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TNFRSF17 / BCMA

tumor necrosis factor receptor superfamily, member 17

TNFRSF17 / BCMA is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.

Gene Name: tumor necrosis factor receptor superfamily, member 17
Family/Subfamily: TNF Receptor , not assigned-TNF Receptor
Synonyms: TNFRSF17, B cell maturation antigen, BCMA, CD269 antigen, B-cell maturation factor, B-cell maturation protein, BCM, CD269
Target Sequences: NM_001192 NP_001183.2 Q02223

☰ Filters
Products
Proteins (33)
Over-Expression Lysate (2)
Recombinant (31)
TNFRSF17 / BCMA (33)
Bind (1)
ELISA (1)
Func (1)
SDS-PAGE (6)
No (33)
6His, C-terminus (1)
6His-DDK (Flag), N-terminus (1)
Fc (2)
Fc, C-terminus (5)
Fc-AVI, C-terminus (1)
GST (1)
His (4)
His,C-terminus (2)
His-Fc (1)
Human IgG Fc, C-terminus (1)
Human IgG1 Fc (2)
Human IgG1 Fc, C-terminus (1)
Human IgG1 Fc, N-terminus (1)
mFc, C-terminus (1)
Mouse IgG2a Fc, C-terminus (1)
Myc-DDK (Flag) (2)
Rabbit IgG Fc, N-terminus (1)
Crab-eating macaque (1)
Cynomolgus (1)
Human (21)
Mouse (8)
Rat (1)
293T Cells (1)
E. coli (8)
HEK 293 Cells (10)
Human (4)
Human Cells (3)
Mammalian Cells (5)
Pichia pastoris (1)
Wheat Germ Extract (1)
Purified (9)
Low endotoxin level (26)
Biologically active (4)
TNFRSF17 / BCMA Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
TNFRSF17 / BCMA Protein - 12.5% SDS-PAGE of human TNFRSF17 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
45.98 kDa
10 µg/$479; 25 µg/$670
TNFRSF17 / BCMA Protein
Select
E. coli
None
Biologically active
5.4 kDa
5 µg/$282; 100 µg/$1,466; 500 µg/$3,025
TNFRSF17 / BCMA Protein - Recombinant Tumor Necrosis Factor Receptor Superfamily, Member 17 By SDS-PAGE
Select
E. coli
His
14.0 kDa
10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164
Select
E. coli
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
5.4 kDa
1 mg/$4,545; 20 µg/$364
TNFRSF17 / BCMA Protein
Select
HEK 293 Cells
His,C-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human TNFRSF17 consists of 65 amino acids and predicts a molecular mass of 7.3 kDa.
50 µg/$372; 500 µg/$1,285
Select
HEK 293 Cells
Human IgG1 Fc
Less than 0.01 EU/µg protein (determined by LAL method).
~35kDa (SDS-PAGE)
50 µg/$351
Select
E. coli
None
Less than 0.1 ng/µg of protein (less than 1EU/µg).
5.3 kDa
5 µg/$268; 20 µg/$349
TNFRSF17 / BCMA Protein - Measured by its binding ability in a functional ELISA. Immobilized TNFRSF17 can bind Fc-BAFF/Biotin, the EC50 of Fc-BAFF/Biotin is 1.0-10.0 ng/mL.
Select
HEK 293 Cells
Rabbit IgG Fc, N-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human TNFRSF17 consists 303 amino acids and predicts a molecular mass of 33.3 kDa.
1 mg/$2,344; 100 µg/$488
TNFRSF17 / BCMA Protein
Select
HEK 293 Cells
Human IgG1 Fc, N-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant mouse BCMA/Fc is a disulfide-linked homodimer The reduced monomer consists of 307 amino acids and has a predicted molecular mass of 33.8 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm BCMA/Fc monomer is approximately 40 kDa due to glycosylation.
100 µg/$441; 1 mg/$2,344
TNFRSF17 / BCMA Protein - Measured by its binding ability in a functional ELISA. Immobilized human BAFF at 10 µg/ml (100 µl/well) can bind mouse BCMA-Fch, The EC50 of mouse BCMA-Fch is 0.02-0.06 µg/mL.
Select
HEK 293 Cells
Human IgG1 Fc, C-terminus
Bind ELISA Func SDS-PAGE
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant mouse BCMA/Fc chimera is a disulfide-linked homodimer The reduced monomer consists of 297 amino acids and has a predicted molecular mass of 33.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm BCMA/Fc monomer is approximately 35-48 kDa due to glycosylation.
100 µg/$441
Select
Human
None
Less than 1.0 EU/µg protein (determined by LAL method).
32.1kD
50 µg/$395; 500 µg/$1,585; 1 mg/$2,157; 10 µg/$277
TNFRSF17 / BCMA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
20 kDa
20 µg/$150
TNFRSF17 / BCMA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
20 kDa
100 µg/$494
Select
Mammalian Cells
Fc, C-terminus
Less than 0.1 ng/mL (Less than 1 EU/µg) (determined by LAL method).
10 µg/$269; 50 µg/$372; 500 µg/$1,245; 1 mg/$1,627
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
32.8 kDa
10 µg/$269; 50 µg/$368
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
32.1 kDa
10 µg/$277; 50 µg/$389
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
33.1 kDa
10 µg/$288; 50 µg/$436
Select
Mammalian Cells
mFc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
32.5 kDa
10 µg/$297; 50 µg/$460
TNFRSF17 / BCMA Protein - Recombinant Human BCMA/TNFRSF17 (C-Fc-Avi) Biotinylated
Select
Human
Fc-AVI, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
34.6 kDa
20 µg/$416; 100 µg/$910
TNFRSF17 / BCMA Protein - Recombinant Cynomolgus BCMA/TNFRSF17 (C-6His)
Select
Human
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
7 kDa
10 µg/$290; 50 µg/$446
TNFRSF17 / BCMA Protein - Recombinant Human BCMA/TNFRSF17 (N-6His-Flag)
Select
Human
6His-DDK (Flag), N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
7.7 kDa
10 µg/$290; 50 µg/$446
Select
E. coli
106 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
11.77 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
Select
E. coli
114 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
12.65 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
Select
HEK 293 Cells
Mouse IgG2a Fc, C-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human TNFRSF17 consists of 287 amino acids and predicts a molecular mass of 32.3 kDa.
100 µg/$480
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).