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TNFAIP8 / SCC-S2

tumor necrosis factor, alpha-induced protein 8

Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.

Gene Name:	tumor necrosis factor, alpha-induced protein 8
Synonyms:	TNFAIP8, GG2-1, MDC-3.13, NDED, TNF alpha-induced protein 8, TNF-induced protein GG2-1, SCCS2, SCC-S2
Target Sequences:	NM_014350 NP_055165.2 O95379

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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