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TNFAIP2

tumor necrosis factor, alpha-induced protein 2

TNFAIP2 was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of this gene was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein, which suggested that this gene may be a retinoic acid target gene in acute promyelocytic leukemia.

Gene Name: tumor necrosis factor, alpha-induced protein 2
Synonyms: TNFAIP2, B94, EXOC3L3, TNF alpha-induced protein 2
Target Sequences: NM_006291 NP_006282.2 Q03169

Publications (1)

1
Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes. Hannah Scheiblich, Cira Dansokho, Dilek Mercan, Susanne V Schmidt, Luc Bousset, Lena Wischhof, Frederik Eikens, Alexandru Odainic, Jasper Spitzer, Angelika Griep, Stephanie Schwartz, Daniele Bano, Eicke Latz, Ronald Melki, Michael T Heneka. Cell. 2021 Sep;184:5089-5106.e21. [Full Text Article] [PubMed:34555357] [PMC:PMC8527836] Related Antibodies: LS-C386457.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).