TNFSF9 / CD137L

tumor necrosis factor (ligand) superfamily, member 9

TNFSF9 / CD137L is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.

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Products

Proteins (21)

Type

Over-Expression Lysate (2)

Recombinant (19)

Target

TNFSF9 / CD137L (21)

Publications

No (21)

Tag

10His, N-terminus (2)

6His, C-terminus (2)

DDK (Flag) (1)

DDK,N-terminus (1)

Fc, C-terminus (1)

Fc, N-terminus (1)

GST, N-terminus (1)

His (3)

His, N-Terminal (1)

His-AVI, N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (3)

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Species

Human (16)

Mouse (4)

Source

293T Cells (1)

E. coli (11)

HEK 293 Cells (5)

Human Cells (2)

Mammalian Cells (1)

Wheat Germ Extract (1)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (10)

Biologically Active

Biologically active (3)

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Human TNFSF9 / CD137L Protein (Recombinant GST, N-terminus) (aa145-254) - LS-G60848

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human TNFSF9 / CD137L Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64743

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.4 kDa

Price:

20 µg/$1,107

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Human TNFSF9 / CD137L Protein (Recombinant Fc, N-terminus) (Arg71-Glu254) - LS-G40343

Source:

Human Cells

Tag:

Fc, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

46.1kD

Price:

50 µg/$395; 500 µg/$1,585; 1 mg/$2,157

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Mouse TNFSF9 / CD137L Protein (Recombinant 10His, N-terminus) (Arg104-Glu309) - LS-G40358

Source:

Human Cells

Tag:

10His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

25.6kD

Price:

10 µg/$288; 50 µg/$442; 500 µg/$1,377; 1 mg/$1,765

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Human TNFSF9 / CD137L Protein (Recombinant His, N-Terminal) (Ala50-Glu254) - LS-G96738

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

24 kDa

Price:

10 µg/$265; 100 µg/$365; 250 µg/$518; 50 µg/$315

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Human TNFSF9 / CD137L Protein (Recombinant His) (aa52-254) - LS-G22394

Source:

E. coli

Tag:

His

Molecular Weight:

25.4 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human TNFSF9 / CD137L Protein (Recombinant His) (aa42-253) - LS-G25392

Source:

E. coli

Tag:

His

Molecular Weight:

25.8 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Mouse TNFSF9 / CD137L Protein (Recombinant His-T7) (aa105-309) - LS-G25393

Source:

E. coli

Tag:

His-T7

Molecular Weight:

26.6 kDa

Price:

10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225

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Human TNFSF9 / CD137L Protein (Recombinant 6His, C-terminus) (Arg71-Glu254) - LS-G39787

Source:

E. coli

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

20.6kD

Price:

10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157

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Mouse TNFSF9 / CD137L Protein (Recombinant 10His, N-terminus) (Arg104-Glu309) - LS-G139873

Source:

Mammalian Cells

Tag:

10His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

25.6 kDa

Price:

10 µg/$288; 50 µg/$436

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Human TNFSF9 / CD137L Protein (Recombinant DDK,N-terminus) - LS-G134351

Source:

HEK 293 Cells

Tag:

DDK,N-terminus

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Molecular Weight:

~23 kDa (SDS-PAGE)

Price:

50 µg/$470

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Human TNFSF9 / CD137L Protein (Recombinant His-AVI, N-terminus) - LS-G146217

Source:

E. coli

Tag:

His-AVI, N-terminus

Biological Activity:

Biologically active

Molecular Weight:

24.3kDa

Price:

50 µg/$421; 100 µg/$590

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Human TNFSF9 / CD137L Protein (Recombinant 6His, C-terminus) (Arg71-Glu254) - LS-G139500

Source:

E. coli

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

41.8 kDa

Price:

20 µg/$360; 100 µg/$728

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Human TNFSF9 / CD137L Protein (Recombinant Fc, C-terminus) - LS-G142287

Source:

HEK 293 Cells

Tag:

Fc, C-terminus

Molecular Weight:

46 kDa

Price:

20 µg/$1,107

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Human TNFSF9 / CD137L Protein (Recombinant) - LS-G131421

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

~19.6 kDa

Price:

20 µg/$395; 1 mg/$4,915

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Mouse TNFSF9 / CD137L Protein (Recombinant DDK (Flag)) (aa104-309) - LS-G3730

Source:

HEK 293 Cells

Tag:

DDK (Flag)

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

~40kDa (SDS-PAGE)

Price:

50 µg/$456

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Human TNFSF9 / CD137L Protein (Recombinant) (aa71-254) - LS-G5740

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

19.4 kDa

Price:

5 µg/$282; 500 µg/$1,747; 100 µg/$957

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Human TNFSF9 / CD137L Protein (Recombinant) - LS-G337

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

19.5 kDa

Price:

5 µg/$268; 20 µg/$349

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Human TNFSF9 / CD137L Protein (Recombinant His) - LS-G529

Source:

E. coli

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human TNFSF9 / CD137L Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74049

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.4 kDa

Price:

20 µg/$150

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TNFSF9 / CD137L Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117069

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.4 kDa

Price:

100 µg/$494

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