LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us

TOPORS

topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase

Functions as an E3 ubiquitin-protein ligase and as an E3 SUMO1-protein ligase. Probable tumor suppressor involved in cell growth, cell proliferation and apoptosis that regulates p53/TP53 stability through ubiquitin-dependent degradation. May regulate chromatin modification through sumoylation of several chromatin modification-associated proteins. May be involved in DNA damage-induced cell death through IKBKE sumoylation.

Gene Name: topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
Synonyms: TOPORS, p53-binding protein 3, LUN, SUMO1-protein E3 ligase Topors, TP53BPL, RP31, p53BP3
Target Sequences: NM_005802 NP_005793.2 Q9NS56

Filtered By: None
Target
TOPORS (3)
Reactivity
Human (3)
Application
IHC (3)
IHC-P (3)
WB (2)
ELISA (1)
IF (3)
IP (1)
Host
rabbit (2)
mouse (1)
Isotype
IgG (2)
IgG2a,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (2)
Clone
5G11 (1)
Format
Unconjugated (3)
Epitope
aa995-1045 (2)
Publications
No (3)
Showing 1-3 of 3 results

TOPORS Antibody (clone 5G11) IHC-plus™ LS-B4493
Mouse Monoclonal [clone 5G11] (IgG2a,k) to Human TOPORS
Human
ELISA IF IHC IHC-P WB
Unconjugated
50µg 0.4mg/ml  $485.00
Anti-TOPORS antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Immunofluorescence of monoclonal antibody to TOPORS on HeLa cell (antibody concentration 10 ug/ml).
Anti-TOPORS antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Immunofluorescence of monoclonal antibody to TOPORS on HeLa cell (antibody concentration 10 ug/ml).

TOPORS Antibody (aa995-1045) LS-C288932
Rabbit Polyclonal (IgG) to Human TOPORS
Human
IF IHC IHC-P IP WB
Unconjugated
100µl 0.2mg/ml  $395.00
Detection of Human TOPORS by Immunohistochemistry. Sample: FFPE section of human testicular seminoma. Antibody: Affinity purified rabbit anti-TOPORS used at a dilution of 1:200 (1 ug/ml). Detection: DAB.
Detection of Human TOPORS by Immunohistochemistry. Sample: FFPE section of human testicular seminoma. Antibody: Affinity purified rabbit anti-TOPORS used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

TOPORS Antibody (aa995-1045) LS-C286834
Rabbit Polyclonal (IgG) to Human TOPORS
Human
IF IHC IHC-P
Unconjugated
100µl  $415.00
Detection of Human TOPORS by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-TOPORS used at a dilution of 1:250.
Detection of Human TOPORS by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-TOPORS used at a dilution of 1:100. Detection: Red-fluorescent Goat anti-Rabbit IgG-heavy and light chain cross-adsorbed Antibody DyLight 594 Conjugated (A120-601D4) used at a dilution of 1:100.
Detection of Human TOPORS by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-TOPORS used at a dilution of 1:250.
Detection of Human TOPORS by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-TOPORS used at a dilution of 1:100. Detection: Red-fluorescent Goat anti-Rabbit IgG-heavy and light chain cross-adsorbed Antibody DyLight 594 Conjugated (A120-601D4) used at a dilution of 1:100.
Showing 1-3 of 3 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

Get Social With Us!
Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy