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TNR / Tenascin R

tenascin R

Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrix components. These interactions can influence cellular behavior by either evoking a stable adhesion and differentiation, or repulsion and inhibition of neurite growth. Binding to cell surface gangliosides inhibits RGD-dependent integrin-mediated cell adhesion and results in an inhibition of PTK2/FAK1 (FAK) phosphorylation and cell detachment. Binding to membrane surface sulfatides results in a oligodendrocyte adhesion and differentiation. Interaction with CNTN1 induces a repulsion of neurons and an inhibition of neurite outgrowth. Interacts with SCN2B may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier. TNR-linked chondroitin sulfate glycosaminoglycans are involved in the interaction with FN1 and mediate inhibition of cell adhesion and neurite outgrowth. The highly regulated addition of sulfated carbohydrate structure may modulate the adhesive properties of TNR over the course of development and during synapse maintenance.

Gene Name: tenascin R
Family/Subfamily: Fibronectin , not assigned-Fibronectin
Synonyms: TNR, Janusin, Tenascin-R, TN-R, Restrictin, Tenascin R
Target Sequences: NM_003285 NP_003276.3 Q92752

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Products
ELISA Kits (14)
Custom (4)
Sandwich (10)
TNR / Tenascin R (14)
Human (6)
Mouse (1)
Rat (1)
Chicken (2)
Guinea pig (1)
Monkey (1)
Porcine (1)
Rabbit (1)
96-Well Microplate (2)
96-Well Strip Plate (11)
No (14)
Cell Culture Supernatants (3)
Cell Lysates (1)
EDTA Plasma (1)
Heparin Plasma (1)
Plasma (4)
Serum (5)
Tissue Homogenates (1)
TNR / Tenascin R ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
TNR / Tenascin R ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
TNR / Tenascin R ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
TNR / Tenascin R ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
TNR / Tenascin R ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
TNR / Tenascin R ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
TNR / Tenascin R ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
TNR / Tenascin R ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$783
TNR / Tenascin R ELISA Kit
Select
Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$929
TNR / Tenascin R ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
TNR / Tenascin R ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
TNR / Tenascin R ELISA Kit
Select
Sandwich
Human
156 - 10000 pg/ml
Cell Culture Supernatants, EDTA Plasma, Heparin Plasma, Serum
1 Plate/$795
TNR / Tenascin R ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.2 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$672
TNR / Tenascin R ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$564
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).