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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TMPRSS2 / Epitheliasin

transmembrane protease, serine 2

Serine protease that proteolytically cleaves and activates the viral spike glycoproteins which facilitate virus-cell membrane fusions; spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence. Facilitates human SARS coronavirus (SARS-CoV) infection via two independent mechanisms, proteolytic cleavage of ACE2, which might promote viral uptake, and cleavage of coronavirus spike glycoprotein which activates the glycoprotein for cathepsin L-independent host cell entry. Proteolytically cleaves and activates the spike glycoproteins of human coronavirus 229E (HCoV-229E) and human coronavirus EMC (HCoV-EMC) and the fusion glycoproteins F0 of Sendai virus (SeV), human metapneumovirus (HMPV), human parainfluenza 1, 2, 3, 4a and 4b viruses (HPIV). Essential for spread and pathogenesis of influenza A virus (strains H1N1, H3N2 and H7N9); involved in proteolytic cleavage and activation of hemagglutinin (HA) protein which is essential for viral infectivity.

Gene Name: transmembrane protease, serine 2
Family/Subfamily: Protease , Serine S1
Synonyms: TMPRSS2, Epitheliasin, PRSS10, Serine protease 10, PP9284
Target Sequences: NM_005656 NP_005647.3 O15393

Filtered By: None
Target
TMPRSS2 / Epitheliasin (42)
Reactivity
Human (32)
Mouse (18)
Rat (7)
Bovine (4)
Pig (4)
Rabbit (4)
Application
IHC (23)
IHC-P (8)
WB (39)
Flo (2)
ELISA (3)
ICC (3)
Peptide-ELISA (1)
Host
rabbit (40)
mouse (1)
goat (1)
Isotype
IgG (27)
IgG2a,k (1)
Clonality
monoclonal mc (2)
polyclonal pc (40)
Clone
2F4 (1)
EPR3862 (1)
Format
APC (2)
APC Conjugated (2)
Biotin Conjugated (6)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (6)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (18)
Epitope
aa254-490 (10)
aa284-492 (10)
C-Terminus (4)
N-Terminus (4)
Extracellular Domain (1)
aa1-30 (1)
aa100-470 (1)
aa314-343 (1)
aa518-529 (1)
Publications
No (42)
Showing 1-25 of 42 results

TMPRSS2 / Epitheliasin Antibody (Extracellular Domain, clone EPR3862) IHC-plus™ LS-B8961
Rabbit Monoclonal [clone EPR3862] to Human TMPRSS2 / Epitheliasin
Mouse, Rat, Human
ICC IHC IHC-P WB
Unconjugated
50µl  $425.00
Anti-TMPRSS2 / Epitheliasin antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Western blot analysis on human prostate tissue lysate using anti-TMPRSS2 antibody.
Anti-TMPRSS2 / Epitheliasin antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Western blot analysis on human prostate tissue lysate using anti-TMPRSS2 antibody.

TMPRSS2 / Epitheliasin Antibody (aa1-30) LS-C100563
Rabbit Polyclonal to Human TMPRSS2 / Epitheliasin
Human
Flo IHC IHC-P WB
Unconjugated
400µl  $305.00
TMPRSS2 Antibody (RB18784) IHC of formalin-fixed and paraffin-embedded human testis tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Western blot of TMPRSS2 Antibody in 293, NCI-H460 cell line lysates (35 ug/lane). TMPRSS2 (arrow) was detected using the purified antibody.
TMPRSS2 Antibody (RB18784) IHC of formalin-fixed and paraffin-embedded human testis tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Western blot of TMPRSS2 Antibody in 293, NCI-H460 cell line lysates (35 ug/lane). TMPRSS2 (arrow) was detected using the purified antibody.

TMPRSS2 / Epitheliasin Antibody (aa284-492) LS-C296775
Rabbit Polyclonal (IgG) to Human TMPRSS2 / Epitheliasin
Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $530.00; 10ml 0.5mg/ml  $2,100.00
Western blot of recombinant TMPRSS2 / Epitheliasin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant TMPRSS2 / Epitheliasin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TMPRSS2 / Epitheliasin Antibody (aa284-492, Biotin) LS-C300336
Rabbit Polyclonal (IgG) to Human TMPRSS2 / Epitheliasin
Human
WB
Biotin Conjugated
100µl 0.5mg/ml  $375.00
Western blot of recombinant TMPRSS2 / Epitheliasin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant TMPRSS2 / Epitheliasin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TMPRSS2 / Epitheliasin Antibody (aa284-492, Biotin) LS-C687465
Rabbit Polyclonal (IgG) to Human TMPRSS2 / Epitheliasin
Human
IHC WB
Biotin Conjugated
20µl  $205.00; 100µl  $265.00; 200µl  $315.00; 1ml  $575.00; 10ml  $2,310.00
Western blot of recombinant TMPRSS2 / Epitheliasin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant TMPRSS2 / Epitheliasin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TMPRSS2 / Epitheliasin Antibody (aa284-492, FITC) LS-C303304
Rabbit Polyclonal (IgG) to Human TMPRSS2 / Epitheliasin
Human
WB
FITC Conjugated
100µl 0.5mg/ml  $395.00
Western blot of recombinant TMPRSS2 / Epitheliasin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant TMPRSS2 / Epitheliasin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TMPRSS2 / Epitheliasin Antibody (aa284-492, FITC) LS-C694292
Rabbit Polyclonal (IgG) to Human TMPRSS2 / Epitheliasin
Human
IHC WB
FITC Conjugated
20µl  $215.00; 100µl  $275.00; 200µl  $325.00; 1ml  $635.00; 10ml  $2,520.00
Western blot of recombinant TMPRSS2 / Epitheliasin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant TMPRSS2 / Epitheliasin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TMPRSS2 / Epitheliasin Antibody (aa100-470) IHC-plus™ LS-B14093
Rabbit Polyclonal (IgG) to Human TMPRSS2 / Epitheliasin
Human
IHC IHC-P WB
Unconjugated
50µl 1mg/ml  $425.00
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

TMPRSS2 / Epitheliasin Antibody IHC-plus™ LS-B14581
Rabbit Polyclonal to Human TMPRSS2 / Epitheliasin
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
50µl 1mg/ml  $425.00
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot analysis of TMPRSS2 expression in 22RV1 (A) whole cell lysates.
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot analysis of TMPRSS2 expression in 22RV1 (A) whole cell lysates.

TMPRSS2 / Epitheliasin Antibody IHC-plus™ LS-B14876
Rabbit Polyclonal (IgG) to Human TMPRSS2 / Epitheliasin
Mouse, Human
IHC IHC-P WB
Unconjugated
50µl  $425.00
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunohistochemistry of paraffin-embedded human stomach cancer using TMPRSS2 antibody at dilution of 1:200 (400x lens).
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunohistochemistry of paraffin-embedded human stomach cancer using TMPRSS2 antibody at dilution of 1:200 (400x lens).

TMPRSS2 / Epitheliasin Antibody LS-C661116
Rabbit Polyclonal (IgG) to Human TMPRSS2 / Epitheliasin
Human
ELISA IHC WB
Unconjugated
100µg  $435.00

TMPRSS2 / Epitheliasin Antibody (aa254-490) LS-C373022
Rabbit Polyclonal (IgG) to Mouse TMPRSS2 / Epitheliasin
Mouse
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $265.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $545.00; 10ml 0.5mg/ml  $2,160.00
Western blot of TMPRSS2 / Epitheliasin antibody.
Western blot of TMPRSS2 / Epitheliasin antibody.

TMPRSS2 / Epitheliasin Antibody (aa254-490, HRP) LS-C711931
Rabbit Polyclonal (IgG) to Mouse TMPRSS2 / Epitheliasin
Mouse
IHC WB
HRP Conjugated
20µl  $215.00; 100µl  $295.00; 200µl  $345.00; 1ml  $695.00; 10ml  $2,805.00
Western blot of TMPRSS2 / Epitheliasin antibody.
Western blot of TMPRSS2 / Epitheliasin antibody.

TMPRSS2 / Epitheliasin Antibody (aa254-490, Biotin) LS-C687464
Rabbit Polyclonal (IgG) to Mouse TMPRSS2 / Epitheliasin
Mouse
IHC WB
Biotin Conjugated
20µl  $205.00; 100µl  $275.00; 200µl  $315.00; 1ml  $590.00; 10ml  $2,370.00
Western blot of TMPRSS2 / Epitheliasin antibody.
Western blot of TMPRSS2 / Epitheliasin antibody.

TMPRSS2 / Epitheliasin Antibody (aa254-490, Biotin) LS-C422638
Rabbit Polyclonal (IgG) to Mouse TMPRSS2 / Epitheliasin
Mouse
ICC WB
Biotin Conjugated
100µl 0.5mg/ml  $375.00

TMPRSS2 / Epitheliasin Antibody (aa254-490, FITC) LS-C694290
Rabbit Polyclonal (IgG) to Mouse TMPRSS2 / Epitheliasin
Mouse
IHC WB
FITC Conjugated
20µl  $215.00; 100µl  $285.00; 200µl  $335.00; 1ml  $650.00; 10ml  $2,580.00
Western blot of TMPRSS2 / Epitheliasin antibody.
Western blot of TMPRSS2 / Epitheliasin antibody.

TMPRSS2 / Epitheliasin Antibody (aa254-490, FITC) LS-C422639
Rabbit Polyclonal (IgG) to Mouse TMPRSS2 / Epitheliasin
Mouse
ICC WB
FITC Conjugated
100µl 0.5mg/ml  $395.00

TMPRSS2 / Epitheliasin Antibody (aa254-490, Cy3) LS-C702901
Rabbit Polyclonal (IgG) to Mouse TMPRSS2 / Epitheliasin
Mouse
IHC WB
Cy3 Conjugated
20µl  $245.00; 100µl  $365.00; 200µl  $445.00; 1ml  $1,080.00; 10ml  $4,320.00
Western blot of TMPRSS2 / Epitheliasin antibody.
Western blot of TMPRSS2 / Epitheliasin antibody.

TMPRSS2 / Epitheliasin Antibody (aa254-490, APC) LS-C718040
Rabbit Polyclonal (IgG) to Mouse TMPRSS2 / Epitheliasin
Mouse
IHC WB
APC Conjugated
20µl  $225.00; 100µl  $315.00; 200µl  $375.00; 1ml  $815.00; 10ml  $5,100.00
Western blot of TMPRSS2 / Epitheliasin antibody.
Western blot of TMPRSS2 / Epitheliasin antibody.

TMPRSS2 / Epitheliasin Antibody (aa254-490, PE) LS-C725988
Rabbit Polyclonal (IgG) to Mouse TMPRSS2 / Epitheliasin
Mouse
IHC WB
PE Conjugated
20µl  $215.00; 100µl  $285.00; 200µl  $335.00; 1ml  $650.00; 10ml  $2,580.00
Western blot of TMPRSS2 / Epitheliasin antibody.
Western blot of TMPRSS2 / Epitheliasin antibody.

TMPRSS2 / Epitheliasin Antibody (aa254-490, APC, Cy7) LS-C734936
Rabbit Polyclonal (IgG) to Mouse TMPRSS2 / Epitheliasin
Mouse
IHC WB
APC, Cy7 Conjugated
20µl  $285.00; 100µl  $465.00; 200µl  $650.00; 1ml  $1,620.00; 10ml  $6,480.00
Western blot of TMPRSS2 / Epitheliasin antibody.
Western blot of TMPRSS2 / Epitheliasin antibody.

TMPRSS2 / Epitheliasin Antibody LS-C342249
Rabbit Polyclonal to Human TMPRSS2 / Epitheliasin
Mouse, Rat, Human
IHC WB
Unconjugated
100µl 1mg/ml  $385.00

TMPRSS2 / Epitheliasin Antibody (clone 2F4) LS-C198350
Mouse Monoclonal [clone 2F4] (IgG2a,k) to Human TMPRSS2 / Epitheliasin
Human
ELISA WB
Unconjugated
100µg  $355.00
Detection limit for recombinant GST tagged TMPRSS2 is approximately 3 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged TMPRSS2 is approximately 3 ng/ml as a capture antibody.

TMPRSS2 / Epitheliasin Antibody (aa314-343) LS-C100564
Rabbit Polyclonal to Human TMPRSS2 / Epitheliasin
Human
Flo WB
Unconjugated
400µl  $305.00
Western blot of TMPRSS2 antibody in HepG2 cell line lysates (35 ug/lane). TMPRSS2 (arrow) was detected using the purified antibody.
TMPRSS2 Antibody flow cytometry of HepG2 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Western blot of TMPRSS2 antibody in HepG2 cell line lysates (35 ug/lane). TMPRSS2 (arrow) was detected using the purified antibody.
TMPRSS2 Antibody flow cytometry of HepG2 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

TMPRSS2 / Epitheliasin Antibody LS-C405257
Rabbit Polyclonal (IgG) to Human TMPRSS2 / Epitheliasin
Human
ELISA WB
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Western blot analysis of A549 cell, using TMPRSS2 Polyclonal Antibody at dilution of 1:350.
Western blot analysis of A549 cell, using TMPRSS2 Polyclonal Antibody at dilution of 1:350.
Showing 1-25 of 42 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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