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Unfortunately, the antibody (ID:147650) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



TNC / Tenascin C

tenascin C

Tenascin C (TNC) is the founding member of the gene family. In the embryo it is made by migrating cells like the neural crest; it is also abundant in developing tendons, bone and cartilage. The basic structure is 14 EGF-like repeats towards the N-terminal end, and 8 or more fibronectin-III domains which vary upon species and variant. TNC has anti-adhesive properties, causing cells in tissue culture to become rounded after it is added to the medium. One mechanism to explain this may come from its ability to bind to the extracellular matrix glycoprotein fibronectin and block fibronectin's interactions with specific syndecans. The expression of tenascin-C in the stroma of certain tumors is associated with a poor prognosis.

Gene Name: tenascin C
Family/Subfamily: Fibronectin , not assigned-Fibronectin
Synonyms: TNC, 150-225, Cytotactin, GP, Hexabrachion (tenascin), GMEM, GP 150-225, Miotendinous antigen, Myotendinous antigen, JI, Tenascin, Tenascin C, Neuronectin, Tenascin-C isoform 14/AD1/16, TN-C, Hexabrachion, HXB, Tenascin-C, TN
Target Sequences: NM_002160 NP_002151.2 P24821

Publications (13)

1
Involvement of large tenascin-C splice variants in breast cancer progression. Tsunoda T, Inada H, Kalembeyi I, Imanaka-Yoshida K, Sakakibara M, Okada R, Katsuta K, Sakakura T, Majima Y, Yoshida T. The American journal of pathology. 2003 162:1857-67. [PubMed:12759243] [PMC:PMC1868127]
2
Tenascin-C regulates recruitment of myofibroblasts during tissue repair after myocardial injury. Tamaoki M, Imanaka-Yoshida K, Yokoyama K, Nishioka T, Inada H, Hiroe M, Sakakura T, Yoshida T. The American journal of pathology. 2005 167:71-80. [PubMed:15972953] [PMC:PMC1603439]
3
Switch to an invasive growth phase in melanoma is associated with tenascin-C, fibronectin, and procollagen-I forming specific channel structures for invasion. Kriinen E, Nummela P, Soikkeli J, Yin M, Lukk M, Jahkola T, Virolainen S, Ora A, Ukkonen E, Saksela O, Hltt E. The Journal of pathology. 2006 210:181-91. [PubMed:16924594]
4
Expression of large tenascin-C splice variants by hepatic stellate cells/myofibroblasts in chronic hepatitis C. El-Karef A, Kaito M, Tanaka H, Ikeda K, Nishioka T, Fujita N, Inada H, Adachi Y, Kawada N, Nakajima Y, Imanaka-Yoshida K, Yoshida T. Journal of hepatology. 2007 46:664-73. [PubMed:17188391]
5
B and C domain containing tenascin-C: urinary markers for invasiveness of urothelial carcinoma of the urinary bladder?. Richter P, Tost M, Franz M, Altendorf-Hofmann A, Junker K, Borsi L, Neri D, Kosmehl H, Wunderlich H, Berndt A. Journal of cancer research and clinical oncology. 2009 135:1351-8. [PubMed:19326143]
6
Increased presence of stromal myofibroblasts and tenascin-C with malignant progression in canine mammary tumors. Yoshimura H, Michishita M, Ohkusu-Tsukada K, Takahashi K. Veterinary pathology. 2011 48:313-21. [PubMed:20571146]
7
Expression of tenascin-C and its isoforms in the breast. Guttery DS, Shaw JA, Lloyd K, Pringle JH, Walker RA. Cancer metastasis reviews. 2010 29:595-606. [PubMed:20814719]
8
A migration signature and plasma biomarker panel for pancreatic adenocarcinoma. Balasenthil S, Chen N, Lott ST, Chen J, Carter J, Grizzle WE, Frazier ML, Sen S, Killary AM. Cancer prevention research (Philadelphia, Pa.). 2011 4:137-49. [PubMed:21071578]
9
Regeneration of the perineurium after microsurgical resection examined with immunolabeling for tenascin-C and alpha smooth muscle actin. Yamamoto M, Okui N, Tatebe M, Shinohara T, Hirata H. Journal of anatomy. 2011 218:413-25. [PubMed:21265831] [PMC:PMC3077524]
10
Novel effects of CCN3 that may direct the differentiation of chondrocytes. Janune D, Kubota S, Nishida T, Kawaki H, Perbal B, Iida S, Takigawa M. FEBS letters. 2011 585:3033-40. [PubMed:21871891]
11
Promoting effects of carminic acid-enriched cochineal extracts on capsular invasive thyroid carcinomas through targeting activation of angiogenesis in rats. Kemmochi S, Shimamoto K, Shiraki A, Onda N, Hasumi K, Suzuki K, Mitsumori K, Shibutani M. The Journal of toxicological sciences. 2012 37:475-82. (IHC; Rat) [PubMed:22687987]
12
Lac color inhibits development of rat thyroid carcinomas through targeting activation of plasma hyaluronan-binding protein. Kemmochi S, Yamamichi S, Shimamoto K, Onda N, Hasumi K, Suzuki K, Mitsumori K, Shibutani M. Experimental biology and medicine (Maywood, N.J.). 2012 237:728-38. (IHC; Rat) [PubMed:22715430]
13
Direct progression of capsular invasive carcinomas from subcapsular focal hyperplasias induced by hypothyroidism-mediated tumor promotion in a rat two-stage thyroid carcinogenesis model. Ago K, Kemmochi S, Morita R, Yafune A, Shiraki A, Mitsumori K, Shibutani M. Journal of cancer research and clinical oncology. 2013 139:395-401. (IHC; Rat) [PubMed:23114882]
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Filtered By: None
Target
tnc-tenascin-c (121)
Reactivity
Human (104)
Mouse (18)
Rat (22)
Chicken (2)
Pig (2)
Rabbit (1)
Zaire Ebolavirus (4)
Application
IHC (42)
IHC-Fr (8)
IHC-P (31)
WB (99)
Flo (6)
ELISA (41)
ICC (30)
IF (8)
IP (11)
Host
rabbit (41)
mouse (76)
goat (2)
chicken (1)
rat (1)
Isotype
IgG (39)
IgG1 (27)
IgG1,k (44)
IgG2a (2)
IgY (1)
Clonality
monoclonal mc (77)
polyclonal pc (44)
Clone
3B4 (1)
4C8MS (5)
4F10TT (1)
DB7 (2)
EB2 (2)
SPM319 (3)
STn 219 (1)
T20 (4)
T2H5 (12)
Format
AP Conjugated (6)
APC Conjugated (5)
Azide-free (3)
Biotin Conjugated (17)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (16)
HRP Conjugated (9)
Magnetic beads Conjugated (1)
PE Conjugated (6)
Ready-to-Use (2)
Sepharose Conjugated (1)
Unconjugated (57)
Epitope
aa49-181 (6)
C-Terminus (3)
aa174-621 (3)
aa175-342 (3)
aa356-495 (3)
aa513-621 (3)
N-Terminus (2)
aa186-625 (2)
Internal (1)
aa 1888-2201 (1)
aa18-175 (1)
aa1869-1882 (1)
aa2021-2036 (1)
Publications
No (121)
Showing 1-25 out of 121 results
Anti-TNC / Tenascin C Antibody (C-Terminus) IHC-plus™ LS-B8789

Rabbit Polyclonal (IgG) to Human TNC / Tenascin C
Human
IHC-P
Unconjugated
Anti-TNC / Tenascin C Antibody (clone T2H5) LS-C11466

Mouse Monoclonal [clone T2H5] (IgG1) to Human TNC / Tenascin C
Human
ELISA IHC-Fr IHC-P IP WB
Unconjugated
Anti-TNC / Tenascin C Antibody (clone DB7) LS-C202511

Mouse Monoclonal [clone DB7] (IgG2a) to Human TNC / Tenascin C
Human
IF IHC-P WB
Unconjugated
Anti-TNC / Tenascin C Antibody (aa2021-2036) LS-C313183

Rabbit Polyclonal to Mouse TNC / Tenascin C
Mouse, Rat, Human
IHC-P WB
Unconjugated
Anti-TNC / Tenascin C Antibody LS-C39574

Rabbit Polyclonal (IgG) to Chicken TNC / Tenascin C
Chicken
IHC-Fr IHC-P WB
Unconjugated
Anti-TNC / Tenascin C Antibody (clone T2H5) IHC-plus™ LS-B5150

Mouse Monoclonal [clone T2H5] (IgG1) to Human TNC / Tenascin C
Human
IHC-P
Unconjugated
Anti-TNC / Tenascin C Antibody (clone 4F10TT) LS-C193612

Mouse Monoclonal [clone 4F10TT] (IgG1) to Human TNC / Tenascin C
Chicken, Rabbit, Mouse, Rat, Human
IHC WB
Unconjugated
Anti-TNC / Tenascin C Antibody LS-C414970

Rabbit Polyclonal to Human TNC / Tenascin C
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
Anti-TNC / Tenascin C Antibody (C-Terminus) LS-C387634

Rabbit Polyclonal (IgG) to Human TNC / Tenascin C
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
Anti-TNC / Tenascin C Antibody (clone 3B4) LS-C197477

Mouse Monoclonal [clone 3B4] (IgG1,k) to Human TNC / Tenascin C
Human
ELISA WB
Unconjugated
Anti-TNC / Tenascin C Antibody (C-Terminus) LS-C413317

Rabbit Polyclonal to Human TNC / Tenascin C
Mouse, Pig, Human
IHC-P WB
Unconjugated
Anti-TNC / Tenascin C Antibody (aa18-175) LS-C39587

Chicken Polyclonal (IgY) to Human TNC / Tenascin C
Human
ELISA WB
Unconjugated
Anti-TNC / Tenascin C Antibody (aa174-621) LS-C374294

Rabbit Polyclonal (IgG) to Mouse TNC / Tenascin C
Mouse
WB
Unconjugated
Anti-TNC / Tenascin C Antibody (Biotin) LS-C316622

Rabbit Polyclonal (IgG) to Human TNC / Tenascin C
Human
ELISA IHC-P
Biotin Conjugated
Anti-TNC / Tenascin C Antibody (Biotin) LS-C211511

Rabbit Polyclonal (IgG) to Human TNC / Tenascin C
Human
ELISA IHC-P
Biotin Conjugated
Anti-TNC / Tenascin C Antibody (clone T2H5) LS-C85454

Mouse Monoclonal [clone T2H5] (IgG1,k) to Human TNC / Tenascin C
Human
Unconjugated
Anti-TNC / Tenascin C Antibody LS-C39577

Mouse Monoclonal (IgG1,k) to Human TNC / Tenascin C
Human
ELISA ICC IHC WB
Unconjugated
Anti-TNC / Tenascin C Antibody (HRP) LS-C549785

Mouse Monoclonal (IgG1,k) to Human TNC / Tenascin C
Human
ELISA ICC IHC WB
HRP Conjugated
Anti-TNC / Tenascin C Antibody (Biotin) LS-C529697

Mouse Monoclonal (IgG1,k) to Human TNC / Tenascin C
Human
ELISA ICC IHC WB
Biotin Conjugated
Anti-TNC / Tenascin C Antibody (FITC) LS-C539614

Mouse Monoclonal (IgG1,k) to Human TNC / Tenascin C
Human
ELISA ICC IHC WB
FITC Conjugated
Anti-TNC / Tenascin C Antibody (APC) LS-C519486

Mouse Monoclonal (IgG1,k) to Human TNC / Tenascin C
Human
ELISA ICC IHC WB
APC Conjugated
Anti-TNC / Tenascin C Antibody (AP) LS-C511594

Mouse Monoclonal (IgG1,k) to Human TNC / Tenascin C
Human
ELISA ICC IHC WB
AP Conjugated
Anti-TNC / Tenascin C Antibody (PE) LS-C657758

Mouse Monoclonal (IgG1,k) to Human TNC / Tenascin C
Human
ELISA ICC IHC WB
PE Conjugated
Anti-TNC / Tenascin C Antibody (clone T20) LS-C415238

Mouse Monoclonal [clone T20] (IgG1) to Human TNC / Tenascin C
Human
ELISA ICC IHC WB
Unconjugated
Anti-TNC / Tenascin C Antibody (clone T20, Magnetic beads) LS-C171286

Mouse Monoclonal [clone T20] (IgG1) to Human TNC / Tenascin C
Human
IP
Magnetic beads Conjugated

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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