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TNFRSF6B / DCR3

tumor necrosis factor receptor superfamily, member 6b, decoy

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively. Unlike DcR1 and DcR2, DcR3 is a soluble rather than a membrane associated molecule. DcR3 binds to FasL and LIGHT and inhibits FasL and LIGHT induced apoptosis. DcR3 transcript is expressed in a number of lung and colon carcinomas and in some normal tissues.

Gene Name: tumor necrosis factor receptor superfamily, member 6b, decoy
Family/Subfamily: TNF Receptor , not assigned-TNF Receptor
Synonyms: TNFRSF6B, Decoy receptor 3, DJ583P15.1.1, DCR3, M68E, M68, TR6, Decoy receptor for Fas ligand
Target Sequences: NM_032945 NP_003814.1 O95407

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Products
Proteins (9)
Over-Expression Lysate (5)
Recombinant (4)
TNFRSF6B / DCR3 (9)
No (9)
Fc (1)
GST, N-terminus (1)
His (1)
Human IgG1 Fc (1)
Myc-DDK (Flag) (5)
Human (7)
293T Cells (3)
Baculovirus (1)
CHO Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (3)
Low endotoxin level (2)
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CHO Cells
Human IgG1 Fc
Less than 0.06 EU/µg protein (determined by LAL method).
100 µg/$480
TNFRSF6B / DCR3 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
TNFRSF6B / DCR3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
32.5 kDa
100 µg/$494
TNFRSF6B / DCR3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
32.5 kDa
100 µg/$494
TNFRSF6B / DCR3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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293T Cells
Myc-DDK (Flag)
32.5 kDa
20 µg/$150
TNFRSF6B / DCR3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
32.5 kDa
20 µg/$150
TNFRSF6B / DCR3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
32.5 kDa
20 µg/$150
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Baculovirus
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
56.4 kDa
100 µg/$1,047; 1 mg/$4,903
Viewing 1-9 of 9 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).