Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
TLX1 / HOX11 is a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T-cell acute lymphoblastic leukemias. Alternate splicing results in multiple transcript variants.
Gene Name: | T-cell leukemia homeobox 1 |
Synonyms: | TLX1, Homeobox protein Hox-11, HOX11, T-cell leukemia homeobox 1, Proto-oncogene TCL-3, TCL3, T-cell leukemia, homeobox 1 |
Target Sequences: | NM_005521 NP_005512.1 P31314 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.