbit Polyclonal (IgG) to Human TOR1A / Torsin A
Human
ELISA, WB
AP Conjugated
200µl  $740.00

TOR1A / Torsin A Antibody (aa267-295, Azide-free, HRP) LS-C271974
Rabbit Polyclonal (IgG) to Human TOR1A / Torsin A
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl  $740.00

TOR1A / Torsin A Antibody (aa267-295, PE) LS-C271975
Rabbit Polyclonal (IgG) to Human TOR1A / Torsin A
Human
ELISA, WB
PE Conjugated
200µl  $740.00

TOR1A / Torsin A Antibody (aa267-295, APC) LS-C271971
Rabbit Polyclonal (IgG) to Human TOR1A / Torsin A
Human
ELISA, WB
APC Conjugated
200µl  $740.00

TOR1A / Torsin A Antibody (aa41-333) LS-C374887
Rabbit Polyclonal to Mouse TOR1A / Torsin A
Mouse
WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $265.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $545.00
Western blot of TOR1A / Torsin A antibody.

TOR1A / Torsin A Antibody (aa41-333, HRP) LS-C713690
Rabbit Polyclonal to Mouse TOR1A / Torsin A
Mouse
WB
HRP Conjugated
100µl 0.5mg/ml  $295.00; 200µl 0.5mg/ml  $345.00; 1ml 0.5mg/ml  $695.00
Western blot of TOR1A / Torsin A antibody.

TOR1A / Torsin A Antibody (aa41-333, Biotin) LS-C688802
Rabbit Polyclonal to Mouse TOR1A / Torsin A
Mouse
WB
Biotin Conjugated
100µl 0.5mg/ml  $275.00; 200µl 0.5mg/ml  $315.00; 1ml 0.5mg/ml  $590.00
Western blot of TOR1A / Torsin A antibody.

TOR1A / Torsin A Antibody (aa41-333, FITC) LS-C695825
Rabbit Polyclonal to Mouse TOR1A / Torsin A
Mouse
WB
FITC Conjugated
100µl 0.5mg/ml  $285.00; 200µl 0.5mg/ml  $335.00; 1ml 0.5mg/ml  $650.00
Western blot of TOR1A / Torsin A antibody.

TOR1A / Torsin A Antibody (aa41-333, APC) LS-C718910
Rabbit Polyclonal to Mouse TOR1A / Torsin A
Mouse
WB
APC Conjugated
100µl 0.1mg/ml  $275.00; 200µl 0.1mg/ml  $325.00; 1ml 0.1mg/ml  $605.00
Western blot of TOR1A / Torsin A antibody.

TOR1A / Torsin A Antibody LS-C159501
Mouse Monoclonal (IgG1) to Human TOR1A / Torsin A
Human
WB
Unconjugated
0.1ml  $325.00
DYT1 Antibody western blot of ZR-75-1 cell line lysates (35 ug/lane). The DYT1 antibody detected the DYT1 protein (arrow).

TOR1A / Torsin A Antibody (aa201-250) LS-C146485
Rabbit Polyclonal to Human TOR1A / Torsin A
Rabbit, Mouse, Dog, Pig, Human, Monkey
WB
Unconjugated
100µl 0.5mg/ml  $365.00
TOR1A / Torsin A antibody Western blot of Fetal Brain lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TOR1A / Torsin A Antibody LS-C750025
Rabbit Polyclonal (IgG) to Human TOR1A / Torsin A
Mouse, Human
WB
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00
Western blot analysis of extracts of various cell lines, using TOR1A antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 15s.

TOR1A / Torsin A Antibody (aa267-295) LS-C157243
Rabbit Polyclonal to Human TOR1A / Torsin A
Human
WB
Unconjugated
400µl  $325.00
TOR1A Antibody western blot of MCF-7 cell line lysates (35 ug/lane). The TOR1A antibody detected the TOR1A protein (arrow).

TOR1A / Torsin A Antibody (aa33-321) LS-C374892
Rabbit Polyclonal to Human TOR1A / Torsin A
Human
WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $530.00
Western blot of TOR1A / Torsin A antibody.
Western Blot; Sample: Recombinant TOR1A, Human.
Showing 1-25 of 42 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).