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TMEM127 is a transmembrane protein with 3 predicted transmembrane domains. The protein is associated with a subpopulation of vesicular organelles corresponding to early endosomal structures, with the Golgi, and with lysosomes, and may participate in protein trafficking between these structures. Mutations in this gene and several other genes cause pheochromocytomas. Alternatively spliced transcript variants encoding the same protein have been identified.
Gene Name: | transmembrane protein 127 |
Synonyms: | TMEM127, Transmembrane protein 127 |
Target Sequences: | NM_017849 NP_060319.1 |
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