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TNFRSF9 / 4-1BB / CD137

tumor necrosis factor receptor superfamily, member 9

TNFRSF9 / 4-1BB / CD137 is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.

Gene Name: tumor necrosis factor receptor superfamily, member 9
Family/Subfamily: TNF Receptor , not assigned-TNF Receptor
Synonyms: TNFRSF9, 4-1BB ligand receptor, 4-1BB, CD137 antigen, CD137, Homolog of mouse 4-1BB, ILA, Receptor protein 4-1BB, T cell antigen ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CDw137
Target Sequences: NM_001561 NP_001552.2 Q07011

Publications (2)

1
Progression of benign prostatic hyperplasia is associated with pro-inflammatory mediators and chronic activation of prostate-infiltrating lymphocytes. Norström MM, Rådestad E, Sundberg B, Mattsson J, Henningsohn L, Levitsky V, Uhlin M. Oncotarget. 2016 7:23581-93. (Flo, ELISA; Human) [Full Text Article] [PubMed:26993768] [PMC:PMC5029649]
2
CD137 (4-1BB) Engagement Fine-Tunes Synergistic IL-15- and IL-21-Driven NK Cell Proliferation. Laurent Vidard, Christine Dureuil, Jérémy Baudhuin, Lionel Vescovi, Laurence Durand, Véronique Sierra, Eric Parmantier. Journal of immunology (Baltimore, Md. : 1950). 2019 August;203:676-685. [Full Text Article] [PubMed:31201235]

☰ Filters
Products
Proteins (33)
Recombinant (33)
TNFRSF9 / 4-1BB / CD137 (33)
No (33)
6His, C-terminus (4)
DDK (Flag)-His, C-terminus (1)
Fc (1)
Fc, C-terminus (6)
Fc/6His,C-terminus (1)
Fc-6His, C-terminus (2)
GST (1)
GST, N-terminus (2)
His (3)
His, N-Terminal (1)
His,C-terminus (1)
Human IgG1 Fc (3)
Human IgG1 Fc, C-terminus (1)
mFc, C-terminus (1)
Mouse IgG2a Fc, N-terminus (1)
Crab-eating macaque (2)
Cynomolgus (1)
Human (26)
Mouse (4)
CHO Cells (2)
E. coli (8)
HEK 293 Cells (4)
Human Cells (5)
Mammalian Cells (11)
Wheat Germ Extract (3)
Purified (11)
Low endotoxin level (25)
Biologically active (10)
Select
Mammalian Cells
6His, C-terminus
Less than 0.1 ng/mL (Less than 1 EU/µg) (determined by LAL method).
10 µg/$266; 50 µg/$339; 500 µg/$1,010; 1 mg/$1,329
TNFRSF9 / 4-1BB / CD137 Protein
Select
E. coli
None
Biologically active
17.7 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
Select
CHO Cells
Human IgG1 Fc
Biologically active
Less than 0.06 EU/µg protein (determined by LAL method).
100 µg/$463
TNFRSF9 / 4-1BB / CD137 Protein - Active Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) by WB
Select
E. coli
His, N-Terminal
16kDa
10 µg/$283; 50 µg/$452; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
Select
HEK 293 Cells
Mouse IgG2a Fc, N-terminus
Biologically active
Less than 5.0 EU/mg protein (determined by LAL method).
~55 kDa (SDS-PAGE)
100 µg/$463
Select
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
18.1 kDa
10 µg/$266; 50 µg/$335
Select
Mammalian Cells
mFc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
43.8 kDa
10 µg/$281; 50 µg/$389
TNFRSF9 / 4-1BB / CD137 Protein
Select
HEK 293 Cells
DDK (Flag)-His, C-terminus
20 kDa
20 µg/$1,107
Select
E. coli
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
17.7 kDa
1 mg/$2,653; 20 µg/$364; 5 µg/$278
TNFRSF9 / 4-1BB / CD137 Protein - 12.5% SDS-PAGE of human TNFRSF9 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
54.3 kDa
10 µg/$479; 25 µg/$670
TNFRSF9 / 4-1BB / CD137 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
TNFRSF9 / 4-1BB / CD137 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
47 kDa
100 µg/$793; 1 mg/$3,499
TNFRSF9 / 4-1BB / CD137 Protein
Select
E. coli
His
100 µg/$411; 500 µg/$985; 20 µg/$276
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
17.7 kDa
5 µg/$268; 20 µg/$349
TNFRSF9 / 4-1BB / CD137 Protein
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~18 kDa
20 µg/$291; 100 µg/$490; 1 mg/$2,059
Select
E. coli
His
Less than 0.1 EU/µg protein (determined by LAL method).
25 µg/$421
Select
Human Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
44.7kD
10 µg/$277; 50 µg/$395; 500 µg/$1,203; 1 mg/$1,627
Select
Human Cells
Fc-6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
44kD
10 µg/$284; 50 µg/$365; 500 µg/$1,408; 1 mg/$2,059
TNFRSF9 / 4-1BB / CD137 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Mammalian Cells
Fc-6His, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
44 kDa
50 µg/$414; 10 µg/$308; 1 mg/$2,708; 500 µg/$1,701
TNFRSF9 / 4-1BB / CD137 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Mammalian Cells
6His, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
18.1 kDa
50 µg/$385; 10 µg/$269; 1 mg/$2,451; 500 µg/$1,612
TNFRSF9 / 4-1BB / CD137 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Mammalian Cells
Fc, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
44.2 kDa
50 µg/$385; 10 µg/$269; 1 mg/$2,451; 500 µg/$1,612
Select
HEK 293 Cells
Human IgG1 Fc
Less than 0.1 EU/µg protein (determined by LAL method).
~50kDa (SDS-PAGE)
50 µg/$414
Select
HEK 293 Cells
Human IgG1 Fc
Less than 0.01 EU/µg protein (determined by LAL method).
~50kDa (SDS-PAGE)
50 µg/$393
Select
CHO Cells
Human IgG1 Fc, C-terminus
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
55-60 kDa
1 mg/$1,475; 50 µg/$313
Viewing 1-25 of 33 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).