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TLR7 / CD287

toll-like receptor 7

TLR7 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.

Gene Name: toll-like receptor 7
Family/Subfamily: Toll-like Receptor , not assigned-Toll-like Receptor
Synonyms: TLR7, Toll-like receptor 7, CD287
Target Sequences: NM_016562 NP_057646.1 Q9NYK1

Publications (1)

1
Hepatitis C Virus Sensing by Human Trophoblasts Induces Innate Immune Responses and Recruitment of Maternal NK Cells: Potential Implications for Limiting Vertical Transmission. Giugliano S, Petroff MG, Warren BD, Jasti S, Linscheid C, Ward A, Kramer A, Dobrinskikh E, Sheiko MA, Gale M Jr, Golden-Mason L, Winn VD, Rosen HR. Journal of immunology (Baltimore, Md. : 1950). 2015 195:3737-47. (WB, IHC-P; Human) [Full Text Article] [PubMed:26342030] [PMC:PMC4592818]

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Products
Antibodies (71)
Primary (71)
TLR7 / CD287 (71)
Human (59)
Mouse (31)
Rat (4)
Monkey (1)
IHC (26)
IHC-Fr (5)
IHC-P (10)
WB (53)
Flo (14)
ELISA (24)
ICC (5)
IF (4)
Peptide-ELISA (1)
rabbit (59)
mouse (12)
Product Group
IHCPlus (4)
IgG (36)
IgG1 (2)
IgG1,k (7)
IgG2a (2)
monoclonal mc (12)
polyclonal pc (59)
4F4 (1)
4G6 (1)
ABM2C27 (2)
IMG4G6 (2)
APC (2)
APC Conjugated (5)
Azide-free (6)
Biotin Conjugated (7)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (10)
HRP Conjugated (7)
PE Conjugated (7)
PerCP Conjugated (1)
Unconjugated (30)
aa887-1036 (8)
aa890-1037 (8)
aa899-926 (7)
aa98-128 (7)
C-Terminus (6)
aa562-839 (3)
aa706-728 (3)
aa 500-900 (2)
aa360-516 (2)
Internal (1)
aa1020-1038 (1)
aa1020-1047 (1)
aa451-500 (1)
aa465-483 (1)
aa650-700 (1)
aa900-950 (1)
No (71)
TLR7 / CD287 Antibody - Anti-TLR7 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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TLR7 / CD287 Rabbit anti-Human Polyclonal (aa900-950) Antibody
Human, Monkey
Flo, IHC, IHC-P, WB
Unconjugated
50 µg/$460
TLR7 / CD287 Antibody - Anti-TLR7 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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TLR7 / CD287 Rabbit anti-Human Polyclonal (aa706-728) Antibody
Mouse, Human
Flo, IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µg/$460
TLR7 / CD287 Antibody - Anti-TLR7 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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TLR7 / CD287 Rabbit anti-Human Polyclonal (aa465-483) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$460
TLR7 / CD287 Antibody - Intracellular flow cytometry of TLR7 in 10^6 human BDCM cells using 1 ul of Monoclonal Antibody to TLR7 (Clone IMG4G6)PE Conjugate (red) and 0.5 ug of mouse IgG1 isotype control (green, This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TLR7 / CD287 Mouse anti-Human Monoclonal (aa562-839) (PE) (IMG4G6) Antibody
Human
Flo
PE Conjugated
100 µl/$416
TLR7 / CD287 Antibody
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TLR7 / CD287 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$575
TLR7 / CD287 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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TLR7 / CD287 Rabbit anti-Human Polyclonal (aa98-128) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
TLR7 / CD287 Antibody - The Ramos cell lysates (80 µg) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human TLR7 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Arrow indicates TLR7 protein in human Ramos cells.
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TLR7 / CD287 Mouse anti-Human Monoclonal (aa451-500) (4F4) Antibody
Human
ELISA, WB
Unconjugated
50 µl/$303; 100 µl/$365
TLR7 / CD287 Antibody - Immunohistochemistry of formalin-fixed paraffin-embedded (FFPE) human thyroid cancer using TLR7 antibody at dilution of 1:100 (40x magnification).
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TLR7 / CD287 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
TLR7 / CD287 Antibody - Intracellular flow analysis of TLR7 in Balb/c mouse splenocytes using Polyclonal Antibody to TLR7 (Toll-like receptor 7) FITC Conjugate at 1 ug/10^6 cells. Green represents rabbit IgG isotype control; red represents anti-TLR7 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TLR7 / CD287 Rabbit anti-Human Polyclonal (aa706-728) (FITC) Antibody
Mouse, Human
Flo
FITC Conjugated
100 µl/$416
TLR7 / CD287 Antibody - IHC of human colon tissue using Polyclonal Antibody to TLR7 (Toll-like receptor 7) Azide-free (top) and an isotype control (bottom) at 5 ug/ml. This image was taken for the unmodified form of this product. Other forms have not been tested.
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TLR7 / CD287 Rabbit anti-Human Polyclonal (aa706-728) (Azide-free) Antibody
Mouse, Human
Flo, IHC, IHC-Fr, IHC-P, WB
Unconjugated, Azide-free
100 µg/$386
TLR7 / CD287 Antibody - Intracellular flow analysis of TLR7 in 1x10^6 Ramos cells using 0.5 ug of antibody. Shaded histogram represents Ramos cells without antibody; green represents isotype control;red represents anti-TLR7.
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TLR7 / CD287 Rabbit anti-Human Polyclonal (aa650-700) Antibody
Mouse, Human
Flo, IHC, IHC-Fr
Unconjugated
0.1 mg/$386
TLR7 / CD287 Antibody - 1:100 staining human brain carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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TLR7 / CD287 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
TLR7 / CD287 Antibody - Western blot of human TLR7 antibody in Ramos and transfected 293T lysate using TLR7 monoclonal antibody at 10 ug/ml.
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TLR7 / CD287 Mouse anti-Human Monoclonal (aa562-839) (IMG4G6) Antibody
Human
Flo, WB
Unconjugated
100 µg/$386
TLR7 / CD287 Antibody - Western Blot Positive WB detected in: Jurkat whole cell lysate, K562 whole cell lysate, A549 whole cell lysate All lanes: Tlr7 antibody at 2µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 122 kDa Observed band size: 122 kDa
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TLR7 / CD287 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
TLR7 / CD287 Antibody - Western Blot: TLR7 Antibody (4G6) [Azide Free] - TLR7 antibodies tested at 2 ug/ml on recombinant partial hTLR7 protein (amino acids 562-839). This image was taken for the unmodified form of this product. Other forms have not been tested.
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TLR7 / CD287 Mouse anti-Human Monoclonal (aa562-839) (Azide-free) (4G6) Antibody
Human
Flo, ICC, IF, WB
Unconjugated, Azide-free
0.1 mg/$386
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TLR7 / CD287 Mouse anti-Human Monoclonal (aa360-516) (PerCP) Antibody
Human
Flo
PerCP Conjugated
100 Tests/$930
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TLR7 / CD287 Mouse anti-Human Monoclonal (aa360-516) (PE) Antibody
Human
Flo
PE Conjugated
100 Tests/$930
TLR7 / CD287 Antibody - TLR7 antibody IHC-paraffin. IHC(P): Mouse Thymus Tissue.
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TLR7 / CD287 Rabbit anti-Human Polyclonal (aa1020-1047) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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TLR7 / CD287 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
TLR7 / CD287 Antibody - Fig-1: Immunohistochemical analysis of TLR7 in human Kidney tissue using TLR7 antibody at 5 µg/ml.
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TLR7 / CD287 Mouse anti-Human Monoclonal (Azide-free) Antibody
Human
Flo, IHC
Unconjugated, Azide-free
100 µg/$414
TLR7 / CD287 Antibody - Anti-TLR7 antibody, IHC(P): Human Placenta Tissue
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TLR7 / CD287 Rabbit anti-Human Polyclonal (aa1020-1038) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
TLR7 / CD287 Antibody
Select
TLR7 / CD287 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321
Select
TLR7 / CD287 Rabbit anti-Human Polyclonal (aa98-128) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
TLR7 / CD287 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
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TLR7 / CD287 Mouse anti-Human Monoclonal (aa 500-900) (ABM2C27) Antibody
Human
Flo, IHC-P, WB
Unconjugated
100 µg/$477
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).