TNNI1

troponin I type 1 (skeletal, slow)

Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.

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Products

Proteins (11)

Type

Over-Expression Lysate (2)

Recombinant (9)

Target

TNNI1 (11)

Publications

No (11)

Tag

10His-DDK(Flag), N-terminus + Myc, C-terminus (1)

6His, N-terminus (1)

DDK,C-terminus (1)

GST (1)

His (3)

His, N-Terminal (1)

Myc-DDK (Flag) (3)

Species

Human (7)

Mouse (2)

Rat (1)

Source

293T Cells (1)

E. coli (6)

HEK 293 Cells (2)

Sf9 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (3)

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Human TNNI1 Protein (Recombinant His) (aa1-103) - LS-G15216

Source:

E. coli

Tag:

His

Molecular Weight:

23.2 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Mouse TNNI1 Protein (Recombinant 6His, N-terminus) (aa1-187) - LS-G15218

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

23.2 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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Human TNNI1 Protein (Recombinant His) - LS-G2011

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human TNNI1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67206

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.5 kDa

Price:

20 µg/$1,107

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Rat TNNI1 Protein (Recombinant His) (aa1-187) - LS-G15217

Source:

E. coli

Tag:

His

Molecular Weight:

23.2 kDa

Price:

10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900

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Human TNNI1 Protein (Recombinant GST) (Full Length) - LS-G30740

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

46.31 kDa

Price:

10 µg/$479; 25 µg/$670

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TNNI1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100017

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.5 kDa

Price:

100 µg/$494

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Mouse TNNI1 Protein (Recombinant 10His-DDK(Flag), N-terminus + Myc, C-terminus) (Full Length) - LS-G136549

Source:

E. coli

Tag:

10His-DDK(Flag), N-terminus + Myc, C-terminus

Molecular Weight:

29.6 kDa

Price:

20 µg/$405; 1 mg/$1,679; 100 µg/$598

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Human TNNI1 Protein (Recombinant His, N-Terminal) - LS-G144959

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

21.5 kDa

Price:

50 µg/$419

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Human TNNI1 Protein (Recombinant DDK,C-terminus) - LS-G142431

Source:

Sf9 Cells

Tag:

DDK,C-terminus

Molecular Weight:

21.5 kDa

Price:

20 µg/$677

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Human TNNI1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79334

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.5 kDa

Price:

20 µg/$150

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