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TNIP3

TNFAIP3 interacting protein 3

Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.

Gene Name: TNFAIP3 interacting protein 3
Synonyms: TNIP3, ABIN-3, ABIN-3 beta, ABIN3, Listeria induced, LIND, Listeria-induced gene protein, TNIP3 beta, TNFAIP3 interacting protein 3, TNFAIP3-interacting protein 3
Target Sequences: NM_024873 NP_079149.3 Q96KP6

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).