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TLR7 / CD287

toll-like receptor 7

TLR7 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.

Gene Name: toll-like receptor 7
Family/Subfamily: Toll-like Receptor , not assigned-Toll-like Receptor
Synonyms: TLR7, Toll-like receptor 7, CD287
Target Sequences: NM_016562 NP_057646.1 Q9NYK1

Publications (1)

1
Hepatitis C Virus Sensing by Human Trophoblasts Induces Innate Immune Responses and Recruitment of Maternal NK Cells: Potential Implications for Limiting Vertical Transmission. Giugliano S, Petroff MG, Warren BD, Jasti S, Linscheid C, Ward A, Kramer A, Dobrinskikh E, Sheiko MA, Gale M Jr, Golden-Mason L, Winn VD, Rosen HR. Journal of immunology (Baltimore, Md. : 1950). 2015 195:3737-47. (WB, IHC-P; Human) [Full Text Article] [PubMed:26342030] [PMC:PMC4592818]

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Proteins (6)
Recombinant (6)
TLR7 / CD287 (6)
No (6)
10His, N-terminus + Myc, C-terminus (2)
6His, N-terminus (1)
GST (1)
GST, N-terminus (1)
His-T7 (1)
Human (3)
Mouse (3)
E. coli (5)
Wheat Germ Extract (1)
Purified (3)
TLR7 / CD287 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His, N-terminus + Myc, C-terminus
43.8 kDa
1 mg/$1,679; 100 µg/$500; 20 µg/$364
TLR7 / CD287 Protein - Recombinant Toll Like Receptor 7 By SDS-PAGE
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E. coli
6His, N-terminus
21.4 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
TLR7 / CD287 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
10His, N-terminus + Myc, C-terminus
29.5 kDa
20 µg/$364; 1 mg/$1,679; 100 µg/$500
TLR7 / CD287 Protein
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E. coli
GST
64.2 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
TLR7 / CD287 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
TLR7 / CD287 Protein - Recombinant Toll Like Receptor 7 By SDS-PAGE
Select
E. coli
His-T7
21.3 kDa
10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).