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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TMC6

transmembrane channel-like 6

Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs.

Gene Name: transmembrane channel-like 6
Synonyms: TMC6, EV1, EVIN1, Protein LAK-4, LAK-4P, Transmembrane channel-like 6, EVER1
Target Sequences: NM_007267 NP_009198.4 Q7Z403

Filtered By: None
Target
TMC6 (10)
Reactivity
Human (10)
Mouse (2)
Rat (1)
Application
IHC (2)
IHC-P (1)
WB (10)
ELISA (9)
IF (1)
Host
rabbit (10)
Isotype
IgG (9)
Clonality
polyclonal pc (10)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (4)
Epitope
aa160-188 (8)
Internal (1)
N-Terminus (1)
Publications
No (10)
Showing 1-10 of 10 results

TMC6 Antibody (N-Terminus) IHC-plus™ LS-B2699
Rabbit Polyclonal (IgG) to Human TMC6
Mouse, Rat, Human
ELISA IHC IHC-P WB
Unconjugated
50µg 1mg/ml  $425.00
Anti-TMC6 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Western blot of EVER1 in A-20 cell lysate with EVER1 antibody at (A) 1 and (B) 2 ug/ml.
Anti-TMC6 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Western blot of EVER1 in A-20 cell lysate with EVER1 antibody at (A) 1 and (B) 2 ug/ml.

TMC6 Antibody (Internal) LS-C53286
Rabbit Polyclonal (IgG) to Human TMC6
Mouse, Human
ELISA IF IHC WB
Unconjugated
50µg 1mg/ml  $365.00
Immunohistochemistry of EVER1 in human spleen with EVER1 antibody at 2.5 µg/mL.
Immunofluorescence of EVER1 in Human Spleen cells with EVER1 antibody at 20 ug/ml.
Immunohistochemistry of EVER1 in human spleen with EVER1 antibody at 2.5 µg/mL.
Immunofluorescence of EVER1 in Human Spleen cells with EVER1 antibody at 20 ug/ml.

TMC6 Antibody (aa160-188) LS-C325774
Rabbit Polyclonal (IgG) to Human TMC6
Human
ELISA WB
Unconjugated
200µl  $530.00

TMC6 Antibody (aa160-188, Biotin) LS-C271641
Rabbit Polyclonal (IgG) to Human TMC6
Human
ELISA WB
Biotin Conjugated
200µl  $680.00

TMC6 Antibody (aa160-188, FITC) LS-C271640
Rabbit Polyclonal (IgG) to Human TMC6
Human
ELISA WB
FITC Conjugated
200µl  $680.00

TMC6 Antibody (aa160-188, APC) LS-C271639
Rabbit Polyclonal (IgG) to Human TMC6
Human
ELISA WB
APC Conjugated
200µl  $680.00

TMC6 Antibody (aa160-188, Azide-free, HRP) LS-C271642
Rabbit Polyclonal (IgG) to Human TMC6
Human
ELISA WB
HRP Conjugated, Azide-free
200µl  $680.00

TMC6 Antibody (aa160-188, PE) LS-C271643
Rabbit Polyclonal (IgG) to Human TMC6
Human
ELISA WB
PE Conjugated
200µl  $680.00

TMC6 Antibody (aa160-188, AP) LS-C271638
Rabbit Polyclonal (IgG) to Human TMC6
Human
ELISA WB
AP Conjugated
200µl  $680.00

TMC6 Antibody (aa160-188) LS-C161946
Rabbit Polyclonal to Human TMC6
Human
WB
Unconjugated
400µl  $305.00
TMC6 Antibody western blot of A2058 cell line lysates (35 ug/lane). The TMC6 antibody detected the TMC6 protein (arrow).
TMC6 Antibody western blot of A2058 cell line lysates (35 ug/lane). The TMC6 antibody detected the TMC6 protein (arrow).
Showing 1-10 of 10 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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