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TNFSF4 / OX40L / CD252
tumor necrosis factor (ligand) superfamily, member 4
TNFSF4 / OX40L is a cytokine of the tumor necrosis factor (TNF) ligand family. The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells. Polymorphisms in this gene have been associated with Sjogren's syndrome and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.
| Gene Name: | tumor necrosis factor (ligand) superfamily, member 4 |
| Family/Subfamily: | TNF , not assigned-TNF |
| Synonyms: | TNFSF4, CD134 ligand, CD134L, CD252 antigen, Glycoprotein Gp34, OX-40L, OX40 ligand, TXGP1, OX40L, OX4OL, CD252, gp34, OX40 antigen ligand |
| Target Sequences: | NM_003326 NP_003317.1 P23510 |
Publications (3)
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