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RNX (HOX11L2, TLX3) belongs to a family of orphan homeobox genes that encode DNA-binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine-47 replacing cytosine in the highly conserved homeodomain (Dear et al., 1993 [PubMed 8099440]).[supplied by OMIM, Mar 2008]
Gene Name: | T-cell leukemia homeobox 3 |
Synonyms: | TLX3, Homeobox protein Hox-11L2, HOX11L2, Homeo box 11-like 2, RNX, T-cell leukemia homeobox 3, T-cell leukemia, homeobox 3 |
Target Sequences: | NM_021025 NP_066305.2 O43711 |
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